WITHDRAWN: Modified sham feeding in women with bulimia nervosa and healthy controls

Appetite ◽  
2006 ◽  
Author(s):  
B.T. Walsh ◽  
D.A. Klein ◽  
G.P. Smith ◽  
J.S. Schebendach ◽  
M.J. Devlin
2000 ◽  
Vol 15 (5) ◽  
pp. 302-305 ◽  
Author(s):  
J. Rabe-Jablonska Jolanta ◽  
M. Sobow Tomasz

SummaryThe aim of the study was to search for a body dysmorphic disorder (BDD) period preceding the symptoms meeting the criteria of either anorexia or bulimia nervosa, and an evaluation of the prevalence of BDD symptoms in a control group of girls without any eating disorder. Ninety-three girls (12–21 years old) were included in the study (36 with anorexia nervosa, 17 with bulimia nervosa and 40 healthy controls). The Structured Clinical Interview (SCID), including the BDD module, and a novel questionnaire (for the presence of preceding life events) were used. We found the symptoms of BDD in 25% of anorexia nervosa sufferers for at least six months before observing a clear eating disorder picture. Moreover, other mental disorders were also present among these patients. The results may support the idea that BDD and anorexia nervosa both belong to either OCD or affective disorders spectra.


2016 ◽  
Vol 33 (S1) ◽  
pp. S161-S162
Author(s):  
M. Nigro ◽  
A.M. Monteleone ◽  
L. Steardo ◽  
G. Patriciello ◽  
V. Di Maso ◽  
...  

IntroductionSome temperament characteristics of personality seem to be modulated by oxytocin. Patients suffering from eating disorders (EDs) display aberrant personality traits.Objectives and aimsWe investigated the relationships between plasma oxytocin levels and personality dimensions of patients with anorexia nervosa (AN) and bulimia nervosa (BN) and compared them to those of healthy controls.MethodsPlasma oxytocin levels were measured in 23 women with AN, 27 women with BN and 19 healthy controls and assessed their personality traits by means of the Cloninger's Temperament and Character Inventory-Revised (TCI-R).ResultsAN patients showed plasma levels of the hormone significantly lower than BN and healthy controls. In healthy women, plasma oxytocin levels resulted significantly correlated negatively with novelty seeking scores and positively with both harm avoidance (HA) scores and the attachment subscale scores of the reward dependence: these correlations explained 82% of the variability in circulating oxytocin. In BN patients, plasma oxytocin resulted negatively correlated with HA, whereas no significant correlations emerged in AN patients.ConclusionsThese findings confirm a dysregulation of oxytocin secretion in AN but not in BN and show, for the first time, that the association of circulating oxytocin to patients’ temperament traits is totally lost in underweight patients with AN and partially lost or even inverted in women with BN. These findings suggest a role of oxytocin in certain deranged behaviours of ED patients, which are influenced by the subjects’ personality traits.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2011 ◽  
Vol 26 (S2) ◽  
pp. 741-741
Author(s):  
U. Volpe ◽  
S. Galderisi ◽  
A. Mucci ◽  
A. Vignapiano ◽  
V. Montefusco ◽  
...  

Body image distortion represents a key clinical feature of eating disorders (EDs), but its neurobiological underpinnings are poorly understood. Previous functional imaging studies yielded inconsistent findings, indicating a possible involvement of fronto-temporal and/or limbic abnormalities. Since these putative regions are highly interconnected and participate into functional networks, it might be useful to study the temporal evolution of their activation during the processing of body images.The present study was aimed to explore the neurobiological correlates of body image processing in subjects with bulimia nervosa (BN), using the high-time resolution, electrical neuroimaging technique called LORETA.Event-related potentials (ERPs) were recorded from 30 unipolar channels in 10 subjects with BN and 10 matched healthy controls, during the performance of an emotional counting Stroop task, in which the distorted, non-distorted and scrambled image of their own body and an unfamiliar body image were randomly presented on a computer screen.Using the LORETA source imaging technique, we found that subjects with BN had a greater activation in frontal areas and anterior cingulate during late phases of body image processing, with respect to healthy controls.Our results indicate that patients with BN need to allocate a greater amount of attentive and executive resources, than healthy controls, during the integrative stage of body shape processing.


2009 ◽  
Vol 96 (1) ◽  
pp. 44-50 ◽  
Author(s):  
D.A. Klein ◽  
J.E. Schebendach ◽  
A.J. Brown ◽  
G.P. Smith ◽  
B.T. Walsh
Keyword(s):  

2004 ◽  
Vol 10 (4) ◽  
pp. 513-520 ◽  
Author(s):  
KATE TCHANTURIA ◽  
MARIJA BRECELJ ANDERLUH ◽  
ROBIN G. MORRIS ◽  
SOPHIA RABE-HESKETH ◽  
DAVID A. COLLIER ◽  
...  

The aim of this study was to determine if there are differences in cognitive flexibility in anorexia nervosa and bulimia nervosa. Fifty-three patients with an eating disorder (34 with anorexia nervosa and 19 with bulimia nervosa) and 35 healthy controls participated in the study. A battery of neuropsychological tests for cognitive flexibility was used, including Trail Making B, the Brixton Test, Verbal Fluency, the Haptic Illusion Test, a cognitive shifting task (CatBat) and a picture set test. Using exploratory factor analysis, four factors were obtained: 1: Simple Alternation; 2: Mental Flexibility; 3: Perseveration; and 4: Perceptual Shift. Patients with anorexia nervosa had abnormal scores on Factors 1 and 4. Patients with bulimia nervosa showed a different pattern, with significant impairments in Factors 2 and 4. These findings suggest that differential neuropsychological disturbance in the domain of mental flexibility/rigidity may underlie the spectrum of eating disorders. (JINS, 2004, 10, 513–520.)


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