Uncontrolled eating in healthy women has limited influence on food cue reactivity and food-related inhibitory control

Appetite ◽  
2021 ◽  
pp. 105767
Author(s):  
Maud Grol ◽  
Luis Cásedas ◽  
Danna Oomen ◽  
Desiree B. Spronk ◽  
Elaine Fox
Keyword(s):  
Inhibitory Control ◽  
Cue Reactivity ◽  
Healthy Women ◽  
Uncontrolled Eating

scholarly journals Uncontrolled Eating in Healthy Women Has Limited Influence on Food Reward Sensitivity and Food-Related Inhibitory Control

2020 ◽  
Author(s):  
Maud Grol ◽  
Luis Cásedas ◽  
Danna Oomen ◽  
Desirée Spronk ◽  
Elaine Fox
Keyword(s):  
Individual Differences ◽  
Food Consumption ◽  
Inhibitory Control ◽  
Response Inhibition ◽  
Food Reward ◽  
Reward Sensitivity ◽  
Specific Response ◽  
High Tendency ◽  
Healthy Women ◽  
Uncontrolled Eating

Uncontrolled eating—in the general population—is characterized by overeating, hedonic hunger and being drawn towards palatable foods. Theoretically, it is the result of a strong food reward signal in relation to a poor ability to exert inhibitory control. How food consumption influences inhibitory control and food reward sensitivity, and how this relates to the continued urge to eat, remains unclear though. We used fMRI (N=40) in order to investigate the neural mechanism underlying food reward sensitivity and food-specific response inhibition (go-nogo task), by comparing women reporting high versus low/average uncontrolled eating across two sessions: during an inter-meal hunger state and after consumption of a high-caloric snack. We found no effects of individual differences in uncontrolled eating, food consumption, nor their interaction on food reward sensitivity. Differences in uncontrolled eating and food consumption did interact in modulating activity in the left superior occipital gyrus during response inhibition of non-food stimuli, an area previously associated with successful nogo- vs. go-trials. Yet, behavioural performance on the go-nogo task was not modulated by uncontrolled eating nor food consumption. Women with a low/average tendency for uncontrolled eating may need more cognitive resources to support successful response inhibition of non-food stimuli during food ‘go’ blocks in an inter-meal hunger state, whereas women with a high tendency for uncontrolled eating showed this after food consumption. Considering current and previous findings, it seems that individual differences in uncontrolled eating in healthy women have only limited influence on food reward sensitivity and food-related inhibitory control, whereas differences in weight status (e.g., obesity) may have more impact.

scholarly journals Beating uncontrolled eating: Training inhibitory control to reduce food intake and food cue sensitivity

Appetite ◽  
2018 ◽  
Vol 131 ◽  
pp. 73-83 ◽  
Author(s):  
Danna Oomen ◽  
Maud Grol ◽  
Desiree Spronk ◽  
Charlotte Booth ◽  
Elaine Fox
Keyword(s):  
Food Intake ◽  
Inhibitory Control ◽  
Reduce Food Intake ◽  
Uncontrolled Eating

Neuroimaging the Effects of Drug-Related Cue-Reactivity on Inhibitory Control in Cocaine Use Disorder

2020 ◽  
Vol 87 (9) ◽  
pp. S314-S315
Author(s):  
Ahmet O. Ceceli ◽  
Muhammad Parvaz ◽  
Matthew Schafer ◽  
Pias Malaker ◽  
Nelly Alia-Klein ◽  
...  
Keyword(s):  
Inhibitory Control ◽  
Cue Reactivity ◽  
Cocaine Use

scholarly journals Altered prefrontal signaling during inhibitory control in a salient drug context in human cocaine addiction

2021 ◽  
Author(s):  
Ahmet O. Ceceli ◽  
Muhammad A. Parvaz ◽  
Sarah King ◽  
Matthew Schafer ◽  
Pias Malaker ◽  
...  
Keyword(s):  
Drug Addiction ◽  
Inhibitory Control ◽  
Dorsolateral Prefrontal Cortex ◽  
Cue Reactivity ◽  
Self Control ◽  
Food Cues ◽  
Drug Cues ◽  
Dorsolateral Prefrontal ◽  
Valence And Arousal ◽  
Drug Cue

AbstractDrug addiction is characterized by impaired Response Inhibition and Salience Attribution (iRISA), where the salience of drug cues is postulated to overpower that of other reinforcers with a concomitant decrease in self-control. However, the neural underpinnings of the interaction between the salience of drug cues and inhibitory control in drug addiction remain unclear. We developed a novel stop-signal fMRI task where the stop-signal reaction time (SSRT—a classical inhibitory control measure) was tested under different salience conditions (modulated by drug, food, threat or neutral words) in individuals with cocaine use disorder (CUD; n=26) vs. demographically matched healthy control participants (HC; n=26). Despite similarities in drug cue-related SSRT and valence and arousal word ratings between groups, the dorsolateral prefrontal cortex (dlPFC) activity was diminished during the successful inhibition of drug versus food cues in CUD, and was correlated with lower frequency of recent use, lower craving, and longer abstinence (Z > 3.1, p < .05 corrected). Results suggest reduced involvement of cognitive control regions (e.g., dlPFC) during inhibitory control under a drug context, relative to an alternative reinforcer, in CUD. Supporting the iRISA model, these results elucidate the direct impact of drug-related cue-reactivity on the neural signature of inhibitory control in drug addiction.Significance statementExcessive salience attribution to drugs and related cues at the expense of nondrug reinforcers and cues and inhibitory control impairments are hallmark symptoms of drug addiction. Although these neuropsychological functions have been investigated independently, brain representations of their interaction are less clear. We illustrate that, despite matched behavioral performance and valence and arousal ratings, the dorsolateral prefrontal cortex—a key node of the cognitive control network also associated with craving—exhibits decreased signaling when successfully inhibiting responses to drug compared to nondrug (food) cues (words) in cocaine-addicted individuals. Modulating salience while taxing self-control permits the study of their combined impact, an ecologically valid examination of the addiction experience. Better understanding inhibitory control under drug cue-reactivity may refine targeted neuromodulatory interventions.

Neurobiology of cue-reactivity, craving, and inhibitory control in non-substance addictive behaviors

2020 ◽  
Vol 415 ◽  
pp. 116952 ◽  
Author(s):  
Stephanie Antons ◽  
Matthias Brand ◽  
Marc N. Potenza
Keyword(s):  
Inhibitory Control ◽  
Cue Reactivity ◽  
Addictive Behaviors

scholarly journals Environmental Tobacco Smoke Exposure and Brain Functioning Associated with Smoking Cue-Reactivity and Inhibitory Control in Nonsmoking Adolescents

2021 ◽  
pp. 1-10
Author(s):  
Anna Johanna Maria Gemma Boormans ◽  
Joyce Dieleman ◽  
Marloes Kleinjan ◽  
Roy Otten ◽  
Maartje Luijten
Keyword(s):  
Nicotine Dependence ◽  
Inhibitory Control ◽  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Cue Reactivity ◽  
Brain Functioning ◽  
Smoking Cues ◽  
Wide Range ◽  
Smoking Cue Reactivity

<b><i>Introduction:</i></b> Despite its well-established negative effects, environmental tobacco smoke (ETS) exposure remains highly prevalent worldwide. ETS exposure is associated with a wide range of physical and mental health-related problems among youth, including an increased likelihood to develop nicotine dependence. Up till now, neurocognitive effects of ETS exposure are largely unknown, while such effects could explain the role of ETS exposure in the development of nicotine dependence. Therefore, this preregistered study investigated the role of current ETS exposure in brain functioning associated with smoking cue-reactivity and inhibitory control. <b><i>Method:</i></b> Concurrent with functional magnetic resonance imaging, nonsmoking adolescents aged 14–18 years (<i>N</i> = 51) performed a smoking cue-reactivity task, assessing brain functioning to smoking cues, and a Go/NoGo task measuring inhibitory control. ETS exposure was measured using a self-report questionnaire and biochemically verified. <b><i>Results:</i></b> No significant associations were observed between current ETS exposure and brain functioning associated with smoking cue-reactivity and inhibitory control. <b><i>Conclusion:</i></b> These findings suggest that low-to-moderate levels of current ETS exposure are not associated with increased salience of smoking cues or deficits in inhibitory control in nonsmoking adolescents. Longitudinal research is needed to further clarify the exact effect of lifetime ETS exposure on brain functioning, as well as research focusing on the effects of higher levels of ETS exposure.

scholarly journals Event-Related Potential Correlates of Biased Cognitive Processing and Control in Substance Abusers: A Review

2019 ◽  
Author(s):  
Hassan Khajehpour ◽  
Fahimeh Mohagheghian ◽  
Sepideh Bakht ◽  
Nasser Samadzadehaghdam ◽  
Ehsan Eqlimi ◽  
...  
Keyword(s):  
Inhibitory Control ◽  
Cognitive Processing ◽  
Substance Abusers ◽  
Cue Reactivity ◽  
Event Related Potentials ◽  
Event Related Potential ◽  
Error Processing ◽  
Related Potentials ◽  
Addiction Studies ◽  
And Control

Event-Related Potentials (ERPs) have been used in addiction studies to evaluate cognitive performance and craving in individuals with Substance Use Dependence (SUD). This paper reviews studies that used ERPs to investigate cue reactivity, inhibitory control and error processing in SUDs. Five abused substances are included in the investigation, i.e. alcohol, nicotine, cannabis, cocaine, and methamphetamine. For each substance, the main recent findings related to the ERPs are specifically discussed, according to the latency of ERPs. The results show that individuals with SUDs allocate more attention resources to the cognitive processing of substance-related cues, indexed by increased amplitude of middle and late latency ERPs. Laboratory observations also show amplitude enlargement for early latency ERPs. SUDs reveal a deficiency in the inhibitory control and conscious error processing, indexed by attenuated N2 and Pe amplitude. The cognitive and motor inhibitory component (P3) changes show a controversial result. This study expands the findings of previous related reviews implying that substance abusers allocate more attentional resources to drug cues indexed by enlarged P3 and LPP amplitude. Regarding P3 elicited in inhibitory control tasks, there is not still convergent results, while N2 and Pe become attenuated as reported in previous reviews. The outcomes also show that the chance of relapse to substance abuse could be predicted by recording ERPs reflecting inhibitory control and error processing.  

scholarly journals Emotional eating

Psico ◽  
2021 ◽  
Vol 52 (1) ◽  
pp. e35452
Author(s):  
Roberto Decker ◽  
Marcelle Matiazo Pinhatti ◽  
Thiago Gomes DeCastro ◽  
Lisiane Bizarro
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Inhibitory Control ◽  
Psychological Factors ◽  
Emotional Eating ◽  
Weight Status ◽  
Depression Symptoms ◽  
Biological Factors ◽  
Eating Style ◽  
Uncontrolled Eating

Emotional Eating (EE) is defined as eating under the influence of negative emotions, and is associated with Eating Disorders, impulsivity, depression and weight gain. However, previous literature is not clear regarding how these variables explain EE. The present study aimed to identify predictors of EE and its relationship to impulsivity, depression, eating style, and weight status in young adults. Sex differences in eating style were examined, and differences in EE between obese/overweight and normal/underweight individuals were tested. Two-hundred college students completed online questionnaires assessing all variables. Low inhibitory control, depression symptoms, female sex, and higher body mass index significantly predicted scores on EE. Obese/overweight and female participants presented increased EE. Correlation analysis evidenced positive associations between EE, Uncontrolled Eating, body mass, and low inhibitory control. Results indicate that EE is related to psychological factors such as impulsivity and depression, and to biological factors, such as sex and body mass.

Rebound acid hypersecretion after ranitidine is not due to impaired inhibitory control

2001 ◽  
Vol 120 (5) ◽  
pp. A158-A158 ◽  
Author(s):  
D GILLEN ◽  
A WIRZ ◽  
K MCCOLL
Keyword(s):  
Inhibitory Control ◽  
Acid Hypersecretion
Sign in / Sign up

Export Citation Format

Share Document