A new aquatic pathogen inhibitor produced by the marine fungus Aspergillus sp. LS116

Aquaculture ◽  
2020 ◽  
Vol 520 ◽  
pp. 734670
Author(s):  
Peng Xu ◽  
Lijian Ding ◽  
Jiaxin Wei ◽  
Qiang Li ◽  
Minjie Gui ◽  
...  
RSC Advances ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 4243-4250
Author(s):  
Yi Qiu ◽  
Qi Guo ◽  
Yan-Qin Ran ◽  
Wen-Jian Lan ◽  
Chi-Keung Lam ◽  
...  

Cytotoxic alkaloids from marine fungus Aspergillus sp. XBB-4 induced by an amino acid-directed strategy.


2011 ◽  
Vol 47 (4) ◽  
pp. 571-573 ◽  
Author(s):  
Mei-Yan Wei ◽  
Guang-Ying Chen ◽  
Yu Wang ◽  
Xiu-Li Zhang ◽  
Chang-Yun Wang ◽  
...  

2017 ◽  
Vol 32 (7) ◽  
pp. 815-820 ◽  
Author(s):  
Jinzhong Xu ◽  
Qian Hu ◽  
Wanjing Ding ◽  
Pinmei Wang ◽  
Yanan Di
Keyword(s):  

2015 ◽  
Vol 10 (8) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Pinmei Wang ◽  
Shizhe Zhao ◽  
Ying Liu ◽  
Wanjing Ding ◽  
Feng Qiu ◽  
...  

Asperginine (1), an alkaloid possessing a rare skeleton, was isolated from the cultural broth of the marine fungus Aspergillus sp. (Z-4) isolated from the gut of the marine isopod Ligia oceanica. The planar structure and relative configuration of 1 was determined by analysis of NMR and mass spectral data. Its absolute configuration was elucidated by Marfey's method, together with NOESY correlations of key hydrogen atoms. The cytotoxicity against prostate cancer PC3 and human HCT116 was assayed by the MTT method. Unfortunately, asperginine did not show any activity.


2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Zhong-Ji Qian ◽  
Chen Zhang ◽  
Yong-Xin Li ◽  
Jae-Young Je ◽  
Se-Kwon Kim ◽  
...  

Alcohol-induced liver injury progresses from fatty infiltration followed by a harmful cause of inflammation leading to an irreversible damage. In this study, two compounds (emodin and chrysophanol) isolated from marine fungusAspergillus sp.were examined for their protective effects against ethanol-induced toxicityin vitro. Ethanol-induced HepG2/CYP2E1 cells were treated with the compounds at various concentrations, and the results showed that there was a dose-dependent decrease of gamma-glutamyl transpeptidase (GGT) activity and increase of glutathione (GSH) in the culture media with an increase in cell viability. Furthermore, the protective effects of the compounds were evaluated by protein expression levels of GGT, GSH, and CYP2E1 using Western blot. Among the compounds, emodin addressed to the ethanol-induced cytotoxicity more effectively compared to the chrysophanol. It could be suggested that emodin isolated from this genus would be a potential candidate for attenuating ethanol induced liver damage for further industrial applications such as functional food and pharmaceutical developments.


Fitoterapia ◽  
2021 ◽  
pp. 104908
Author(s):  
Suoyu Cen ◽  
Jia Jia ◽  
Yichao Ge ◽  
Yihan Ma ◽  
Xinyang Li ◽  
...  
Keyword(s):  

2019 ◽  
Vol 60 (26) ◽  
pp. 1724-1726 ◽  
Author(s):  
Fuqian Wang ◽  
Zhenquan Hu ◽  
Chunshun Li ◽  
Xiaohua Wu ◽  
Shugeng Cao
Keyword(s):  

2008 ◽  
Vol 65 (1) ◽  
pp. 60-65 ◽  
Author(s):  
Zu-Jian Wu ◽  
Ming-An Ouyang ◽  
Qing-Wei Tan
Keyword(s):  

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