Sex differences in the association between the APOEε4 allele and hearing impairment: A longitudinal memory clinic study

2021 ◽  
Vol 95 ◽  
pp. 104418
Author(s):  
Chi-Hun Kim ◽  
Kang Ju Son ◽  
Jun Hong Lee ◽  
Jong Hun Kim
Keyword(s):  
Sex Differences ◽  
Hearing Impairment ◽  
Memory Clinic ◽  
Clinic Study

scholarly journals COGNITIVE AND HEARING IMPAIRMENTS IN OLDER ADULTS: EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S77-S77
Author(s):  
Jessica S West ◽  
Scott Lynch
Keyword(s):  
Older Adults ◽  
Sex Differences ◽  
Cognitive Impairment ◽  
Cognitive Decline ◽  
Hearing Impairment ◽  
Cognitive Impairments ◽  
Hearing Impairments ◽  
The Relationship ◽  
Retirement Study ◽  
Over Time

Abstract As the number of older adults increases, increased prevalence of cognitive and sensory impairments pose growing public health challenges. Research on the relationship between hearing impairment and cognition, however, is minimal and has yielded mixed results, with some studies finding that hearing impairment is associated with cognitive decline, and others reporting that the association is weak or non-existent. Most of this research has been conducted outside of the U.S., and the few U.S.-based longitudinal studies have relied mostly on small, non-representative samples involving short follow-up periods. Further, despite known gendered patterns in cognitive and hearing impairments, no studies to date have examined whether the relationship between the two varies by gender. Our study addresses these weaknesses in the literature by utilizing nine waves of the Health and Retirement Study (1998-2014; n=14,169), a large, nationally representative, longitudinal study that facilitates examination of long-term interrelationships between hearing and cognitive impairments. In this study, we use autoregressive latent trajectory (ALT) methods to model: 1) the relationship between hearing impairment and cognitive decline, and 2) sex differences in the relationship. ALT models enable us to determine whether hearing impairment and cognitive impairment are associated, net of their common tendency simply to co-trend with age. Results indicate that hearing and cognitive impairments are strongly interrelated processes that trend together over time. Moreover, hearing impairment has an increasing impact on cognitive impairment across age while the effect of cognitive impairment on hearing impairment levels out over time. Sex differences in these patterns are discussed.

P2-394: Impact of Disclosing Amyloid Status on Caregivers: A Memory Clinic Study

2016 ◽  
Vol 12 ◽  
pp. P796-P796
Author(s):  
Robert Laforce ◽  
Mohamed Reda Bensaidane ◽  
Jean-Mathieu Beauregard ◽  
Stephane Poulin ◽  
David Bergeron ◽  
...  
Keyword(s):  
Memory Clinic ◽  
Clinic Study

The Value of PET in Mild Cognitive Impairment, Typical and Atypical/Unclear Dementias: A Retrospective Memory Clinic Study

2010 ◽  
Vol 25 (4) ◽  
pp. 324-332 ◽  
Author(s):  
Robert Laforce ◽  
James P. Buteau ◽  
Nancy Paquet ◽  
Louis Verret ◽  
Michèle Houde ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Retrospective Memory ◽  
Memory Clinic ◽  
Clinic Study

Clinical utility of computed tomography in the assessment of dementia: a memory clinic study

2004 ◽  
Vol 19 (5) ◽  
pp. 414-421 ◽  
Author(s):  
Kelly A. Condefer ◽  
Judith Haworth ◽  
Gordon K. Wilcock
Keyword(s):  
Computed Tomography ◽  
Clinical Utility ◽  
Memory Clinic ◽  
Clinic Study

Effects of Monaural Asymmetry and Target–Masker Similarity on Binaural Advantage in Children and Adults With Normal Hearing

2020 ◽  
Vol 63 (8) ◽  
pp. 2811-2824
Author(s):  
Ji-Sheng Liu ◽  
Ya-Feng Yu ◽  
Duo-Duo Tao ◽  
Yi Li ◽  
Fei Ye ◽  
...  
Keyword(s):  
Sex Differences ◽  
Speech Recognition ◽  
Language Development ◽  
Hearing Impairment ◽  
Normal Hearing ◽  
Chinese Adults ◽  
Adults And Children ◽  
Binaural Listening ◽  
Competing Speech

Purpose For colocated targets and maskers, binaural listening typically offers a small but significant advantage over monaural listening. This study investigated how monaural asymmetry and target–masker similarity may limit binaural advantage in adults and children. Method Ten Mandarin-speaking Chinese adults (aged 22–27 years) and 12 children (aged 7–14 years) with normal hearing participated in the study. Monaural and binaural speech recognition thresholds (SRTs) were adaptively measured for colocated competing speech. The target–masker sex was the same or different. Performance was measured using headphones for three listening conditions: left ear, right ear, and both ears. Binaural advantage was calculated relative to the poorer or better ear. Results Mean SRTs were significantly lower for adults than children. When the target–masker sex was the same, SRTs were significantly lower with the better ear than with the poorer ear or both ears ( p < .05). When the target–masker sex was different, SRTs were significantly lower with the better ear or both ears than with the poorer ear ( p < .05). Children and adults similarly benefitted from target–masker sex differences. Substantial monaural asymmetry was observed, but the effects of asymmetry on binaural advantage were similar between adults and children. Monaural asymmetry was significantly correlated with binaural advantage relative to the poorer ear ( p = .004), but not to the better ear ( p = .056). Conclusions Binaural listening may offer little advantage (or even a disadvantage) over monaural listening with the better ear, especially when competing talkers have similar vocal characteristics. Monaural asymmetry appears to limit binaural advantage in listeners with normal hearing, similar to observations in listeners with hearing impairment. While language development may limit perception of competing speech, it does not appear to limit the effects of monaural asymmetry or target–masker sex on binaural advantage.

scholarly journals Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study

Brain ◽  
2016 ◽  
Vol 139 (9) ◽  
pp. 2540-2553 ◽  
Author(s):  
Antoine Leuzy ◽  
Konstantinos Chiotis ◽  
Steen G. Hasselbalch ◽  
Juha O. Rinne ◽  
Alexandre de Mendonça ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Amyloid Β ◽  
Memory Clinic ◽  
Pittsburgh Compound B ◽  
Clinic Study

scholarly journals P.064 Sex differences in patients referred to a rural and remote memory clinic

2017 ◽  
Vol 44 (S2) ◽  
pp. S29-S29
Author(s):  
OM Philippon ◽  
A Kirk ◽  
C Karunanayake ◽  
D Morgan
Keyword(s):  
Sex Differences ◽  
Daily Living ◽  
Demographic Data ◽  
Initial Presentation ◽  
Remote Memory ◽  
Memory Clinic ◽  
Rural And Remote ◽  
Assessment Scores ◽  
Mini Mental Status Examination ◽  
To Receive

Background: Dementia is more prevalent in women. Sex differences exist as the disease progresses (e.g. males are more likely to become aggressive). In many medical illnesses (e.g. cardiac disease), there are differences in presentation between men and women. The current study explores sex differences at the patients’ initial presentation to the Rural and Remote Memory Clinic (RRMC). Methods: Patients were referred to the RRMC in Saskatoon, Saskatchewan. Cognitive and demographic data were collected. Questionnaires included cognitive (e.g. Mini-Mental Status Examination) and daily living (e.g. Instrumental Activities of Daily Living) assessments. Results: Three hundred and seventy-five (159 male, 216 female) patients participated. Of these patients, 146 (49 male, 97 female) were diagnosed with Alzheimer’s disease. Males and females presented to the clinic at similar ages. Females were more likely to have a son or daughter caregiver and to live alone. Males were more likely to be currently working and to be a former smoker. No statistically significant differences were found for cognitive assessment scores. Conclusions: Analysis of the initial presentation of patients to the RRMC revealed females and males had similar presentation in measures of cognitive impairment. This may be reassuring for patients and their families knowing their family member, regardless of sex, is receiving equivalent referral to receive care.

Sign in / Sign up

Export Citation Format

Share Document