Development and Internal Validation of Supervised Machine Learning Algorithms for Predicting Clinically Significant Functional Improvement in a Mixed Population of Primary Hip Arthroscopy

Author(s):  
Kyle N. Kunze ◽  
Evan M. Polce ◽  
Benedict U. Nwachukwu ◽  
Jorge Chahla ◽  
Shane J. Nho
2020 ◽  
Vol 105 (10) ◽  
pp. e3706-e3717 ◽  
Author(s):  
Jacopo Burrello ◽  
Alessio Burrello ◽  
Jacopo Pieroni ◽  
Elisa Sconfienza ◽  
Vittorio Forestiero ◽  
...  

Abstract Context Primary aldosteronism (PA) comprises unilateral (lateralized [LPA]) and bilateral disease (BPA). The identification of LPA is important to recommend potentially curative adrenalectomy. Adrenal venous sampling (AVS) is considered the gold standard for PA subtyping, but the procedure is available in few referral centers. Objective To develop prediction models for subtype diagnosis of PA using patient clinical and biochemical characteristics. Design, Patients and Setting Patients referred to a tertiary hypertension unit. Diagnostic algorithms were built and tested in a training (N = 150) and in an internal validation cohort (N = 65), respectively. The models were validated in an external independent cohort (N = 118). Main outcome measure Regression analyses and supervised machine learning algorithms were used to develop and validate 2 diagnostic models and a 20-point score to classify patients with PA according to subtype diagnosis. Results Six parameters were associated with a diagnosis of LPA (aldosterone at screening and after confirmatory testing, lowest potassium value, presence/absence of nodules, nodule diameter, and computed tomography results) and were included in the diagnostic models. Machine learning algorithms displayed high accuracy at training and internal validation (79.1%-93%), whereas a 20-point score reached an area under the curve of 0.896, and a sensitivity/specificity of 91.7/79.3%. An integrated flowchart correctly addressed 96.3% of patients to surgery and would have avoided AVS in 43.7% of patients. The external validation on an independent cohort confirmed a similar diagnostic performance. Conclusions Diagnostic modelling techniques can be used for subtype diagnosis and guide surgical decision in patients with PA in centers where AVS is unavailable.


2021 ◽  
Vol 1916 (1) ◽  
pp. 012042
Author(s):  
Ranjani Dhanapal ◽  
A AjanRaj ◽  
S Balavinayagapragathish ◽  
J Balaji

2021 ◽  
Vol 11 (15) ◽  
pp. 6728
Author(s):  
Muhammad Asfand Hafeez ◽  
Muhammad Rashid ◽  
Hassan Tariq ◽  
Zain Ul Abideen ◽  
Saud S. Alotaibi ◽  
...  

Classification and regression are the major applications of machine learning algorithms which are widely used to solve problems in numerous domains of engineering and computer science. Different classifiers based on the optimization of the decision tree have been proposed, however, it is still evolving over time. This paper presents a novel and robust classifier based on a decision tree and tabu search algorithms, respectively. In the aim of improving performance, our proposed algorithm constructs multiple decision trees while employing a tabu search algorithm to consistently monitor the leaf and decision nodes in the corresponding decision trees. Additionally, the used tabu search algorithm is responsible to balance the entropy of the corresponding decision trees. For training the model, we used the clinical data of COVID-19 patients to predict whether a patient is suffering. The experimental results were obtained using our proposed classifier based on the built-in sci-kit learn library in Python. The extensive analysis for the performance comparison was presented using Big O and statistical analysis for conventional supervised machine learning algorithms. Moreover, the performance comparison to optimized state-of-the-art classifiers is also presented. The achieved accuracy of 98%, the required execution time of 55.6 ms and the area under receiver operating characteristic (AUROC) for proposed method of 0.95 reveals that the proposed classifier algorithm is convenient for large datasets.


Author(s):  
Charalambos Kyriakou ◽  
Symeon E. Christodoulou ◽  
Loukas Dimitriou

The paper presents a data-driven framework and related field studies on the use of supervised machine learning and smartphone technology for the spatial condition-assessment mapping of roadway pavement surface anomalies. The study explores the use of data, collected by sensors from a smartphone and a vehicle’s onboard diagnostic device while the vehicle is in movement, for the detection of roadway anomalies. The research proposes a low-cost and automated method to obtain up-to-date information on roadway pavement surface anomalies with the use of smartphone technology, artificial neural networks, robust regression analysis, and supervised machine learning algorithms for multiclass problems. The technology for the suggested system is readily available and accurate and can be utilized in pavement monitoring systems and geographical information system applications. Further, the proposed methodology has been field-tested, exhibiting accuracy levels higher than 90%, and it is currently expanded to include larger datasets and a bigger number of common roadway pavement surface defect types. The proposed system is of practical importance since it provides continuous information on roadway pavement surface conditions, which can be valuable for pavement engineers and public safety.


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