Laboratory cultures of field-collected larval tobacco budworm, Heliothis virescens (F.), beet army worm, Spodoptera exigua (Hübner), and fall armyworm, S. frugiperda (J. E. Smith) were bioassayed for response to three pyrethroids in combination with piperonyl butoxide (PBO), or MGK-264. The greatest synergistic effects were seen in S. exigua which also displayed the greatest tolerance to pyrethroids without synergists. The highest SR50 (synergist ratio) value for S. exigua was 22.1 with fenvalerate-PBO mixed in a ratio of 1:5, the highest for S. frugiperda was 4.6 with fenvalerate-MGK-264 1:5, and the highest for H. virescens was 1.3 with permethrin-MGK-264 1:5 or with fenvalerate-PBO 1:5.