Clinical Effectiveness of Leukocyte Filtration During Cardiopulmonary Bypass in Patients with Chronic Obstructive Pulmonary Disease

2004 ◽  
Vol 78 (4) ◽  
pp. 1339-1344 ◽  
Author(s):  
Theodoros E. Karaiskos ◽  
George M. Palatianos ◽  
Constantine D. Triantafillou ◽  
George H. Kantidakis ◽  
George M. Astras ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Cardiopulmonary Bypass ◽  
Pulmonary Disease ◽  
Clinical Effectiveness ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Leukocyte Filtration

scholarly journals The Effect of Different Regimens of Vaccination against Pneumococcal Infection on the Clinical Course of Chronic Obstructive Pulmonary Disease: Focus on Changes in Sputum Microorganism Population

2021 ◽  
Vol 99 (7) ◽  
pp. 7-17
Author(s):  
M. P. Kostinov ◽  
А. D. Protasov ◽  
А. V. Zhetkov ◽  
M. L. Shteyner ◽  
Yu. V. Tezikov ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Pneumococcal Infection ◽  
Pneumococcal Vaccination ◽  
Statistical Processing ◽  
Clinical Effectiveness ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Microorganism Population ◽  
History Of

The objective: development of the best vaccination regimen against pneumococcal infection in patients with chronic obstructive pulmonary disease (COPD) with consideration of changes in microbiological and clinical parameters.Subjects and Methods. 115 patients with COPD were randomized into 4 pneumococcal vaccination groups, they were examined and followed up for 4 years; 112 patients completed the study complying with the protocol. Detail medical history of all subjects was collected. To verify the diagnosis of COPD, all subjects underwent external respiratory function test and bronchodilator test (salbutamol, 400 μg) according to the standard method. The classic microbiological assessment was used in this study. The clinical effectiveness of vaccination was assessed. Statistical processing of the results was performed using StatPlus Pro 6.2.0.0 software (license number 2883).Results. Сonsecutive vaccination with pneumococcal conjugate and polysaccharide vaccines leads to decreased isolation rate of pneuniococcus from the sputum of CODP patients. The frequency of exacerbations, the need for antibiotic chemotherapy and hospitalizations also goes down.

scholarly journals Clinical effectiveness of reamberin in treating outpatients with chronic obstructive pulmonary disease

2014 ◽  
Vol 95 (6) ◽  
pp. 795-800
Author(s):  
O Yu Lakotsenina ◽  
L N Voit ◽  
E A Sokolova ◽  
M A Grankina
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Sodium Succinate ◽  
Pulmonary Ventilation ◽  
Clinical Effectiveness ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Breathing Exercises

Aim. To investigate the clinical effectiveness of meglumine sodium succinate in treating patients with chronic obstructive pulmonary disease in an outpatient setting. Methods. 93 patients with chronic obstructive pulmonary disease were examined. The influence of 3-month combined treatment with long-acting M-anticholinergic drug (tiotropium bromide), combination of salmeterol and fluticasone (Seretide) and antihypoxant drug - meglumine sodium succinate (Reamberin) in combination with breathing exercises on functional parameters of respiratory, cardiovascular system and quality of life was studied. Results. Signs of deceased pulmonary ventilation due to obstruction were revealed. Pulmonary hypertension and decreased right ventricle diastolic function were diagnosed in 89% of patients. Patients taking meglumine sodium succinate (Reamberin) showed statistically significant improvement of functional indices of respiratory and cardiovascular systems, as well as better quality of life after the treatment. In patients who were not taking meglumine sodium succinate, those changes were less prominent. Conclusion. Adding meglumine sodium succinate (Reamberin) to complex treatment of patients with chronic obstructive pulmonary disease supports the improvement in pulmonary function and macrocirculation, which demonstrates the improvement of pulmonary gas exchange function and improves quality of life.

Sign in / Sign up

Export Citation Format

Share Document