scholarly journals Differential association of flow velocities in the carotid artery with plaques, intima media thickness and cardiac function

Author(s):  
David Leander Rimmele ◽  
Katrin Borof ◽  
Jan-Per Wenzel ◽  
Märit Jensen ◽  
Christian-A. Behrendt ◽  
...  
2011 ◽  
Vol 27 (5) ◽  
pp. 214-219
Author(s):  
Omodele A. Olowoyeye ◽  
Smith I. Jaja ◽  
Michael O. Kehinde ◽  
Gbolahan O. Awosanya ◽  
Nicholas K. Irurhe ◽  
...  

2015 ◽  
Author(s):  
Dilek Tuzun ◽  
Ayten Oguz ◽  
Murat Sahin ◽  
Safa Ersen Ganidagli ◽  
Didem Atay ◽  
...  

2018 ◽  
Vol 69 (6) ◽  
pp. 1550-1553
Author(s):  
Rosana Manea ◽  
Bianca Elena Popovici ◽  
Carmen Daniela Neculoiu ◽  
Dan Minea ◽  
Alina Calin

Hypertension is a major risk factor for progression of the atherosclerotic process and for developing of degenerative cardiovascular diseases in adulthood. The aim of this study is to evaluate how the measurement of carotid intima - media thickness for prediction of essential hypertension in children can be used.The study group included 81 children and the control group 61 children, all aged between 5 - 17 years and 11 months old, and admitted in Children Hospital Brasov in the period of 2009 � 2014. The study protocol included: BMI, blood pressure and Doppler echography of the common carotid artery for each group. Mean age of the patients from the study group was 13.67 years, 43.20 % girls and 56.80 % boys, while in the control group, the mean age was 14.07 years, 54.10% girls and 45.90 % boys. 70.37% of the children from the study group presented obesity, while in the control group 40.98% were obese. The IMTC study group ranged from 0.52 - 0.69 mm and the limits of the normotensive subjects were 0.32 -0.54 mm. In both groups the obese patients were found to have increased carotid artery intima-media, which means that IMTC was positively correlated with BMI (p=0.000001).It is necessary to identify diagnostic methods easily applicable for children, allowing involvement of the characteristics of the arterial wall in the degenerative pathological processes. Increased intima-media ratio is positively correlated with high values of blood pressure.


2008 ◽  
Vol 63 (3) ◽  
pp. 309-313 ◽  
Author(s):  
H. Heuten ◽  
I. Goovaerts ◽  
G. Ennekens ◽  
C. Vrints

2005 ◽  
Vol 30 (5) ◽  
pp. 464-468 ◽  
Author(s):  
J.A. Reid ◽  
C. Wolsley ◽  
L.L. Lau ◽  
R.J. Hannon ◽  
B. Lee ◽  
...  

Andrologia ◽  
2021 ◽  
Author(s):  
Khaled Fawzy El Mulla ◽  
Amr El Abd ◽  
Hanaa Mahmoud Donia ◽  
Reham Magdy Hussein ◽  
Amira Abulfotooh Eid

2009 ◽  
Vol 31 (10) ◽  
pp. 713-716 ◽  
Author(s):  
Aydın Erdemir ◽  
Neşat Çullu ◽  
Uluç Yiş ◽  
Fatih Demircioğlu ◽  
Mustafa Kır ◽  
...  

2021 ◽  
Vol 12 ◽  
pp. 204062232110269
Author(s):  
Yipin Zhao ◽  
Huawei Wang ◽  
Dazhi Ke ◽  
Wei Deng ◽  
Yingying Ji ◽  
...  

Background and Aims: Studies have shown that dipeptidyl peptidase-4 (DDP-4) inhibitors have anti-atherosclerotic effects. However, in the PROLOGUE study, sitagliptin failed to slow the progression of carotid intima-media thickness (CIMT) relative to conventional therapy. We conducted a post hoc analysis of the PROLOGUE study and compared the effects of sitagliptin and conventional therapy on changes in CIMT in subgroups with or without hyperuricemia. Methods: The PROLOGUE study was a randomized controlled trial of 442 patients with type 2 diabetes mellitus (T2DM). Patients were randomized to receive sitagliptin added therapy or conventional therapy. Based on the serum uric acid levels of all study populations in the PROLOGUE study, we divided them into hyperuricemia subgroup ( n = 104) and non-hyperuricemia subgroup ( n = 331). The primary outcome was changed in carotid intima-media thickness (CIMT) parameters compared with baseline during the 24 months treatment period. Results: In the hyperuricemia subgroup, compared with the conventional therapy group, the changes in the mean internal carotid artery (ICA)-IMT and max ICA-IMT at 24 months were significantly lower in the sitagliptin group [−0.233 mm, 95% confidence interval (CI) (−0.419 to 0.046), p = 0.015 and −0.325 mm, 95% CI (−0.583 to −0.068), p = 0.014], although there was no significant difference in the common carotid artery CIMT. Conclusion: The results of our analysis indicated that sitagliptin attenuated the progression of CIMT than conventional therapy in T2DM and hyperuricemia patients.


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