Hemodynamic, autonomic and baroreflex changes after one night sleep deprivation in healthy volunteers

2009 ◽  
Vol 145 (1-2) ◽  
pp. 76-80 ◽  
Author(s):  
Massimo Pagani ◽  
Paolo Pizzinelli ◽  
Anne Pavy-Le Traon ◽  
Cinzia Ferreri ◽  
Silvia Beltrami ◽  
...  
Keyword(s):  
Sleep Deprivation ◽  
Healthy Volunteers ◽  
Night Sleep

Antagonism by modafinil of the psychomotor and cognitive impairment induced by sleep-deprivation in 12 healthy volunteers

1991 ◽  
Vol 6 (2) ◽  
pp. 93-97 ◽  
Author(s):  
G Bensimon ◽  
D Benoit ◽  
L Lacomblez ◽  
E Weiller ◽  
D Warot ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Sleep Deprivation ◽  
Healthy Volunteers ◽  
Controlled Study ◽  
Long Term Memory ◽  
Double Blind ◽  
Flicker Fusion Frequency ◽  
Short And Long Term ◽  
Psychotropic Compound

SummaryModafinil is a new psychotropic compound with central α1, adrenergic-stimulant activity in animals. In the present study, its pharmacological activity in man was evaluated in the sleep-deprivation induced psychomotor and cognitive impairment paradigm. This was a double-blind placebo-controlled study involving 12 healthy volunteers. Standard psychomotor and memory tasks were used, including critical flicker fusion frequency determination (CFF), choice reaction time and short- and long-term memory evaluation. Results revealed a clear antagonism by modafinil of the psychomotor and cognitive impairment induced by sleep-deprivation in most tasks 6 h after drug administration, and marginal effects 18 h after. These results therefore support a psychostimulant activity of modafinil in man.

Impact of Built Design on Nighttime Family Presence in the Intensive Care Unit

2019 ◽  
Vol 13 (1) ◽  
pp. 106-113 ◽  
Author(s):  
Truong-Giang Huynh ◽  
Robert L. Owens ◽  
Judy E. Davidson
Keyword(s):  
Intensive Care Unit ◽  
Decision Making ◽  
Intensive Care ◽  
Sleep Deprivation ◽  
Care Team ◽  
Night Sleep ◽  
Family Presence ◽  
Design Changes ◽  
Before And After

Objective: Determine whether dedicated family space changes family presence at night in the intensive care unit (ICU). Purpose: To measure family presence at night before and after moving to an ICU with in-room family space. Background: The safeguarding phenomenon families experience may lead to the desire to sit vigil at the bedside. Lack of dedicated family sleep space may exacerbate sleep deprivation for those who wish to be present at night. Sleep deprivation decreases cognition and capacity for decision-making. Traditionally, ICU rooms have not included dedicated family areas or sleep surfaces. National recommendations include designing new hospital ICU rooms with dedicated family space. It is not known if the built design changes family presence at night. Method: Family presence was measured for 30 nights pre- and postmove to a newly built ICU with dedicated family space. The policy for open flexible family presence remained the same before and after the move. Results: There was a statistically significant increase in proportion of occupied patient rooms with visitors following the move to the new ICU designed with family space (31% difference, x2= 5.675, 95% CI [5.74, 51.29], p = .0172). Conclusions: Families utilize the space when available. Further research is needed to quantify quality and quantity of family sleep and impact on decision-making and interactions with the care team. Sleep deprivation may decrease for families who would have remained in the unit without available family space and sleep surface.

The Treatment of Psychotic Depression by Sleep Deprivation: A Replication Study

1975 ◽  
Vol 127 (3) ◽  
pp. 222-226 ◽  
Author(s):  
S. Bhanji ◽  
G. A. Roy
Keyword(s):  
Adverse Effects ◽  
Sleep Deprivation ◽  
Replication Study ◽  
Physiological Study ◽  
Psychotic Depression ◽  
Night Sleep ◽  
Single Night

SummaryA replication study of the effects of single-night sleep deprivation therapy was carried out as a preliminary to a controlled comparison with orthodox antidepressant measures. The results show that sleep deprivation therapy was acceptable to a majority of the patients studied, and was followed by an improvement in over half those who completed treatment. Adverse effects were minimal. The authors feel that further clinical and physiological study is warranted.

Impact of Night Sleep Deprivation on Oxidative Stress and Blood Pressure in Adult Volunteers

2018 ◽  
Author(s):  
Zrar Marzany ◽  
◽  
Ismail Maulood ◽  
Khabat Ali ◽  
Sivan Sayid Kareem ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Sleep Deprivation ◽  
Night Sleep ◽  
Adult Volunteers

Effects of different sleep deprivation protocols on sleep perception in healthy volunteers

2014 ◽  
Vol 15 (10) ◽  
pp. 1219-1224 ◽  
Author(s):  
Leonardo I. Goulart ◽  
Luciano R. Pinto ◽  
Michael L. Perlis ◽  
Raquel Martins ◽  
Luis Otavio Caboclo ◽  
...  
Keyword(s):  
Sleep Deprivation ◽  
Healthy Volunteers

Good night, sleep tight: The effects of sleep deprivation on spatial associative learning in zebrafish

2017 ◽  
Vol 159 ◽  
pp. 36-47 ◽  
Author(s):  
Jaquelinne Pinheiro-da-Silva ◽  
Steven Tran ◽  
Priscila Fernandes Silva ◽  
Ana Carolina Luchiari
Keyword(s):  
Sleep Deprivation ◽  
Associative Learning ◽  
Night Sleep ◽  
Good Night

Effects of Total Sleep Deprivation on Cardiovascular Parameters: An Absence of Biologically Significant Findings?

2002 ◽  
Vol 16 (2) ◽  
pp. 119-126 ◽  
Author(s):  
Elena Miró ◽  
Carmen Cano ◽  
Gualberto Buela-Casal
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Sleep Deprivation ◽  
Healthy Volunteers ◽  
Repeated Measures ◽  
Clinical Relevance ◽  
Vigilance Task ◽  
Mean Values ◽  
Total Sleep Deprivation ◽  
The Third

Abstract The present study analyzes the variations of heart rate (HR) and systolic and diastolic blood pressure (SBP and DBP) during 60 h of total sleep deprivation (TSD). All variables were evaluated every 2 h in a resting condition, during the performance of a vigilance task. Thirty healthy volunteers (15 men and 15 women) from 18 to 24 years old participated in the experiment. The analyses of variance (ANOVAS) with repeated measures showed some modifications of HR and SBP mean values mainly marked by circadian oscillations. The circadian oscillations had a smaller amplitude for SBP than for HR. HR showed a slight decrease on the second night of TSD and a slight increase on the third day of TSD. SBP decreased during the first 24 h of TSD and after that maintained its values without significant changes. DBP did not show any significant variations during TSD. In addition, there were no differences in function of gender for the TSD effect on the studied variables. All these statistically significant findings, however, seem to have no biological or clinical relevance. These aspects as well as the possible relationships between our results and activation or stress levels during TSD are discussed.

Sign in / Sign up

Export Citation Format

Share Document