Low-frequency oscillations in R–R interval and blood pressure across the continuum of cardiovascular risk

Low-frequency oscillations in arterial blood pressure (Mayer waves) and R-R interval are thought to be linked through the arterial baroreflex. To delve into this relationship, we applied low (10 mmHg) and moderate (30 mmHg) lower body negative pressure (LBNP) in 10-s cycles to 18 healthy young male subjects. They showed no change in average blood pressure with this oscillatory stimulus but did show a significant decrease in R-R interval ( P < 0.05) during both levels of LBNP. In addition, we succeeded in augmenting low-frequency blood pressure oscillations in a graded response to oscillatory LBNP level ( P < 0.05) while significantly increasing low-frequency R-R interval oscillations ( P < 0.05). However, cross-spectral coherence between these increased oscillations was highly variable across individuals and stimulus level. Although nearly all subjects showed significant coherence during basal conditions ( n = 17), only seven subjects maintained significant coherence during both levels of LBNP. These results suggest that a complex interaction of regulatory mechanisms determines the link between low-frequency oscillations and the responses to even low levels of LBNP.

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Very low frequency oscillations of heart period: relationship to respiratory activity and blood pressure in heart failure patients

Computers in Cardiology 1994 ◽

10.1109/cic.1994.470132 ◽

2002 ◽

Cited By ~ 2

Author(s):

G.D. Pinna ◽

R. Maestri ◽

A. Di Cesare ◽

M.T. La Rovere ◽

A. Mortara

Keyword(s):

Heart Failure ◽

Blood Pressure ◽

Respiratory Activity ◽

Low Frequency ◽

Heart Period ◽

Very Low Frequency ◽

Heart Failure Patients ◽

Low Frequency Oscillations

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early diagnosis of the hemodynamic regulation disorders in orthostasis

Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской академии медицинских наук ◽

10.12737/23346 ◽

2016 ◽

Vol 1 (5) ◽

pp. 30-34

Author(s):

Мартынов ◽

Ilya Martynov

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

High Frequency ◽

Low Frequency ◽

Orthostatic Test ◽

Peripheral Vascular ◽

High Frequency Oscillations ◽

Low Frequency Oscillations ◽

Vasomotor Regulation ◽

Informative Content

The article deals with the informative content of spectral analysis of heart rate variability in the assessment of the regulatory impacts on the systemic hemodynamics during orthostatic test. It was observed that the patients who suffer from neurogenic syncope already at a young age had had a decrease in low frequency oscillations, as well as a decrease in peripheral vascular resistance during the test. It allows us to make a conclusion about the sympathetic vasomotor regulation dysfunction, even before the symptoms of orthostatic hypotension were evident. The decrease in the tonic vagal effect which follows from the depression of high-frequency oscillations, makes for increasing the chronotropic function of the heart and keeps a relative sympathetic predominance in order to maintain adequate level of blood pressure

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