scholarly journals Role of Clinical Laboratory Markers of inflammation in Assessing Chronic Graft Versus Host Disease (cGVHD) Activity and Severity

2011 ◽  
Vol 17 (2) ◽  
pp. S340-S341
Author(s):  
L. Grkovic ◽  
K. Baird ◽  
S.M. Steinberg ◽  
D. Pulanic ◽  
E.W. Cowen ◽  
...  
2020 ◽  
Vol 13 (2) ◽  
pp. 141-154 ◽  
Author(s):  
Jennifer S. Whangbo ◽  
Joseph H. Antin ◽  
John Koreth

Blood ◽  
2007 ◽  
Vol 110 (1) ◽  
pp. 9-17 ◽  
Author(s):  
Ronjon Chakraverty ◽  
Megan Sykes

After allogeneic blood or bone marrow transplantation, donor T cells interact with a distorted antigen-presenting cell (APC) environment in which some, but not all, host APCs are replaced by APCs from the donor. Significantly, host APCs are required for the priming of acute graft-versus-host disease (GVHD). Donor APCs play a lesser role in the induction of acute GVHD despite their predicted capacity to cross-present host antigens. In contrast, donor APCs may play a role in perpetuating the tissue injury observed in chronic GVHD. Host APCs are also required for maximal graft-versus-leukemia responses. Recent studies have suggested potential strategies by which the continued presence of host APCs can be exploited to prime strong donor immunity to tumors without the induction of GVHD.


2021 ◽  
Vol 8 (11) ◽  
pp. e862
Author(s):  
Rodothea Amerikanou ◽  
Lorna Neill ◽  
Manar Shafat ◽  
Harriet Roddy ◽  
Harpreet Hyare ◽  
...  

2020 ◽  
Vol 26 (3) ◽  
pp. S191-S192
Author(s):  
Amandeep Salhotra ◽  
Weimin Tsai ◽  
Dongyun Yang ◽  
Sally Mokhtari ◽  
Badri Modi ◽  
...  

2008 ◽  
Vol 28 (3) ◽  
pp. 249-267 ◽  
Author(s):  
Sae Jin Oh ◽  
Ji Hyung Kim ◽  
Chang Ki Min ◽  
Doo Hyun Chung

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