Multi-organ graft-versus-host disease after nivolumab for relapsed Hodgkin lymphoma: the role of plasma exchange

2021 ◽  
Vol 8 (11) ◽  
pp. e862
Author(s):  
Rodothea Amerikanou ◽  
Lorna Neill ◽  
Manar Shafat ◽  
Harriet Roddy ◽  
Harpreet Hyare ◽  
...  
2020 ◽  
Vol 13 (2) ◽  
pp. 141-154 ◽  
Author(s):  
Jennifer S. Whangbo ◽  
Joseph H. Antin ◽  
John Koreth

Blood ◽  
2007 ◽  
Vol 110 (1) ◽  
pp. 9-17 ◽  
Author(s):  
Ronjon Chakraverty ◽  
Megan Sykes

After allogeneic blood or bone marrow transplantation, donor T cells interact with a distorted antigen-presenting cell (APC) environment in which some, but not all, host APCs are replaced by APCs from the donor. Significantly, host APCs are required for the priming of acute graft-versus-host disease (GVHD). Donor APCs play a lesser role in the induction of acute GVHD despite their predicted capacity to cross-present host antigens. In contrast, donor APCs may play a role in perpetuating the tissue injury observed in chronic GVHD. Host APCs are also required for maximal graft-versus-leukemia responses. Recent studies have suggested potential strategies by which the continued presence of host APCs can be exploited to prime strong donor immunity to tumors without the induction of GVHD.


2008 ◽  
Vol 28 (3) ◽  
pp. 249-267 ◽  
Author(s):  
Sae Jin Oh ◽  
Ji Hyung Kim ◽  
Chang Ki Min ◽  
Doo Hyun Chung

2011 ◽  
Vol 17 (2) ◽  
pp. S333 ◽  
Author(s):  
M.A. Cherry ◽  
H. Parekh ◽  
Z. Yu ◽  
M. Lerner ◽  
G. Selby ◽  
...  

2015 ◽  
Vol 21 (5) ◽  
pp. 821-828 ◽  
Author(s):  
Joëlle Gregoire-Gauthier ◽  
François Fontaine ◽  
Lionel Benchimol ◽  
Simon Nicoletti ◽  
Silvia Selleri ◽  
...  

2011 ◽  
Vol 52 (10) ◽  
pp. 1844-1856 ◽  
Author(s):  
Stephen Murphy ◽  
Vu H. Nguyen

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