scholarly journals Allogeneic Hematopoietic Cell Transplantation with Full-Intensity Conditioning for Adult Acute Lymphoblastic Leukemia: Results from a Single Center, 1998-2006

2011 ◽  
Vol 17 (8) ◽  
pp. 1187-1195 ◽  
Author(s):  
Kristine Doney ◽  
Ted A. Gooley ◽  
H. Joachim Deeg ◽  
Mary E.D. Flowers ◽  
Rainer Storb ◽  
...  
Author(s):  
Joshua Rosenblatt ◽  
Annie Leung ◽  
Emily Baneman ◽  
Risa Fuller ◽  
Sarah Taimur ◽  
...  

Abstract A patient with relapsed/refractory B-cell acute lymphoblastic leukemia developed babesiosis prior to allogeneic hematopoietic cell transplantation while on atovaquone for Pneumocystis jirovecii pneumonia prophylaxis. Despite receiving a prolonged course of atovaquone and azithromycin until whole blood Babesia microti DNA was no longer detected by polymerase chain reaction, her post-transplant course was complicated by relapsed babesiosis. We investigate the potential host and parasite characteristics causing relapsing/persistent infection.


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