scholarly journals Busulfan-Based Allogeneic Hematopoietic Cell Transplantation with Various Donor Type Including Haploidentical Familial Mismatched Donor as Post-Remission Therapy in Adult Acute Lymphoblastic Leukemia

2016 ◽  
Vol 22 (3) ◽  
pp. S331-S332
Author(s):  
Dae-Young Kim ◽  
Han-Seung Park ◽  
Eunji Choi ◽  
Je-Hwan Lee ◽  
Jung-Hee Lee ◽  
...  
Author(s):  
Joshua Rosenblatt ◽  
Annie Leung ◽  
Emily Baneman ◽  
Risa Fuller ◽  
Sarah Taimur ◽  
...  

Abstract A patient with relapsed/refractory B-cell acute lymphoblastic leukemia developed babesiosis prior to allogeneic hematopoietic cell transplantation while on atovaquone for Pneumocystis jirovecii pneumonia prophylaxis. Despite receiving a prolonged course of atovaquone and azithromycin until whole blood Babesia microti DNA was no longer detected by polymerase chain reaction, her post-transplant course was complicated by relapsed babesiosis. We investigate the potential host and parasite characteristics causing relapsing/persistent infection.


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