scholarly journals Allogeneic Hematopoietic Cell Transplantation for Adult Acute Lymphoblastic Leukemia: Significant Increase in Survival in the Post-Targeted Immunotherapy Era

2020 ◽  
Vol 26 (3) ◽  
pp. S106
Author(s):  
Lori Muffly ◽  
Sally Arai ◽  
Laura Johnston ◽  
Robert Lowsky ◽  
Everett H. Meyer ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Lymphoblastic Leukemia ◽  
Hematopoietic Cell ◽  
Allogeneic Hematopoietic Cell Transplantation ◽  
Adult Acute Lymphoblastic Leukemia ◽  
Targeted Immunotherapy

scholarly journals Relapsed Babesia microti Infection following Allogeneic Hematopoietic Cell Transplantation in a Patient with B-Cell Acute Lymphoblastic Leukemia: Case Report and Review of the Literature

2021 ◽  
Author(s):  
Joshua Rosenblatt ◽  
Annie Leung ◽  
Emily Baneman ◽  
Risa Fuller ◽  
Sarah Taimur ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
B Cell ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Lymphoblastic Leukemia ◽  
Hematopoietic Cell ◽  
Allogeneic Hematopoietic Cell Transplantation ◽  
Babesia Microti ◽  
Pneumocystis Jirovecii Pneumonia ◽  
Cell Acute Lymphoblastic Leukemia

Abstract A patient with relapsed/refractory B-cell acute lymphoblastic leukemia developed babesiosis prior to allogeneic hematopoietic cell transplantation while on atovaquone for Pneumocystis jirovecii pneumonia prophylaxis. Despite receiving a prolonged course of atovaquone and azithromycin until whole blood Babesia microti DNA was no longer detected by polymerase chain reaction, her post-transplant course was complicated by relapsed babesiosis. We investigate the potential host and parasite characteristics causing relapsing/persistent infection.

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