scholarly journals The Impact of Donor Type on Outcomes and Cost of Allogeneic Hematopoietic Cell Transplantation for Pediatric Leukemia: A Merged Center for International Blood and Marrow Transplant Research and Pediatric Health Information System Analysis

2020 ◽  
Vol 26 (9) ◽  
pp. 1747-1756 ◽  
Author(s):  
Staci D. Arnold ◽  
Ruta Brazauskas ◽  
Naya He ◽  
Yimei Li ◽  
Matt Hall ◽  
...  
Author(s):  
Deepa L. N. ◽  
Gopinath D.

Background: Primary aim of health information system is, using it in decision-making. Not many systematic studies on actual status of health information system are available.  So this study was undertaken to evaluate the current status of Health Information System (HIS) at the primary level in relation to selective components of Reproductive and Child Health (RCH) Programme and to determine its utilization for identification of problem and decision making at that level.Methods:Cross sectional study done in Bangalore Urban District. HIS was analyzed for completeness, timeliness and utilization. Monthly reports of previous 3 months from PHCs were looked for completeness and timeliness.  Utilization of information was assessed by interviewing the medical officers of 4 PHCs for actions they intend to take for modifying the performance; prior to and also after providing them with analyzed information of the available data (customization of data). Both these were compared for differences and specificity of responses. For customization of the data, sub center reports were reviewed and few beneficiaries were interviewed.Results: 85% of the reporting formats were incompletely filled. It was observed an increase in number of medical officers giving more specific actions such as review in monthly meeting, ask explanation by specific sub-center health worker for not giving follow up care to improve the performance than the responses which were more general prior to receiving the customized data. It shows that MOs are not utilizing the available health information for identification of problem or to make decisions.Conclusions:This study showed that medical officers are signing the monthly reports prepared by health workers, without actually using the information at least to identify the problem as it was seen that coverage in one sub-centre was consistently low for all the three months but didn’t focus their actions towards that sub center.  


2014 ◽  
Vol 47 (4) ◽  
pp. 147-154
Author(s):  
Václav Kouba

Abstract There is no systematic monitoring of global spreading of pathogens through international trade carried out by any organisation regulating world-wide trade in animals and their products. A critical evaluation of the impact of international trade provisions on global pathogen spread is missing as well. Data related to this kind of analysis are no more internationally collected. However, information on animal infection occurrence is of paramount importance for decision-making on animal health import conditions based on pathogen introduction risk assessment considering first of all the epizootiological situation in exporting countries. Actual international animal health information system covers just a small part of known animal infections and provides much less information on their occurrence and epizootiological characteristics than before (except for a few selected emergency infections). It provides the importing countries zero or insufficient data for objective risk assessment to avoid pathogen introduction through international trade. Illegal export/import is not recorded in any information system. The globalisation era trade requires much more efficient information system, including monitoring of global spread of pathogenic microflora through trade, as the basis for more effective international preventive and control anti-epizootic measures. There is an urgent need to re-establish animal health information system within the United Nations Organization as its inseparable component for follow-up execution of animal health technical assistance and global anti-epizootic programmes.


Blood ◽  
2012 ◽  
Vol 119 (1) ◽  
pp. 296-307 ◽  
Author(s):  
Madan Jagasia ◽  
Mukta Arora ◽  
Mary E. D. Flowers ◽  
Nelson J. Chao ◽  
Philip L. McCarthy ◽  
...  

Abstract Risk factors for acute GVHD (AGVHD), overall survival, and transplant-related mortality were evaluated in adults receiving allogeneic hematopoietic cell transplants (1999-2005) from HLA-identical sibling donors (SDs; n = 3191) or unrelated donors (URDs; n = 2370) and reported to the Center for International Blood and Marrow Transplant Research, Minneapolis, MN. To understand the impact of transplant regimen on AGVHD risk, 6 treatment categories were evaluated: (1) myeloablative conditioning (MA) with total body irradiation (TBI) + PBSCs, (2) MA + TBI + BM, (3) MA + nonTBI + PBSCs, (4) MA + nonTBI + BM, (5) reduced intensity conditioning (RIC) + PBSCs, and (6) RIC + BM. The cumulative incidences of grades B-D AGVHD were 39% (95% confidence interval [CI], 37%-41%) in the SD cohort and 59% (95% CI, 57%-61%) in the URD cohort. Patients receiving SD transplants with MA + nonTBI + BM and RIC + PBSCs had significantly lower risks of grades B-D AGVHD than patients in other treatment categories. Those receiving URD transplants with MA + TBI + BM, MA + nonTBI + BM, RIC + BM, or RIC + PBSCs had lower risks of grades B-D AGVHD than those in other treatment categories. The 5-year probabilities of survival were 46% (95% CI, 44%-49%) with SD transplants and 33% (95% CI, 31%-35%) with URD transplants. Conditioning intensity, TBI and graft source have a combined effect on risk of AGVHD that must be considered in deciding on a treatment strategy for individual patients.


2018 ◽  
Vol 8 (10) ◽  
Author(s):  
Keith Horvath ◽  
◽  
Patricia Sengstack ◽  
Frank Opelka ◽  
Andrea Borondy Kitts ◽  
...  

Cardiology ◽  
2021 ◽  
pp. 1-7
Author(s):  
Aziez Ahmed ◽  
Parthak Prodhan ◽  
Beverly J. Spray ◽  
Elijah H. Bolin

Introduction: Tachydysrhythmias (TDS) frequently occur after complete repair of tetralogy of Fallot (TOF). However, not much is known about the effect of TDS on morbidity and mortality after TOF repair. We sought to assess the associations between TDS and mortality and morbidity after repair of TOF using a multicentre database. Materials and Methods: We identified all children aged 0–5 years in the Pediatric Health Information System who underwent TOF repair between 2004 and 2015. Codes for TDS were used to identify cases. Outcome variables were inpatient mortality and total length of stay (LOS). Univariate and multiple logistic and linear regression analyses were used to identify the effects of multiple risk factors, including TDS, on mortality and LOS. Results: A total of 7,749 patients met inclusion criteria, of which 1,493 (19%) had codes for TDS. There was no association between TDS and inpatient mortality. However, TDS were associated with 1.1 days longer LOS and accounted for 2% of the variation observed in LOS. Conclusion: After complete repair of TOF, TDS were not associated with mortality and appeared to have only a modest effect on LOS.


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