Executive functioning-specific behavioral impairments in a rat model of human third trimester binge drinking implicate prefrontal-thalamo-hippocampal circuitry in Fetal Alcohol Spectrum Disorders

2021 ◽  
pp. 113208
Author(s):  
Z.H. Gursky ◽  
L.M. Savage ◽  
A.Y. Klintsova
2014 ◽  
Vol 21 (6) ◽  
pp. 716-731 ◽  
Author(s):  
Anita J. Fuglestad ◽  
Marisa L. Whitley ◽  
Stephanie M. Carlson ◽  
Christopher J. Boys ◽  
Judith K. Eckerle ◽  
...  

2014 ◽  
Vol 21 (2) ◽  
pp. 191-209 ◽  
Author(s):  
Kelly Nash ◽  
Sara Stevens ◽  
Rachel Greenbaum ◽  
Judith Weiner ◽  
Gideon Koren ◽  
...  

2016 ◽  
Vol 23 (14) ◽  
pp. 1801-1815
Author(s):  
Jennifer E. Khoury ◽  
Karen Milligan

Objective: Fetal alcohol spectrum disorders (FASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are associated with a range of neurocognitive impairments. Executive functioning deficits are a hallmark feature of both disorders. Method: The present meta-analysis was undertaken to disentangle the behavioral phenotype of FASD and ADHD by quantitatively differentiating executive functioning differences between these two groups. The current meta-analysis reviews 15 studies comparing children and adolescents with FASD and ADHD to typically developing (TD) samples, on a variety of executive function measures. Results: Results indicate that when compared with TD samples, FASD and ADHD samples demonstrate significant executive function deficits ( d = 0.82 and d = 0.55, respectively). In addition, FASD samples experience significantly greater deficits when compared with ADHD samples ( d = 0.25). Results were moderated by IQ and socioeconomic status. Conclusion: These findings further our understanding of the cognitive differences between FASD and ADHD samples and have the potential to influence future basic research, assessment, and intervention.


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