Dual sphingosine kinase inhibitor SKI-II enhances sensitivity to 5-fluorouracil in hepatocellular carcinoma cells via suppression of osteopontin and FAK/IGF-1R signalling

2017 ◽  
Vol 487 (4) ◽  
pp. 782-788 ◽  
Author(s):  
Petra Grbčić ◽  
Ivana Tomljanović ◽  
Marko Klobučar ◽  
Sandra Kraljević Pavelić ◽  
Ksenija Lučin ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Kinase Inhibitor ◽  
Sphingosine Kinase ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells ◽  
Sphingosine Kinase Inhibitor

scholarly journals Identification of sphingosine kinase 1 (SphK1) as a primary target of icaritin in hepatocellular carcinoma cells

Oncotarget ◽  
2017 ◽  
Vol 8 (14) ◽  
pp. 22800-22810 ◽  
Author(s):  
Pei-Hua Lu ◽  
Min-Bin Chen ◽  
Yuan-Yuan Liu ◽  
Mian-Hua Wu ◽  
Wen-Ting Li ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Sphingosine Kinase ◽  
Carcinoma Cells ◽  
Sphingosine Kinase 1 ◽  
Primary Target ◽  
Hepatocellular Carcinoma Cells
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