BCR-ABL tyrosine kinase inhibition induces metabolic vulnerability by preventing the integrated stress response in K562 cells

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2018.09.032 ◽

2018 ◽

Vol 504 (4) ◽

pp. 721-726

Author(s):

Yu Kato ◽

Kazuhiro Kunimasa ◽

Yoshikazu Sugimoto ◽

Akihiro Tomida

Keyword(s):

Stress Response ◽

Tyrosine Kinase ◽

Integrated Stress Response ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

Abl Tyrosine Kinase

Download Full-text

Abstract 217: BCR-ABL tyrosine kinase inhibition combined with a novel pan BCL2 family inhibitor abrogates leukemia stem cell survival in a niche-dependent manner.

10.1158/1538-7445.am2013-217 ◽

2013 ◽

Author(s):

Wenxue Ma ◽

Janine Low-Marchelli ◽

Heather S. Leu ◽

Angela Court Recart ◽

Jun Wei ◽

...

Keyword(s):

Stem Cell ◽

Tyrosine Kinase ◽

Cell Survival ◽

Dependent Manner ◽

Leukemia Stem Cell ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

Bcl2 Family ◽

Abl Tyrosine Kinase ◽

Stem Cell Survival

Download Full-text

Novel α-Aminophosphonates of imatinib Intermediate: Synthesis, anticancer Activity, human Abl tyrosine kinase Inhibition, ADME and toxicity prediction

Bioorganic Chemistry ◽

10.1016/j.bioorg.2021.104718 ◽

2021 ◽

Vol 109 ◽

pp. 104718

Author(s):

Saikiran Aita ◽

Vishnu Nayak Badavath ◽

Mohan Gundluru ◽

Murali Sudileti ◽

Bakthavatchala Reddy Nemallapudi ◽

...

Keyword(s):

Tyrosine Kinase ◽

Anticancer Activity ◽

Toxicity Prediction ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

Abl Tyrosine Kinase

Download Full-text

Bruton's tyrosine kinase inhibition induces rewiring of proximal and distal B‐cell receptor signaling in mice

European Journal of Immunology ◽

10.1002/eji.202048968 ◽

2021 ◽

Author(s):

Jasper Rip ◽

Marjolein J.W. Bruijn ◽

Stefan F.H. Neys ◽

Simar Pal Singh ◽

Jonas Willar ◽

...

Keyword(s):

Tyrosine Kinase ◽

B Cell ◽

Cell Receptor ◽

B Cell Receptor ◽

Receptor Signaling ◽

Bruton's Tyrosine Kinase ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

Download Full-text

NLRP3 inflammasome and bruton tyrosine kinase inhibition interferes with upregulated platelet aggregation and in vitro thrombus formation in sickle cell mice

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2021.03.115 ◽

2021 ◽

Vol 555 ◽

pp. 196-201

Author(s):

Sebastian Vogel ◽

Sayuri Kamimura ◽

Taruna Arora ◽

Meghann L. Smith ◽

Luis E.F. Almeida ◽

...

Keyword(s):

Platelet Aggregation ◽

Tyrosine Kinase ◽

Sickle Cell ◽

Nlrp3 Inflammasome ◽

Thrombus Formation ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

Bruton Tyrosine Kinase

Download Full-text

Antiproliferative effects of EGFR tyrosine kinase inhibition and radiation-induced genotoxic injury are attenuated by adhesion to fibronectin

Radiotherapy and Oncology ◽

10.1016/j.radonc.2006.07.028 ◽

2006 ◽

Vol 80 (2) ◽

pp. 178-184 ◽

Author(s):

Iris Eke ◽

Veit Sandfort ◽

Antje Mischkus ◽

Michael Baumann ◽

Nils Cordes

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibition ◽

Antiproliferative Effects ◽

Tyrosine Kinase Inhibition ◽

Egfr Tyrosine Kinase ◽

Radiation Induced

Download Full-text

Abstract LB198: Inhibition of the RAC Activator VAV3 by the small molecule IODVA1 impedes RAC signaling & overcomes resistance to tyrosine kinase inhibition in lymphoblastic leukemia

10.1158/1538-7445.am2021-lb198 ◽

2021 ◽

Author(s):

Nicolas N. Nassar ◽

Shailaja Hegde ◽

Kark Wunderlich ◽

Yuan Lin ◽

Reza Ahmadian ◽

...

Keyword(s):

Tyrosine Kinase ◽

Small Molecule ◽

Lymphoblastic Leukemia ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition

Download Full-text

Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats

Kidney International ◽

10.1111/j.1523-1755.2004.00952.x ◽

2004 ◽

Vol 66 (5) ◽

pp. 1766-1773 ◽

Author(s):

Vicente E. Torres ◽

William E. Sweeney ◽

Xiaofang Wang ◽

Q.I. Qian ◽

Peter C. Harris ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Growth Factor Receptor ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

Epidermal Growth

Download Full-text

Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis

Journal of Neuroinflammation ◽

10.1186/s12974-016-0620-9 ◽

2016 ◽

Vol 13 (1) ◽

Author(s):

Emiliano Trias ◽

Sofía Ibarburu ◽

Romina Barreto-Núñez ◽

Joël Babdor ◽

Thiago T. Maciel ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Tyrosine Kinase ◽

Disease Progression ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

Lateral Sclerosis

Download Full-text

Oral melanosis after tyrosine kinase inhibition with Imatinib for chronic myelogenous leukemia: Report of a case and review of the literature

Dermatology Online Journal ◽

10.5070/d3498194bx ◽

2011 ◽

Vol 17 (5) ◽

Author(s):

Michelle Wong ◽

Shachar Sade ◽

Melanie Gilbert ◽

Hagen B E Klieb

Keyword(s):

Tyrosine Kinase ◽

Chronic Myelogenous Leukemia ◽

Myelogenous Leukemia ◽

Review Of The Literature ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition

Download Full-text

Correction: Cytotoxic trichothecene-type sesquiterpenes from the sponge-derived fungus Stachybotrys chartarum with tyrosine kinase inhibition

RSC Advances ◽

10.1039/c9ra90052g ◽

2019 ◽

Vol 9 (37) ◽

pp. 21518-21518

Author(s):

Yong Li ◽

Dong Liu ◽

Zhongbin Cheng ◽

Peter Proksch ◽

Wenhan Lin

Keyword(s):

Tyrosine Kinase ◽

Stachybotrys Chartarum ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition

Correction for ‘Cytotoxic trichothecene-type sesquiterpenes from the sponge-derived fungus Stachybotrys chartarum with tyrosine kinase inhibition’ by Yong Li et al., RSC Adv., 2017, 7, 7259–7267.

Download Full-text