Role of early case detection by screening relatives of patients with HFE-associated hereditary haemochromatosis

2005 ◽  
Vol 18 (2) ◽  
pp. 221-234 ◽  
Author(s):  
L POWELL ◽  
J DIXON ◽  
D HEWETT
Keyword(s):  
Case Detection ◽  
Hereditary Haemochromatosis ◽  
Early Case ◽  
Early Case Detection

scholarly journals Preliminary report of an autochthonous chikungunya outbreak in France, July to September 2017

2017 ◽  
Vol 22 (39) ◽  
Author(s):  
Clémentine Calba ◽  
Mathilde Guerbois-Galla ◽  
Florian Franke ◽  
Charles Jeannin ◽  
Michelle Auzet-Caillaud ◽  
...  
Keyword(s):  
South African ◽  
Preliminary Report ◽  
Chikungunya Virus ◽  
Adaptive Mutation ◽  
Case Detection ◽  
African Region ◽  
East Central ◽  
Early Case ◽  
Central South ◽  
Early Case Detection

In August 2017, an autochthonous chikungunya case was reported in south-east France. By mid-September, eight additional autochthonous cases were found in the index case’s neighbourhood, where the chikungunya virus vector Aedes albopictus was observed. Genomic characterisation identified an East-Central South African (ECSA) lineage strain, probably from the Central African region and carrying an adaptive mutation facilitating transmission by Ae. albopictus. The event confirms we need early case detection and response to contain chikungunya in Europe.

scholarly journals Tool for estimating the probability of having COVID-19 with one or more negative RT-PCR results

2021 ◽  
Author(s):  
Alejandro Jara ◽  
Eduardo A. Undurraga ◽  
Rafael Araos
Keyword(s):  
Gold Standard ◽  
Case Detection ◽  
Rt Pcr ◽  
False Negatives ◽  
Online Tool ◽  
Early Case ◽  
User Friendly ◽  
Early Case Detection

AbstractEarly case detection and isolation of infected individuals are critical to controlling COVID-19. RT-PCR is considered the diagnosis gold standard, but false-negatives occur. Based on previous work, we built a user-friendly online tool to estimate the probability of having COVID-19 with negative RT-PCR results and thus avoid preventable SARS-CoV-2 transmission.

Nutritional status and morbidity profile of children with leprosy contact in a rural community

2020 ◽  
Vol 50 (4) ◽  
pp. 311-317
Author(s):  
Yegnaraman Venkatakrishnan ◽  
Pugazhenthan Thangaraju ◽  
Sathya Jeganathan ◽  
Suresh K Sankaran ◽  
Rajkumar Kannan
Keyword(s):  
Nutritional Status ◽  
Common Finding ◽  
Effective Strategies ◽  
Interview Method ◽  
Status Assessment ◽  
Community Transmission ◽  
Early Case ◽  
Regular Contact ◽  
Early Case Detection

An observational pilot study was conducted to assess the nutritional status and morbidity profile of childhood contacts of leprosy in an endemic area (Chengalpattu) in India. A total of 70 such children were included in the study. Sociodemographic data were collected using a one-to-one interview method and the children were evaluated by dermatologists qualified in paediatric leprosy. The obtained data were computed. Three children were diagnosed to have leprosy through this study. Nutritional status assessment in these children demonstrated malnutrition, a common finding. Regular contact screening of children in endemic areas for early case detection, disability prevention and thereby prevention of community transmission is mandatory. Further research is needed concerning the role of malnutrition in children and its relation to morbidity in leprosy. The closeness and duration of contact of leprosy is also an important risk factor. Effective strategies to diagnose subclinical infection are needed.

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