Directing neural differentiation of mesenchymal stem cells by carboxylated multiwalled carbon nanotubes

Biomaterials ◽  
2013 ◽  
Vol 34 (21) ◽  
pp. 4936-4944 ◽  
Author(s):  
Yu-Shuan Chen ◽  
Ging-Ho Hsiue
2019 ◽  
Vol 21 (8) ◽  
Author(s):  
Jose G. Munguia-Lopez ◽  
Rodrigo Juarez ◽  
Emilio Muñoz-Sandoval ◽  
Marco A. Kalixto-Sanchez ◽  
Joseph Matthew Kinsella ◽  
...  

Nanomedicine ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. 793-808 ◽  
Author(s):  
Mohamed R Berber ◽  
Hoda Elkhenany ◽  
Inas H Hafez ◽  
Ahmed El-Badawy ◽  
Mohamed Essawy ◽  
...  

Aim: Therapeutically targeting cancer stem cells (CSCs), which play a role in tumor initiation and relapse, remains challenging. Materials & methods: Novel-formulated platinum nanoparticles (Pt-NPs) supported on polybenzimidazole (PBI)-functionalized polymers and multiwalled carbon nanotubes (MWCNT) were prepared and their effect on CSCs was evaluated. Results: Pt-NPs showed homogenous distribution on the surface of MWCNT/PBI composites, with very narrow particle size. MWCNT/PBI/Pt-NPs resulted in a dramatic decrease in the proliferation rate of CSCs but not bone marrow mesenchymal stem cells (BM-MSCs). Quantitative gene expression analysis revealed that MWCNT/PBI/Pt had a significant inhibitory effect on the epithelial-mesenchymal transition and cell cycle markers of CSCs. Conclusion: MWCNT/PBI/Pt exhibited a specific cytotoxic effect on breast CSCs but not on adult stem cells.


2012 ◽  
Vol 2 (6) ◽  
pp. 166-168 ◽  
Author(s):  
Dr.T.Ch.Madhavi Dr.T.Ch.Madhavi ◽  
◽  
Pavithra.P Pavithra.P ◽  
Sushmita Baban Singh Sushmita Baban Singh ◽  
S.B.Vamsi Raj S.B.Vamsi Raj ◽  
...  

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