Poly(2-ethyl-2-oxazoline) conjugates with doxorubicin for cancer therapy: In vitro and in vivo evaluation and direct comparison to poly[N-(2-hydroxypropyl)methacrylamide] analogues

Biomaterials ◽  
2017 ◽  
Vol 146 ◽  
pp. 1-12 ◽  
Author(s):  
Ondrej Sedlacek ◽  
Bryn D. Monnery ◽  
Jana Mattova ◽  
Jan Kucka ◽  
Jiri Panek ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
In Vivo Evaluation ◽  
Hydroxypropyl Methacrylamide

N-(2-Hydroxypropyl)methacrylamide Copolymer−6-(3-Aminopropyl)-ellipticine Conjugates. Synthesis, in Vitro, and Preliminary in Vivo Evaluation

2001 ◽  
Vol 12 (5) ◽  
pp. 711-718 ◽  
Author(s):  
F. Searle ◽  
S. Gac-Breton ◽  
R. Keane ◽  
S. Dimitrijevic ◽  
S. Brocchini ◽  
...  
Keyword(s):  
In Vivo Evaluation ◽  
Hydroxypropyl Methacrylamide

Novel folate-targeted docetaxel-loaded nanoparticles for tumour targeting: in vitro and in vivo evaluation

RSC Advances ◽  
2016 ◽  
Vol 6 (69) ◽  
pp. 64306-64314 ◽  
Author(s):  
M. H. Han ◽  
Z. T. Li ◽  
D. D. Bi ◽  
Y. F. Guo ◽  
H. X. Kuang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Folic Acid ◽  
Cancer Therapy ◽  
Targeted Delivery ◽  
Tumour Targeting ◽  
Breast Cancer Therapy ◽  
In Vivo Evaluation ◽  
Targeted Delivery System

Cholesterol-PEG1000-FA (folic acid) was synthesized as a stabilizer to encapsulate DTX, for the construction of a promising targeted delivery system for breast cancer therapy.

scholarly journals In Vitro and In Vivo Evaluation of PEGylated Starch-Coated Iron Oxide Nanoparticles for Enhanced Photothermal Cancer Therapy

Pharmaceutics ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 871
Author(s):  
Reeju Amatya ◽  
Seungmi Hwang ◽  
Taehoon Park ◽  
Kyoung Ah Min ◽  
Meong Cheol Shin
Keyword(s):  
Iron Oxide ◽  
Cancer Therapy ◽  
Iron Oxide Nanoparticles ◽  
Research Field ◽  
Oxide Nanoparticles ◽  
In Vivo Evaluation ◽  
Study Results ◽  
Tumor Accumulation

Iron oxide nanoparticles (IONPs) possess versatile utility in cancer theranostics, thus, they have drawn enormous interest in the cancer research field. Herein, we prepared polyethylene glycol (PEG)-conjugated and starch-coated IONPs (“PEG–starch–IONPs”), and assessed their applicability for photothermal treatment (PTT) of cancer. The prepared PEG–starch–IONPs were investigated for their physical properties by transmission electron microscopy (TEM), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, and dynamic light scattering (DLS). The pharmacokinetic study results showed a significant extension in the plasma half-life by PEGylation, which led to a markedly increased (5.7-fold) tumor accumulation. When PEG–starch–IONPs were evaluated for their photothermal activity, notably, they displayed marked and reproducible heating effects selectively on the tumor site with laser irradiation. Lastly, efficacy studies demonstrated that PEG–starch–IONPs-based PTT may be a promising mode of cancer therapy.

In-vitro and in-vivo evaluation of pH-responsive polymeric micelles in a photodynamic cancer therapy model

2001 ◽  
Vol 53 (2) ◽  
pp. 155-166 ◽  
Author(s):  
J. Taillefer ◽  
N. Brasseur ◽  
J. E. van Lier ◽  
V. Lenaerts ◽  
D. Le Garrec ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Polymeric Micelles ◽  
Ph Responsive ◽  
In Vivo Evaluation ◽  
Photodynamic Cancer Therapy ◽  
Therapy Model
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