Signal amplification of electrochemical immunosensor for the detection of human serum IgG using double-codified nanosilica particles as labels

2009 ◽  
Vol 24 (7) ◽  
pp. 2246-2249 ◽  
Author(s):  
Zhaoyang Zhong ◽  
Mengxia Li ◽  
Debing Xiang ◽  
Nan Dai ◽  
Ying Qing ◽  
...  
Keyword(s):  
Human Serum ◽  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Serum Igg ◽  
Nanosilica Particles

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

A new enzyme-free quadratic SERS signal amplification approach for circulating microRNA detection in human serum

2015 ◽  
Vol 51 (90) ◽  
pp. 16271-16274 ◽  
Author(s):  
Jing Zheng ◽  
Dandan Ma ◽  
Muling Shi ◽  
Junhui Bai ◽  
Yinhui Li ◽  
...  
Keyword(s):  
Human Serum ◽  
Signal Amplification ◽  
Circulating Microrna ◽  
Ultrasensitive Detection ◽  
Circulating Mirna ◽  
Sers Signal ◽  
Microrna Detection

In this communication, we proposed a new enzyme-free quadratic SERS signal amplification approach for the ultrasensitive detection of circulating miRNA in human serum.

A novel electrochemical immunosensor based on dual signal amplification of gold nanoparticles and telomerase extension reaction

2014 ◽  
Vol 6 (7) ◽  
pp. 2221-2226 ◽  
Author(s):  
Xiao-Yan Li ◽  
Zi Yi ◽  
Hao Tang ◽  
Xia Chu ◽  
Ru-Qin Yu
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Highly Sensitive ◽  
Dual Signal Amplification

Highly sensitive electrochemical immune analysis was achieved based on dual signal amplification of AuNPs and telomerase extension reaction.

Structural Analysis of an N-Glycan with “β1−4 Bisecting Branch” from Human Serum IgG by Negative-Ion MSnSpectral Matching and Exoglycosidase Digestion

2005 ◽  
Vol 77 (18) ◽  
pp. 6062-6068 ◽  
Author(s):  
Yasuhiro Takegawa ◽  
Kisaburo Deguchi ◽  
Hiroaki Nakagawa ◽  
Shin-Ichiro Nishimura
Keyword(s):  
Structural Analysis ◽  
Human Serum ◽  
Negative Ion ◽  
Serum Igg
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