Development of luminol-N-hydroxyphthalimide chemiluminescence system for highly selective and sensitive detection of superoxide dismutase, uric acid and Co2+

2018 ◽  
Vol 99 ◽  
pp. 519-524 ◽  
Author(s):  
Muhammad Saqib ◽  
Liming Qi ◽  
Pan Hui ◽  
Anaclet Nsabimana ◽  
Mohamed Ibrahim Halawa ◽  
...  
Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2512
Author(s):  
Mariangela Rondanelli ◽  
Niccolò Miraglia ◽  
Pietro Putignano ◽  
Ignazio Castagliuolo ◽  
Paola Brun ◽  
...  

In animals it has been demonstrated that Saccharomyces boulardii and Superoxide Dismutase (SOD) decrease low-grade inflammation and that S. boulardii can also decrease adiposity. The purpose of this study was to evaluate the effect of a 60-day S. boulardii and SOD supplementation on circulating markers of inflammation, body composition, hunger sensation, pro/antioxidant ratio, hormonal, lipid profile, glucose, insulin and HOMA-IR, in obese adults (BMI 30–35 kg/m2). Twenty-five obese adults were randomly assigned to intervention (8/4 women/men, 57 ± 8 years) or Placebo (9/4 women/men, 50 ± 9 years). Intervention group showed a statistically significant (p < 0.05) decrease of body weight, BMI, fat mass, insulin, HOMA Index and uric acid. Patients in intervention and control groups showed a significant decrease (p < 0.05) of GLP-1. Intervention group showed an increase (p < 0.05) of Vitamin D as well. In conclusion, the 60-day S. boulardii-SOD supplementation in obese subjects determined a significant weight loss with consequent decrease on fat mass, with preservation of fat free mass. The decrease of HOMA index and uric acid, produced additional benefits in obesity management. The observed increase in vitamin D levels in treated group requires further investigation.


Author(s):  
M. Verma ◽  
Tania K. Naqvi ◽  
Santosh K. Tripathi ◽  
Manish M. Kulkarni ◽  
N. Eswara Prasad ◽  
...  

2019 ◽  
Vol 38 (2) ◽  
pp. 217-224 ◽  
Author(s):  
Yiran Yang ◽  
Yu Song ◽  
Xiangjie Bo ◽  
Jihong Min ◽  
On Shun Pak ◽  
...  

2019 ◽  
Vol 14 ◽  
pp. 545-552
Author(s):  
T. Dhanasekaran ◽  
A. Padmanaban ◽  
G. Gnanamoorthy ◽  
S. Praveen Kumar ◽  
A. Stephen ◽  
...  

2009 ◽  
Vol 19 (5) ◽  
pp. 443-456 ◽  
Author(s):  
Vitor Teixeira ◽  
Hugo Valente ◽  
Susana Casal ◽  
Franklim Marques ◽  
Pedro Moreira

Strenuous physical activity is known to generate reactive oxygen species to a point that can exceed the antioxidant defense system and lead to oxidative stress. Dietary intake of antioxidants, plasma enzymatic (superoxide dismutase, glutathione reductase [Gr], and glutathione peroxidase [GPx]) activities, nonenzymatic (total antioxidant status [TAS], uric acid, α-tocopherol, retinol, α-carotene, β-carotene, lycopene, and lutein + zeaxanthin) antioxidants, and markers of lipid peroxidation (thiobarbituricacid-reactive substances [TBARS]) and muscle damage (creatine kinase [CK]) were measured in 17 elite male kayakers and canoeists under resting conditions and in an equal number of age- and sex-matched sedentary individuals. Athletes showed increased plasma values of α-tocopherol (p = .037), α-carotene (p = .003), β-carotene (p = .007), and superoxide dismutase activity (p = .002) and a lower TAS level (p = .030). Antioxidant intake (α-tocopherol, vitamin C, and β-carotene) and plasmatic GPx, Gr, lycopene, lutein + zeaxanthin, retinol, and uric acid levels were similar in both groups. Nevertheless, TBARS (p < .001) and CK (p = .011) levels were found to be significantly higher in the kayakers and canoeists. This work suggests that despite the enhanced levels of antioxidants, athletes undergoing regular strenuous exercise exhibited more oxidative stress than sedentary controls.


2019 ◽  
Vol 91 (4) ◽  
pp. 3070-3077 ◽  
Author(s):  
Muhammad Saqib ◽  
Shahida Bashir ◽  
Haijuan Li ◽  
ShanShan Wang ◽  
Yongdong Jin

2020 ◽  
Vol 31 (4) ◽  
pp. 3549-3556 ◽  
Author(s):  
Xinrui Guo ◽  
Hongyan Yue ◽  
Shuo Huang ◽  
Xin Gao ◽  
Yingyi Ma ◽  
...  

2020 ◽  
Vol 9 (4) ◽  
pp. 976 ◽  
Author(s):  
Barbara Choromańska ◽  
Piotr Myśliwiec ◽  
Magdalena Łuba ◽  
Piotr Wojskowicz ◽  
Jacek Dadan ◽  
...  

This is the first study to evaluate both the antioxidant barrier, glutathione metabolism, and oxidative damage to proteins and lipids in morbidly obese patients undergoing bariatric treatment. The study included 65 patients with class 3 obesity divided into two subgroups: morbidly obese patients without metabolic syndrome (OB) and obese patients with metabolic syndrome (OB + MS). Blood samples were collected before surgery as well as one, three, six, and twelve months after the bariatric treatment. Superoxide dismutase and reduced glutathione (GSH) were significantly decreased, whereas glutathione reductase and uric acid were enhanced in morbidly obese patients before bariatric surgery as compared to lean control. Moreover, in the OB group, we observed the increase of superoxide dismutase (SOD) and the decrease of uric acid (UA) after the bariatric treatment; however, these changes were not observed in the OB + MS group. The oxidative damage to proteins (advanced glycation end products, AGE; advanced oxidation protein products, AOPP) and lipids (8-isoprostanes, 8-isop; 4-hydroxynoneal) was higher in OB as well as OB + MS patients. We noticed that AGE and AOPP levels diminished after the bariatric treatment, whereas redox status (ratio of GSH to oxidized glutathione) was still reduced in the OB + MS group. Summarizing, morbid obesity is associated with disturbances in the antioxidant barrier and enhanced oxidative damage to proteins and lipids. Although bariatric surgery improves redox homeostasis in obese patients, those with metabolic syndrome show a continuous decrease in the antioxidant status. In patients undergoing bariatric treatment, antioxidant supplementation may be considered.


2004 ◽  
Vol 22 (4) ◽  
pp. 213-217 ◽  
Author(s):  
Abdulkadir Yildirim ◽  
Konca Altinkaynak ◽  
Hulya Aksoy ◽  
Y. Nuri Sahin ◽  
Fatih Akcay

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