Interference-free and high precision biosensor based on surface enhanced Raman spectroscopy integrated with surface molecularly imprinted polymer technology for tumor biomarker detection in human blood

2019 ◽  
Vol 143 ◽  
pp. 111599 ◽  
Author(s):  
Xueliang Lin ◽  
Yunyi Wang ◽  
Lingna Wang ◽  
Yudong Lu ◽  
Jin Li ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Human Blood ◽  
Molecularly Imprinted Polymer ◽  
Surface Enhanced Raman Spectroscopy ◽  
Tumor Biomarker ◽  
Biomarker Detection ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

scholarly journals Photoconjugation of Molecularly Imprinted Polymer Nanoparticles for Surface-Enhanced Raman Detection of Propranolol

2015 ◽  
Vol 7 (49) ◽  
pp. 27479-27485 ◽  
Author(s):  
Tripta Kamra ◽  
Changgang Xu ◽  
Lars Montelius ◽  
Joachim Schnadt ◽  
Samurdhi A. Wijesundera ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Polymer Nanoparticles ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

A Ag-molecularly imprinted polymer composite for efficient surface-enhanced Raman scattering activities under a low-energy laser

The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 3239-3243 ◽  
Author(s):  
Shaona Chen ◽  
Xin Li ◽  
Yan Guo ◽  
Jingyao Qi
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Ag Particles ◽  
Surface Enhanced ◽  
Molecular Imprinting Technique ◽  
Surface Enhanced Raman ◽  
Energy Laser ◽  
Enhanced Raman Scattering ◽  
Low Energy Laser

In this work, we have fabricated flower-shaped Ag particles coated with a molecularly imprinted polymer (Ag@MIP) based on the molecular imprinting technique and SERS technology.

scholarly journals Sensitive and Selective Detection of New Red Colorant Based on Surface-Enhanced Raman Spectroscopy Using Molecularly Imprinted Hydrogels

2019 ◽  
Vol 9 (13) ◽  
pp. 2672 ◽  
Author(s):  
Jing Neng ◽  
Kaiyun Xu ◽  
Yan Wang ◽  
Kan Jia ◽  
Qi Zhang ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Selective Detection ◽  
Molecularly Imprinted ◽  
Au Nps ◽  
Relative Standard ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
Positively Charged

A polyacrylamide-based molecularly imprinted hydrogel (MIH) doped with positively charged gold nanoparticles (Au NPs) has been synthesized via a free radical polymerization of acrylamide (AM) aqueous solution containing positively charged Au NPs as a Raman active substrate, New Red colorant as a template molecule, N,N’-methylenebis(acrylamide) as a crosslinking agent, and potassium persulfate as an initiator. The Au NPs-doped MIHs were subsequently explored as a Raman active substrate for the sensitive and selective detection of New Red colorant via surface-enhanced Raman spectroscopy (SERS). The logarithmic intensity of the characteristic peak of New Red at 1572 cm−1 was proportional to the logarithmic concentration of New Red with a detection linear range of 1.64 × 10−6 to 1.64 × 10−4 M and a limit of detection (LOD) of 1.64 × 10−7 M. The recoveries ranged from 86.3% to 100.6% with a relative standard deviation (RSD) in the range of 2.3% to 7.7%. The RSD and recovery rates for the detection of New Red spiked in a sports drink sample were 1.8% to 7.7% and 91.0% to 97.1%, respectively. These results showed that SERS combined with MIHs as Raman active substrates could provide a sensitive, selective, and effective approach for the detection of the New Red colorant in beverage matrix.

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