Flux balance analysis of nutritional modulation assisted changes in two-stage fed-batch fermentation by Clostridium acetobutylicum

2019 ◽  
Vol 7 ◽  
pp. 100264
Author(s):  
Saumya Ahlawat ◽  
Mehak Kaushal ◽  
Basavaraj Palabhanvi ◽  
Gargi Goswami ◽  
Debasish Das
2013 ◽  
Vol 29 (2) ◽  
pp. 520-531 ◽  
Author(s):  
Hector Budman ◽  
Nilesh Patel ◽  
Melih Tamer ◽  
Walid Al-Gherwi

2011 ◽  
Vol 16 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Iliana Barrera-Martínez ◽  
R. Axayácatl González-García ◽  
Edgar Salgado-Manjarrez ◽  
Juan S. Aranda-Barradas

2013 ◽  
Vol 805-806 ◽  
pp. 163-167
Author(s):  
Hui Yan Huang ◽  
Xiao Ju Zhang ◽  
Heng Jiang Li ◽  
Jiang Lu ◽  
Shi Jie Li

Clostridium acetobutylicum parent strain was treated by ultraviolet irradiation at different minutes. The UV treated strains were cultivated in cornmeal medium with butanol added to the medium prior to cultivation. By increasing butanol content gradually in the medium, high butanol tolerance mutants were screened. Results show that mutants by UV treated for 4 minutes display best butanol tolerance and high butanol productivity. With 12g/L butanol added in the medium, the mutants still grow rapidly and accumulated 18.0g/L butanol at the end of 69 hr cultivation. Using sweet corn stalk juice as raw material, the maximum butanol produced by fermentation with the mutants reached 15.3g/L and 18.3g/L in batch and fed-batch fermentation respectively.


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