Co-gasification reactivity and kinetics of municipality and coffee waste residue hydrochar and South African density separated coal blends

2021 ◽  
pp. 100877
Author(s):  
R.C. Uwaoma ◽  
C.A. Strydom ◽  
J.R. Bunt ◽  
R.H. Matjie ◽  
G.N. Okolo ◽  
...  
Author(s):  
Zachary O. Siagi ◽  
Makame Mbarawa

One of the most important steps in the wet limestone-gypsum flue gas desulphurization (WFGD) process is CaCO3 dissolution, which provides the dissolved alkalinity necessary for SO2 absorption. Accurately evaluating the CaCO3 dissolution rate is important in the design and efficient operation of WFGD plants. In the present work, the dissolution of limestone from different sources in South Africa has been studied in a pH-stat apparatus under conditions similar to those encountered in wet FGD processes. The influence of various parameters such as the reaction temperature (30 ≤ T ≤ 70°C), CaCO3 particle size (25 ≤ dp ≤ 63μm), solution acidity (4 ≤ pH ≤ 6), and chemical composition were studied in order to determine the kinetics of CaCO3 dissolution. The results obtained indicate that the dissolution rate increased with a decrease in particle size and an increase in temperature. The dissolution curves were evaluated in order to test the shrinking core model for fluid–solid systems. The analysis indicated that the dissolution of CaCO3 was controlled by chemical reaction, i.e. 1 − (1 − X)1/3 = kt.


2015 ◽  
Vol 22 (3) ◽  
pp. 233-240 ◽  
Author(s):  
Qing Zhao ◽  
Cheng-jun Liu ◽  
Pei-yang Shi ◽  
Bo Zhang ◽  
Mao-fa Jiang ◽  
...  

2021 ◽  
Author(s):  
Son Tung Ngo ◽  
Trung Hai Nguyen ◽  
Duc-Hung Pham ◽  
Nguyen Thanh Tung ◽  
Pham Cam Nam

Understanding thermodynamics and kinetics of the binding process of antibody to SARS-CoV-2 receptor-binding domain (RBD) of Spike protein is very important for the development of COVID19 vaccines. Especially, it is essential to understand how the binding mechanism may change under the effects of RBD mutations. In this context, we have demonstrated that the South African variant (B1.351 or 501Y.V2) can resist the neutralizing antibody (NAb). Three substitutions in RBD including K417N, E484K, and N501Y alters the free energy landscape, binding pose, binding free energy, binding kinetics, and unbinding pathway of RBD + NAb complexes. The low binding affinity of NAb to 501Y.V2 RBD confirms the antibody resistance of the South African variant.


2021 ◽  
Author(s):  
Son Tung Ngo ◽  
Trung Hai Nguyen ◽  
Duc-Hung Pham ◽  
Nguyen Thanh Tung ◽  
Pham Cam Nam

Understanding thermodynamics and kinetics of the binding process of antibody to SARS-CoV-2 receptor-binding domain (RBD) of Spike protein is very important for the development of COVID19 vaccines. Especially, it is essential to understand how the binding mechanism may change under the effects of RBD mutations. In this context, we have demonstrated that the South African variant (B1.351 or 501Y.V2) can resist the neutralizing antibody (NAb). Three substitutions in RBD including K417N, E484K, and N501Y alters the free energy landscape, binding pose, binding free energy, binding kinetics, and unbinding pathway of RBD + NAb complexes. The low binding affinity of NAb to 501Y.V2 RBD confirms the antibody resistance of the South African variant.


2006 ◽  
Vol 20 (3) ◽  
pp. 1201-1210 ◽  
Author(s):  
Linxian Zhang ◽  
Jiejie Huang ◽  
Yitian Fang ◽  
Yang Wang

2021 ◽  
Author(s):  
Son Tung Ngo ◽  
Trung Hai Nguyen ◽  
Duc-Hung Pham ◽  
Nguyen Thanh Tung ◽  
Pham Cam Nam

Understanding thermodynamics and kinetics of the binding process of antibody to SARS-CoV-2 receptor-binding domain (RBD) of Spike protein is very important for the development of COVID19 vaccines. Especially, it is essential to understand how the binding mechanism may change under the effects of RBD mutations. In this context, we have demonstrated that the South African variant (B1.351 or 501Y.V2) can resist the neutralizing antibody (NAb). Three substitutions in RBD including K417N, E484K, and N501Y alters the free energy landscape, binding pose, binding free energy, binding kinetics, and unbinding pathway of RBD + NAb complexes. The low binding affinity of NAb to 501Y.V2 RBD confirms the antibody resistance of the South African variant.


2021 ◽  
Author(s):  
Son Tung Ngo ◽  
Trung Hai Nguyen ◽  
Duc-Hung Pham ◽  
Nguyen Thanh Tung ◽  
Pham Cam Nam

Understanding thermodynamics and kinetics of the binding process of antibody to SARS-CoV-2 receptor-binding domain (RBD) of Spike protein is very important for the development of COVID19 vaccines. Especially, it is essential to understand how the binding mechanism may change under the effects of RBD mutations. In this context, we have demonstrated that the South African variant (B1.351 or 501Y.V2) can resist the neutralizing antibody (NAb). Three substitutions in RBD including K417N, E484K, and N501Y alters the free energy landscape, binding pose, binding free energy, binding kinetics, and unbinding pathway of RBD + NAb complexes. The low binding affinity of NAb to 501Y.V2 RBD confirms the antibody resistance of the South African variant.


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