Risk of wound infection and safety profile of amoxicillin in healthy patients which required third molar surgery: a systematic review and meta-analysis

2015 ◽  
Vol 53 (9) ◽  
pp. 796-804 ◽  
Author(s):  
M.A. Isiordia-Espinoza ◽  
O.H. Aragon-Martinez ◽  
J.F. Martínez-Morales ◽  
J.R. Zapata-Morales
Keyword(s):  
Systematic Review ◽  
Wound Infection ◽  
Safety Profile ◽  
Meta Analysis ◽  
Third Molar ◽  
Third Molar Surgery

scholarly journals Panoramic versus CBCT used to reduce inferior alveolar nerve paresthesia after third molar extractions: a systematic review and meta-analysis

2020 ◽  
Vol 49 (4) ◽  
pp. 20190265
Author(s):  
Nathalia Calzavara Del Lhano ◽  
Rosangela Almeida Ribeiro ◽  
Carolina Castro Martins ◽  
Neuza Maria Souza Picorelli Assis ◽  
Karina Lopes Devito
Keyword(s):  
Systematic Review ◽  
Panoramic Radiography ◽  
Meta Analysis ◽  
Inferior Alveolar Nerve ◽  
Third Molar ◽  
Risk Of Bias ◽  
Third Molar Surgery ◽  
Reference List ◽  
Significant Heterogeneity ◽  
Eligibility Criteria

Objectives: The aim of this systematic review was to verify whether CBCT in comparison with panoramic radiography reduced the cases of temporary paresthesias of the inferior alveolar nerve (IAN) associated with third molar extractions. Methods: The literature search included five databases (PubMed, Scopus, Web of Science, Cochrane, SciELO), in addition to gray literature and hand search of reference list of included studies. Two reviewers independently screened titles/abstracts, and full texts according to eligibility criteria, extracted data and evaluated risk of bias through Revised Cochrane Risk of Bias Tool for Randomized Trials (RoB 2.0). Data were meta-analyzed by comparing CBCT versus panoramic radiographs for number of events (temporary paresthesia after third molar surgery). Fixed effect model was used for non-significant heterogeneity; relative risk (RR) and 95% CI were calculated. The certainty of evidence was evaluated by Grading of Recommendations, Assessment, Development, and Evaluation (GRADE). Results: Four randomized controlled trials (RCTs) were included in meta-analysis, and for the majority of domains they presented low risk of bias. RR was 1.23 (95% IC: 0.75–2.02; I2: 0%; p = 0.43) favouring panoramic radiography, but without significant effect, and with moderate certainty of evidence. Conclusions: We concluded that both interventions had a similar ability to reduce temporary paresthesia of the IAN after third molar surgery with moderate certainty of evidence.

Does the Use of Articaine Increase the Risk of Hypesthesia in Lower Third Molar Surgery? A Systematic Review and Meta-Analysis

2021 ◽  
Vol 79 (1) ◽  
pp. 64-74
Author(s):  
Emerson Filipe de Carvalho Nogueira ◽  
Fábio Andrey da Costa Araújo ◽  
Tatiane Fonseca Faro ◽  
Renata de Albuquerque Cavalcanti Almeida ◽  
Ricardo José de Holanda Vasconcellos
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Third Molar ◽  
Third Molar Surgery

scholarly journals Comparative efficacy and safety of different corticosteroids to reduce inflammatory complications after mandibular third molar surgery: a systematic review and network meta-analysis protocol

2021 ◽  
Author(s):  
Joao Vitor Canellas ◽  
◽  
Fabio Ritto ◽  
Paul Tiwana ◽  
◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Third Molar ◽  
Optimal Dose ◽  
Third Molar Surgery ◽  
Mandibular Third Molar ◽  
Review Question ◽  
Postoperative Inflammatory Complications ◽  
Mandibular Third Molar Surgery ◽  
Analysis Protocol

Review question / Objective: This systematic review aims to compare the effects of different corticosteroids to reduce postoperative inflammatory complications (pain, edema, and trismus) after mandibular third molar surgery by applying a frequentist network meta-analysis approach. To this end, the proposed study will answer the following questions: 1) Among diverse corticosteroids currently available, what is the best preoperative option to control postoperative inflammatory complications? 2) What is the optimal dose and route of administration of corticosteroids prior to mandibular third molar surgery to control the pain, edema, and trismus induced by the surgery? Condition being studied: Inflammatory complications after mandibular third molar surgery (Pain, edema, and trismus).

scholarly journals Platelet-Rich Fibrin in third molar surgery. Systematic review and meta-analysis protocol

2020 ◽  
Author(s):  
Gaston Salas ◽  
Shuheng Lai ◽  
Francisca Verdugo-Paiva ◽  
Roberto Requena
Keyword(s):  
Systematic Review ◽  
Wound Healing ◽  
Meta Analysis ◽  
Grey Literature ◽  
Third Molar ◽  
Risk Of Bias ◽  
Third Molar Surgery ◽  
Cochrane Central Register ◽  
Eligibility Criteria ◽  
Platelet Rich Fibrin

Objective: The objective of this systematic review is to assess the effectiveness and safety of platelet rich fibrin (PRF) in third molar surgery. Data sources: A comprehensive search strategy is meant to be used in an attempt to identify all relevant RCTs, ongoing investigation reported in specialty congresses and trials regardless of language or publication status (published, unpublished, in press, and in progress). Search will be conducted in The Cochrane Central Register of Controlled Trials (CENTRAL); PUBMED; Embase; Lilacs, and also conduct a search through trial registries of the International Clinical Trials Registry Platform (ICTRP), Word Health Organization (WHO) and the ClinicalTrials.gov, US National Institutes of Health (NIH), grey literature search and specialty congress will be reviewed. Eligibility criteria: We will include randomised trials evaluating the effect of PRF on wound healing after third molar surgery. Two reviewers will independently screen each study for eligibility, extract data, and assess the risk of bias using Cochrane 'risk of bias' tool. We will pool the results using meta-analysis and will apply the GRADE system to assess the certainty of the evidence for each outcome. Ethics and dissemination: As researchers will not access information that could lead to the identification of an individual participant, obtaining ethical approval was waived. Keywords: platelet-rich fibrin; third molars; wound healing; systematic review

scholarly journals Comparison of Submucosal With Intramuscular or Intravenous Administration of Dexamethasone for Third Molar Surgeries: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Chengyu Hou ◽  
Feng Liu ◽  
Chengbin Liu
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Third Molar ◽  
Pooled Analysis ◽  
Third Molar Surgery ◽  
Quality Of Evidence ◽  
Pain Scores ◽  
Significant Difference ◽  
Mandibular Third Molar Surgery

Objective: The study aimed to review evidence on the efficacy of submucosal (SM) administration vs. intravenous (IV) or intramuscular (IM) route of injections of dexamethasone for improving outcomes after mandibular third molar surgery.Methods: PubMed, Embase, CENTRAL, and Google Scholar were searched for randomized controlled trials (RCTs) up to 20th May 2021. Early (2–3 days) and late (7 days) outcomes were compared between SM vs. IV or IM dexamethasone. Quality of evidence was assessed based on GRADE.Results: Thirteen trials were included in the systematic review and 10 in the meta-analysis. Meta-analysis indicated a significant reduction in early pain with IV dexamethasone but no such difference for late pain compared to the SM group. There was no difference in early and late swelling scores between the SM and IV groups. Pooled analysis indicated no significant difference in early and late trismus between SM and IV groups. Comparing SM with IM dexamethasone, there was no significant difference in early and late pain scores. Swelling in the early and late postoperative periods was not significantly different between the two groups. There was no significant difference in early and late trismus between SM and IM groups. The quality of evidence was low for all outcomes.Conclusion: Low-quality evidence suggests that SM infiltration of dexamethasone results in similar outcomes as compared to IV or IM administration of the drug after third molar surgeries. Further high-quality RCTs are needed to corroborate the current conclusions.

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