scholarly journals Extracellular Matrix Elasticity Determines Stem Cell Fate through Stretch-Activated Ion Channels

2014 ◽  
Vol 106 (2) ◽  
pp. 572a
Author(s):  
Medha M. Pathak ◽  
Jamison L. Nourse ◽  
Truc Tran ◽  
Janahan Arulmoli ◽  
Lisa A. Flanagan ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Ion Channels ◽  
Cell Fate ◽  
Stem Cell Fate ◽  
Matrix Elasticity ◽  
Stretch Activated Ion Channels

scholarly journals The role of extracellular matrix on liver stem cell fate: A dynamic relationship in health and disease

2019 ◽  
Vol 106 ◽  
pp. 49-56 ◽  
Author(s):  
Natalia Sánchez-Romero ◽  
Pilar Sainz-Arnal ◽  
Iris Pla-Palacín ◽  
Pablo Royo Dachary ◽  
Helen Almeida ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Cell Fate ◽  
Stem Cell Fate ◽  
Dynamic Relationship ◽  
Health And Disease

Directing Stem Cell Fate in 3D Through Cell Inert and Adhesive Diblock Copolymer Domains

2013 ◽  
Author(s):  
Somyot Chirasatitsin ◽  
Priyalakshmi Viswanathan ◽  
Giuseppe Battaglia ◽  
Adam J. Engler
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Cell Adhesion ◽  
Cell Fate ◽  
Diblock Copolymer ◽  
Stem Cell Differentiation ◽  
Stem Cell Fate ◽  
Cell Behaviors ◽  
Cell Structures

Adhesions are important cell structures required to transduce a variety of chemical and mechanics signals from outside-in and vice versa, all of which regulate cell behaviors, including stem cell differentiation (1). Though most biomaterials are coated with an adhesive ligand to promote adhesion, they do not often have a uniform distribution that does not match the heterogeneously adhesive extracellular matrix (ECM) in vivo (2). We have previously shown that diblock copolymer (DBC) mixtures undergo interface-confined de-mixing to form nanodomins of one copolymer in another (3). Here we demonstrate how diblock copolymer mixtures can be made into foams with nanodomains to better recapitulate native ECM adhesion regions and influence cell adhesion.

scholarly journals Immobilization after injury alters extracellular matrix and stem cell fate

2020 ◽  
Vol 130 (10) ◽  
pp. 5444-5460 ◽  
Author(s):  
Amanda K. Huber ◽  
Nicole Patel ◽  
Chase A. Pagani ◽  
Simone Marini ◽  
Karthik R. Padmanabhan ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Cell Fate ◽  
Stem Cell Fate

Extracellular Matrix Regulation of Stem Cell Fate

2018 ◽  
Vol 4 (1) ◽  
pp. 13-21 ◽  
Author(s):  
Quinton Smith ◽  
Sharon Gerecht
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Cell Fate ◽  
Stem Cell Fate

scholarly journals Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate

2018 ◽  
Vol 19 (4) ◽  
pp. 1003 ◽  
Author(s):  
Elina Chermnykh ◽  
Ekaterina Kalabusheva ◽  
Ekaterina Vorotelyak
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Cell Fate ◽  
Epidermal Stem Cell ◽  
Stem Cell Fate
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