Cyclin D1 (CCND1) G870A gene polymorphism is an ethnicity-dependent risk factor for digestive tract cancers: A meta-analysis comprising 20,271 subjects

2012 ◽  
Vol 36 (2) ◽  
pp. 106-115 ◽  
Author(s):  
Bo Chen ◽  
Lei Cao ◽  
Ping Yang ◽  
Yong Zhou ◽  
Xiao-Ting Wu
Keyword(s):  
Risk Factor ◽  
Gene Polymorphism ◽  
Cyclin D1 ◽  
Digestive Tract ◽  
Meta Analysis ◽  
Ccnd1 G870a

scholarly journals The CCND1 G870A Gene Polymorphism and Brain Tumor Risk: a Meta-analysis

2014 ◽  
Vol 15 (8) ◽  
pp. 3607-3612 ◽  
Author(s):  
Ling-Yan Qin ◽  
Li-Gang Zhao ◽  
Xu Chen ◽  
Ping Li ◽  
Zheng Yang ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Gene Polymorphism ◽  
Meta Analysis ◽  
Tumor Risk ◽  
Ccnd1 G870a

scholarly journals Cyclin D1 G870A Polymorphism and Risk of Nasopharyngeal Carcinoma: A Meta-Analysis

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Meng Li ◽  
Weijian Dai ◽  
Huanqin Zhou
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Cyclin D1 ◽  
Protective Factor ◽  
Population Analysis ◽  
Meta Analysis ◽  
Polymorphic Variants ◽  
Positive Results ◽  
Carcinoma Risk ◽  
Ccnd1 G870a ◽  
Ccnd1 G870a Polymorphism

Recently, there have been a number of studies on the association between cyclin D1 G870A polymorphism and nasopharyngeal carcinoma risk. However, the results of previous reports remain controversial and ambiguous. Thus, we performed a meta-analysis to explore more precisely the association between cyclin D1 G870A polymorphism and the risk of nasopharyngeal carcinoma. No significant association was found between cyclin D1 G870A polymorphism and nasopharyngeal carcinoma risk in total population analysis. In the subgroup meta-analysis by ethnicity, a negative association was shown in Caucasian subgroup, and no significant association in any genetic models among Asians was observed. In summary, positive results have been shown on the search for polymorphic variants influencing the risk of NPC. This meta-analysis provides evidence of the association between CCND1 G870A polymorphism and NPC risk, supporting the hypothesis that CCND1 870A allele probably acts as an important NPC protective factor in Caucasians but not in Asians. Since the results of our meta-analysis are preliminary and may be biased by the relatively small number of subjects, they still need to be validated by well-designed studies using larger samples in the future.

The cyclin D1 (CCND1) G870A polymorphism and lung cancer susceptibility: a meta-analysis

Tumor Biology ◽  
2013 ◽  
Vol 34 (6) ◽  
pp. 3831-3837 ◽  
Author(s):  
Changxi Zhou ◽  
Huaijie An ◽  
Mingdong Hu ◽  
Qinghui Liu ◽  
Peiliang Geng ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cyclin D1 ◽  
Cancer Susceptibility ◽  
Meta Analysis ◽  
Ccnd1 G870a ◽  
Ccnd1 G870a Polymorphism ◽  
Lung Cancer Susceptibility

scholarly journals NAD(P)H: Quinone Oxidoreductase 1 (NQO1) C609T Gene Polymorphism Association with Digestive Tract Cancer: A Meta-analysis

2013 ◽  
Vol 14 (4) ◽  
pp. 2349-2354 ◽  
Author(s):  
Cheng-Lin Zhu ◽  
Qiang Huang ◽  
Chen-Hai Liu ◽  
Xian-Sheng Lin ◽  
Fang Xie ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Digestive Tract ◽  
Meta Analysis ◽  
Quinone Oxidoreductase ◽  
Digestive Tract Cancer ◽  
Tract Cancer

scholarly journals Association between cyclin D1 (CCND1) G870A polymorphism and gastric cancer risk: a meta-analysis

Oncotarget ◽  
2016 ◽  
Vol 7 (40) ◽  
pp. 66109-66118 ◽  
Author(s):  
Yafei Zhang ◽  
Xianling Zeng ◽  
Hongwei Lu ◽  
Hong Ji ◽  
Enfa Zhao ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Risk ◽  
Cyclin D1 ◽  
Meta Analysis ◽  
Gastric Cancer Risk ◽  
Ccnd1 G870a ◽  
Ccnd1 G870a Polymorphism

scholarly journals Cyclin D1 G870A gene polymorphism and risk of leukemia and hepatocellular carcinoma: a meta-analysis

2015 ◽  
Vol 14 (2) ◽  
pp. 5171-5180 ◽  
Author(s):  
Y. Zhao ◽  
H.R. He ◽  
M.Y. Wang ◽  
X.D. Ren ◽  
L. Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gene Polymorphism ◽  
Cyclin D1 ◽  
Meta Analysis
Sign in / Sign up

Export Citation Format

Share Document