Collagen and nano-hydroxyapatite interactions in alginate-based microcapsule provide an appropriate osteogenic microenvironment for modular bone tissue formation

2021 ◽  
pp. 118807
Author(s):  
Ayla Hassani ◽  
Ali Baradar Khoshfetrat ◽  
Reza Rahbarghazi ◽  
Shinji Sakai
Keyword(s):  
Bone Tissue ◽  
Tissue Formation ◽  
Bone Tissue Formation

Nanomaterial-based scaffolds for bone tissue engineering and regeneration

Nanomedicine ◽  
2020 ◽  
Vol 15 (20) ◽  
pp. 1995-2017
Author(s):  
Guo Ye ◽  
Fangyuan Bao ◽  
Xianzhu Zhang ◽  
Zhe Song ◽  
Youguo Liao ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Bone Tissue Regeneration ◽  
Tissue Formation ◽  
Topological Features ◽  
Potential Risks ◽  
Underlying Mechanisms ◽  
Nanocomposite Scaffolds ◽  
Bone Tissue Formation

The global incidence of bone tissue injuries has been increasing rapidly in recent years, making it imperative to develop suitable bone grafts for facilitating bone tissue regeneration. It has been demonstrated that nanomaterials/nanocomposites scaffolds can more effectively promote new bone tissue formation compared with micromaterials. This may be attributed to their nanoscaled structural and topological features that better mimic the physiological characteristics of natural bone tissue. In this review, we examined the current applications of various nanomaterial/nanocomposite scaffolds and different topological structures for bone tissue engineering, as well as the underlying mechanisms of regeneration. The potential risks and toxicity of nanomaterials will also be critically discussed. Finally, some considerations for the clinical applications of nanomaterials/nanocomposites scaffolds for bone tissue engineering are mentioned.

Bioactive and Biocompatible Silica/Pseudowollastonite Aerogels

2014 ◽  
Vol 96 ◽  
pp. 21-26 ◽  
Author(s):  
P.J. Reséndiz-Hernández ◽  
D.A. Cortés-Hernández ◽  
Juan Méndez Nonell ◽  
J.C. Escobedo-Bocardo
Keyword(s):  
Bone Tissue ◽  
Ambient Pressure ◽  
Sol Gel ◽  
Ambient Pressure Drying ◽  
Bone Tissue Regeneration ◽  
Tissue Formation ◽  
Potential Applications ◽  
Ft Ir ◽  
Bone Tissue Formation

Silica aerogels have attracted increasingly more attention due to their extraordinary properties and their existing and potential applications in a wide variety of technological areas. Materials that promote bone-tissue formation at their surface and bond to osseous tissues when implanted are called bioactive, such as pseudowollastonite particles. In this work, the synthesis of aerogels with pseudowollastonite particles was performed. The synthesis involved the preparation of an alcogel by a two step sol-gel route followed by ambient pressure drying. To promote a higher bioactivity the obtained aerogels were then biomimetically treated using simulated body fluids, SBF and 1.5 SBF. A high bioactivity was demonstrated by FT-IR, SEM, EDS, and XRD. The in vitro biocompatibility was assessed by testing cytotoxicity using rat osteoblasts cultures. The results obtained indicate that these materials are highly potential aerogels for bone tissue regeneration.

scholarly journals Influence of Implants Surface Properties on Bone Tissue Formation in the Ectopic Osteogenesis Test

2017 ◽  
Vol 162 (6) ◽  
pp. 812-814 ◽  
Author(s):  
S. V. Nadezhdin ◽  
E. V. Zubareva ◽  
Yu. E. Burda ◽  
Yu. R. Kolobov ◽  
M. B. Ivanov ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Surface Properties ◽  
Tissue Formation ◽  
Ectopic Osteogenesis ◽  
Bone Tissue Formation

Bone tissue formation around two titanium implant surfaces placed in bone defects filled with bone substitute material or blood clot: A pilot study

2019 ◽  
Vol 21 (6) ◽  
pp. 1175-1180
Author(s):  
Guilherme dos Santos Trento ◽  
Rubens Spin‐Neto ◽  
Ana Paula Farnezi Bassi ◽  
Roberta Okamoto ◽  
Marisa Aparecida Cabrini Gabrielli ◽  
...  
Keyword(s):  
Pilot Study ◽  
Bone Tissue ◽  
Bone Substitute ◽  
Blood Clot ◽  
Titanium Implant ◽  
Bone Defects ◽  
Tissue Formation ◽  
Bone Substitute Material ◽  
Substitute Material ◽  
Bone Tissue Formation

In Situ Controlled Release of rhBMP-2 in Gelatin-Coated 3D Porous Poly(ε-caprolactone) Scaffolds for Homogeneous Bone Tissue Formation

2013 ◽  
Vol 15 (1) ◽  
pp. 84-94 ◽  
Author(s):  
Qingchun Zhang ◽  
Ke Tan ◽  
Yan Zhang ◽  
Zhaoyang Ye ◽  
Wen-Song Tan ◽  
...  
Keyword(s):  
Controlled Release ◽  
Bone Tissue ◽  
Tissue Formation ◽  
Bone Tissue Formation ◽  
Porous Poly
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