Detection of Pre-ejection Septal Flash and Systolic Shuffle by Curved Color M-mode can Predict Favorable Outcome After Cardiac Resynchronization Therapy

2009 ◽  
Vol 15 (7) ◽  
pp. S138
Author(s):  
Kazuya Murata ◽  
Chikage Kihara ◽  
Takeo Tanaka ◽  
Yasuaki Wada ◽  
Masunori Matsuzaki
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Favorable Outcome ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Septal Flash

Gauging the response to cardiac resynchronization therapy: The important interplay between predictor variables and definition of a favorable outcome

2017 ◽  
Vol 34 (3) ◽  
pp. 371-375 ◽  
Author(s):  
Milan Petrovic ◽  
Marija Petrovic ◽  
Goran Milasinovic ◽  
Bosiljka Vujisic Tesic ◽  
Danijela Trifunovic ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Favorable Outcome ◽  
Predictor Variables ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Definition Of

P539Comparative analysis of patients with cardiac resynchronization therapy depending on septal flash

EP Europace ◽  
2020 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
N Shirokov ◽  
V Kuznetsov ◽  
A Soldatova ◽  
L Malishevskii ◽  
D Krinochkin
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Interventricular Septum ◽  
Functional Class ◽  
Doppler Imaging ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Basal Segment ◽  
Group I ◽  
Functional Features ◽  
Septal Flash

Abstract Background Mechanical dyssynchrony (MD) and superresponse (SR) to cardiac resynchronisation therapy (CRT) relationship is still debated. Aim To assess clinical and morpho-functional features of the heart in patients with congestive heart failure (CHF) after cardiac resynchronization therapy (CRT) depending on septal flash (SF). Materials and methods The study enrolled 60 patients (92.0% men, 8.0% women; mean age 54.5 ± 10.4 years; 70.0% had left bundle branch block (LBBB) with II-IV NYHA functional class CHF. SF (mechanical anomaly of interventricular septum (IVS) movement) is determined according to speckle tracking echocardiography (STE) and tissue Doppler imaging (TDI). Patients were divided into two groups: with SF (I group, n = 10) and without SF (II group, n = 50). Results At baseline the groups did not differ in main clinical characteristics including QRS width and LBBB. Mechanical interventricular delay was higher in group I (65.5 ms [53.5;95.5] vs 31.0 ms [15.0;64.5]; р=0.026). Basal segment of IVS longitudinal strain (LS) delay by STE (257.5 ms [156.3;293.8] vs 323.5 ms [262.5;377.8]; р=0.024) and LS delay by TDI (204.0 ms [170.8;260.3] vs 434.0 ms [370.0;489.0]; р<0.001) were significantly lower in group with SF. According to logistic regression a combination of LS apical segment of IVS by STE (HR 0.607; 95% Cl 0.369 – 0.989; р=0,048) and LS delay basal segment of IVS by TDI (HR 0.969; 95% Cl 0.0945 – 0.993; р=0.011) had a relationship with SF. According to ROC analysis sensitivity and specificity of this model in SF definition in patients with CRT were 87.5% and 86.5% (AUC = 0.939; p < 0.01). Mean changes in LV ESV (52.0 ml [32.5;72.8] vs 19,0 ml [1.3;40.0]; р=0.002) and LV ejection fraction (EF) (13.0% [5.5;18.8] vs 4.0% [2.0;9.0]; р=0.002) were significantly higher in patients with SF. All patients in group I had a super-response to CRT (ESV LV decrease ≥30%); 42.0% patients in group II were superresponders (р<0.001). Conclusion SF could be determined by STE and TDI. SF is associated with severe mechanical interventricular dyssynchrony and superresponse to CRT. Patients with SF have significantly better LV EF dynamics after CRT. Abstract Figure. Septal Flash in patient with SR to CRT

scholarly journals Relationship of septal flash with electromechanical dyssynchrony and super-response to cardiac resynchronization therapy

2020 ◽  
Vol 5 (2) ◽  
pp. 93-98
Author(s):  
Nikita E. Shirokov ◽  
Vadim A. Kuznetsov ◽  
Lev M. Malishevskii ◽  
Viktor V. Todosiichuk ◽  
Anna M. Soldatova ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Interventricular Septum ◽  
Left Ventricular ◽  
Functional Class ◽  
Doppler Imaging ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Group I ◽  
Relationship Of ◽  
Septal Flash

Objectives - to identify a relationship of septal flash (SF) with a super-response to cardiac resynchronization therapy (CRT), apical rocking (AR) and signs of left bundle brunch block (LBBB) in patients with congestive heart failure (CHF). Material and methods. The study included 38 patients (92.1% men; mean age 54.3±9.4 years) with II-IV NYHA functional class CHF. Left bundle brunch block (LBBB) was diagnosed according to 3 criteria: American Heart Association (AHA) 2009, European Society of Cardiology (ESC) 2013, Strauss. Septal flash (SF, mechanical anomaly of interventricular septum (IVS) movement) is determined according to speckle tracking echocardiography (STE) and tissue Doppler imaging (TDI). The patients were divided into two groups: with SF (I group, n=8) and without SF (II group, n=30). Mean follow-up was 34.5 [13.8;55.3]. Results. At baseline the groups did not differ in main clinical characteristics including QRS. The left ventricular (LV) ejection fraction (EF) was higher in group I (33.1%±1.7 and 30.0%±4.0; p=0.044). Basal segment of IVS longitudinal strain (LS) delay by STE (258.0 [144.0;294.0] ms vs 323.5 [273.3;385.0] ms; р=0.024) and LS delay by TDI (176.0 [146.8;287.3] ms vs 415.5 [315.8;493.5] ms; р30%); 53.1% of patients in group II were super responders (р

scholarly journals Comparative analysis of patients with cardiac resynchronization therapy depending on septal flash presence

2019 ◽  
pp. 44-53 ◽  
Author(s):  
N. E. Shirokov ◽  
V. A. Kuznetsov ◽  
A. M. Soldatova ◽  
D. V. Krinochkin ◽  
L. M. Malishevskii
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Interventricular Septum ◽  
Functional Class ◽  
Doppler Imaging ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Basal Segment ◽  
Group I ◽  
Functional Features ◽  
Septal Flash

Aim. To assess clinical and morpho-functional features of the heart in patients with congestive heart failure (CHF) after cardiac resynchronization therapy (CRT) depending on septal flash (SF).Materials and methods. The study enrolled 60 patients (92.0% men, 8.0% women; mean age 54.5 ± 10.4 years; 70.0% had left bundle branch block (LBBB) with II-IV NYHA functional class CHF. SF (mechanical anomaly of interventricular septum (IVS) movement) is determined according to speckle tracking echocardiography (STE) and tissue Doppler imaging (TDI). Patients were divided into two groups: with SF (I group, n = 10) and without SF (II group, n = 50).Results. At baseline the groups did not differ in main clinical characteristics including QRS width and LBBB. Mechanical interventricular delay was higher in group I (65.5 ms [53.5; 95.5] vs 31.0 ms [15.0; 64.5]; р = 0.026). Basal segment of IVS longitudinal strain (LS) delay by STE (257.5 ms [156.3; 293.8] vs 323.5 ms [262.5; 377.8]; р = 0.024) and LS delay by TDI (204.0 ms [170.8; 260.3] vs 434.0 ms [370.0; 489.0]; р < 0.001) were significantly lower in group with SF. According to logistic regression a combination of LS apical segment of IVS by STE (HR 0.607; 95% Cl 0.369–0.989; р = 0.048) and LS delay basal segment of IVS by TDI (HR 0.969; 95% Cl 0.0945–0.993; р = 0.011) had a relationship with SF. According to ROC analysis sensitivity and specificity of this model in SF definition in patients with CRT were 87.5% and 86.5% (AUC = 0.939; p < 0.01). Mean changes in LV ESV (52.0 ml [32.5; 72.8] vs 19,0 ml [1.3; 40.0]; р = 0.002) and LV ejection fraction (EF) (13.0% [5.5; 18.8] vs 4.0% [2.0; 9.0]; р = 0.002) were significantly higher in patients with SF. All patients in group I had a superresponse to CRT (ESV LV decrease ≥30%); 42.0% patients in group II were superresponders (р < 0.001).Conclusion. SF could be determined by STE and TDI. SF is associated with severe mechanical interventricular dyssynchrony and superresponse to CRT. Patients with SF have significantly better LV EF dynamics after CRT. 

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