A pilot study of the metabolomic profiles of saliva from female orthodontic patients with external apical root resorption

2012 ◽

Vol 06 (04) ◽

pp. 445-453 ◽

Cited By ~ 27

Author(s):

Ahu Topkara ◽

Ali I Karaman ◽

Chung H Kau

Keyword(s):

Root Resorption ◽

Cone Beam ◽

Apical Root Resorption ◽

Long Term Follow Up ◽

Orthodontic Patients ◽

External Apical Root Resorption ◽

Long Term Observation ◽

Orthodontic Forces

ABSTRACTExternal apical root resorption (ARR) is a common iatrogenic consequence of orthodontic treatment. One of the aims of this article is to present a brief overview of the literature, including; diagnosis and etiology, with emphasis on orthodontic forces to facilitate an understand of the prevention or management of ARR in orthodontic patients. We also present a long-term follow-up observation of severe ARR, including the last obtained cone beam computed tomography (CBCT) records, to demonstrate the effect of orthodontic forces on ARR. (Eur J Dent 2012;6:445-453)

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External apical root resorption in orthodontic patients: molecular and genetic basis

Journal of Family Medicine and Primary Care ◽

10.4103/jfmpc.jfmpc_802_20 ◽

2020 ◽

Vol 9 (8) ◽

pp. 3872

Author(s):

Shilpa Kalra ◽

Prateek Gupta ◽

Tulika Tripathi ◽

Priyank Rai

Keyword(s):

Genetic Basis ◽

Root Resorption ◽

Apical Root Resorption ◽

Orthodontic Patients ◽

External Apical Root Resorption

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Genetic Predisposition to External Apical Root Resorption in Orthodontic Patients: Linkage of Chromosome-18 Marker

Journal of Dental Research ◽

10.1177/154405910308200506 ◽

2003 ◽

Vol 82 (5) ◽

pp. 356-360 ◽

Cited By ~ 96

Author(s):

R.A. Al-Qawasmi ◽

J.K. Hartsfield ◽

E.T. Everett ◽

L. Flury ◽

L. Liu ◽

...

Keyword(s):

Orthodontic Treatment ◽

Root Resorption ◽

Buccal Swab ◽

Candidate Gene Approach ◽

Linked Gene ◽

Maxillary Central Incisor ◽

Apical Root Resorption ◽

Tnf Α ◽

Orthodontic Patients ◽

External Apical Root Resorption

External apical root resorption (EARR) is a common orthodontic treatment sequela. Previous studies implicate a substantial genetic component for EARR. Using a candidate gene approach, we investigated possible linkage of EARR associated with orthodontic treatment with the TNSALP, TNF α , and TNFRSF11A gene loci. The sample was comprised of 38 American Caucasian families with a total of 79 siblings who completed comprehensive orthodontic treatment. EARR was assessed by means of pre- and post-treatment radiographs. Buccal swab cells were collected for extraction and analysis of DNA. No evidence of linkage was found with EARR and the TNF α and TNSALP genes. Non-parametric sibling pair linkage analysis identified evidence of linkage (LOD = 2.5; p = 0.02) of EARR affecting the maxillary central incisor with the microsatellite marker D18S64 (tightly linked to TNFRSF11A). This indicates that the TNFRSF11A locus, or another tightly linked gene, is associated with EARR.

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Analysis of correlation between initial alveolar bone density and apical root resorption after 12 months of orthodontic treatment without extraction

Dental Press Journal of Orthodontics ◽

10.1590/2176-9451.19.5.097-102.oar ◽

2014 ◽

Vol 19 (5) ◽

pp. 97-102 ◽

Cited By ~ 2

Author(s):

Paula Cabrini Scheibel ◽

Adilson Luiz Ramos ◽

Lilian Cristina Vessoni Iwaki ◽

Kelly Regina Micheletti

Keyword(s):

Bone Density ◽

Orthodontic Treatment ◽

Alveolar Bone ◽

Root Resorption ◽

Extraction Methods ◽

Orthodontic Movement ◽

Apical Root Resorption ◽

Orthodontic Patients ◽

External Apical Root Resorption ◽

Periapical Radiography

OBJECTIVE: The aim of the present study was to investigate the correlation between initial alveolar bone density of upper central incisors (ABD-UI) and external apical root resorption (EARR) after 12 months of orthodontic movement in cases without extraction. METHODS: A total of 47 orthodontic patients 11 years old or older were submitted to periapical radiography of upper incisors prior to treatment (T1) and after 12 months of treatment (T2). ABD-UI and EARR were measured by means of densitometry. RESULTS: No statistically significant correlation was found between initial ABD-UI and EARR at T2 (r = 0.149; p = 0.157). CONCLUSION: Based on the present findings, alveolar density assessed through periapical radiography is not predictive of root resorption after 12 months of orthodontic treatment in cases without extraction.

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