scholarly journals The role of high serum uric acid levels in androgenic and non-androgenic polycystic ovarian syndrome patients

2021 ◽  
pp. 100910
Author(s):  
Ranakishor Pelluri ◽  
Kongara Srikanth ◽  
Harika Paritala ◽  
Vamsi Ravi ◽  
Sri Pandu Mukharjee Kamma ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Polycystic Ovarian Syndrome ◽  
High Serum ◽  
Ovarian Syndrome

Attenuating the mortality risk of high serum uric acid: the role of physical activity underused

2014 ◽  
Vol 74 (11) ◽  
pp. 2034-2042 ◽  
Author(s):  
Jiunn-Horng Chen ◽  
Chi Pang Wen ◽  
Shiuan Bei Wu ◽  
Joung-Liang Lan ◽  
Min Kuang Tsai ◽  
...  
Keyword(s):  
Physical Activity ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Mortality Risk ◽  
High Serum

scholarly journals Serum uric acid and total bilirubin as putative biomarkers of resistance in Prodromal Parkinson’s disease: Longitudinal data from the PPMI study

2021 ◽  
Author(s):  
Christos Koros ◽  
Athina-Maria Simitsi ◽  
Anastasia Bougea ◽  
Nikolaos Papagiannakis ◽  
Andreas Prentakis ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Total Bilirubin ◽  
De Novo ◽  
Serum Uric Acid Level ◽  
Measurement Data ◽  
Rem Sleep Behavior Disorder ◽  
High Serum ◽  
Serum Total Bilirubin

AbstractBackgroundThe role of blood uric acid and more recently bilirubin as biomarkers in symptomatic motor PD has been increasingly established in the literature.ObjectiveOur present study assessed the role of serum uric acid and total bilirubin as putative biomarkers in a prodromal PD cohort followed longitudinally.MethodsLongitudinal 5-year serum uric acid and total bilirubin measurement data of 65 Prodromal PD patients (including REM Sleep Behavior disorder (RBD), N=39 and Hyposmia, N=26) with an abnormal DATSCAN imaging were downloaded from the Parkinson’s Progression Markers Initiative (PPMI) database. This cohort was compared with 423 de novo sporadic PD patients and 196 healthy controls enrolled in the same study.ResultsAfter adjusting for age, sex and Body Mass Index (BMI), baseline and 5-year longitudinal serum uric acid levels were higher in the Prodromal cohort and RBD subgroup as compared to the motor PD cohort. This was also true for longitudinal measurements in the Hyposmic subgroup. In contrast, baseline and longitudinal serum total bilirubin did not differ between each prodromal group and the PD cohort.ConclusionsOur results are indicative of a role of serum uric acid (but probably not of total bilirubin) as a marker of neuroprotection, in a certain subgroup of premotor patients exhibiting exclusively non motor features (hyposmia or RBD). It is possible that an inherent antioxidant resistance of a subset of RBD or hyposmia patients with high serum uric acid level delayed or precluded the emergence of a motor PD phenotype as opposed to the PD cohort.

Management of Gouty Arthritis with special reference to Vatarakta - A Case Report

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
V. Balendu Krishnan ◽  
Prashanth A. S.
Keyword(s):  
Uric Acid ◽  
Case Report ◽  
Serum Uric Acid ◽  
Serum Uric Acid Level ◽  
Gouty Arthritis ◽  
Treatment Protocol ◽  
Joint Inflammation ◽  
High Serum ◽  
Common Disease ◽  
Disease Condition

Gouty Arthritis has now become a common disease condition which we deal in Ayurveda, but a proper treatment protocol is not followed in many cases. The case reported here was as a result of improper diet and lack of exercise which resulted in an increase serum uric acid level and joint inflammation. The treatment was given at IPD level diagnosing it as Gambhira Vatarakta with valid Chikitsa Siddhanta. This case report provides us a guidelines that even a chronic gouty arthritis with a very high serum uric acid can be treated as per Vataraktha Chikitsa Siddhanta in Ayurveda.

High serum uric acid and low-grade inflammation are associated with smaller LDL and HDL particles

2009 ◽  
Vol 203 (1) ◽  
pp. 236-242 ◽  
Author(s):  
Jelena Vekic ◽  
Zorana Jelic-Ivanovic ◽  
Vesna Spasojevic-Kalimanovska ◽  
Lidija Memon ◽  
Aleksandra Zeljkovic ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
High Serum ◽  
Low Grade ◽  
Low Grade Inflammation

High serum uric acid concentration predicts poor survival in patients with breast cancer

2017 ◽  
Vol 473 ◽  
pp. 160-165 ◽  
Author(s):  
Cai-Feng Yue ◽  
Pin-Ning Feng ◽  
Zhen-Rong Yao ◽  
Xue-Gao Yu ◽  
Wen-bin Lin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Acid Concentration ◽  
High Serum ◽  
Uric Acid Concentration ◽  
Poor Survival ◽  
Serum Uric Acid Concentration

scholarly journals Serum uric acid and disorders of glucose metabolism: the role of glycosuria

2014 ◽  
Vol 47 (10) ◽  
pp. 917-923 ◽  
Author(s):  
J.A.M. Andrade ◽  
H.C. Kang ◽  
S. Greffin ◽  
M.L. Garcia Rosa ◽  
J.R. Lugon
Keyword(s):  
Uric Acid ◽  
Glucose Metabolism ◽  
Serum Uric Acid

scholarly journals The controversial role of serum uric acid in essential hypertension: relationships with indices of target organ damage

2005 ◽  
Vol 19 (3) ◽  
pp. 211-217 ◽  
Author(s):  
C Tsioufis ◽  
D Chatzis ◽  
E Vezali ◽  
K Dimitriadis ◽  
D Antoniadis ◽  
...  
Keyword(s):  
Uric Acid ◽  
Essential Hypertension ◽  
Serum Uric Acid ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ

scholarly journals Role of insulin sensitising agents in altering PSA level in PCOS

2017 ◽  
Vol 6 (11) ◽  
pp. 4986 ◽  
Author(s):  
Rajashree Panigrahy ◽  
Bratati Singh ◽  
Tapan K. Pattnaik ◽  
Sanjukta Misra
Keyword(s):  
Insulin Resistance ◽  
Polycystic Ovarian Syndrome ◽  
Specific Antigen ◽  
Serum Testosterone ◽  
Healthy Controls ◽  
Androgen Excess ◽  
Control Serum ◽  
Ovarian Syndrome ◽  
Significant Concentration

Background: Ovarian androgen production can be promoted by insulin resistance which leads to reproductive abnormalities in Polycystic Ovarian Syndrome (PCOS). A wide variety of female tissues can synthesize and secrete Prostate Specific Antigen (PSA). Androgens may take part a significant role in PSA secretion in PCOS. As insulin resistance stimulates androgen production, the baseline value of PSA may decline by insulin sensitising agents in PCOS. Present study is an attempt to measure the function of PSA as a marker of androgen excess in PCOS and to assess the role of insulin sensitising agent metformin in altering PSA level in PCOS.Methods: The study was undertaken to assess the insulin resistance, testosterone and PSA level in 45 women diagnosed as PCOS and 45 healthy controls. Alteration of insulin resistance, serum testosterone and PSA levels by metformin was also analysed.Results: A significant increase in testosterone, PSA level and insulin resistance was observed in PCOS cases when compared with control (p<0.001). When metformin was given for 4 months, improvement in insulin resistance and testosterone level was found in cases, but PSA values observed no change. Correlation was not found linking insulin resistance with PSA level prior to and after therapy.Conclusions: Serum PSA level could be detected in high significant concentration in PCOS women. Various researches explain that insulin resistance and BMI may perhaps control serum PSA level, but our result demonstrate no effect of insulin sensitising agent on serum PSA value.

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