Kinetic study for esterification of lactic acid with ethanol and hydrolysis of ethyl lactate using an ion-exchange resin catalyst

A clean process has been developed for the synthesis of 2-adamantylphenol derivatives through adamantylation of substituted phenols with adamantanols catalyzed by commercially available and recyclable ion-exchange sulfonic acid resin in acetic acid. The sole byproduct of the adamantylation reaction, namely water, could be converted into the solvent acetic acid by addition of a slight excess of acetic anhydride during the work-up procedure, making the process waste-free except for regeneration of the ion-exchange resin, and facilitating the recycling of the resin catalyst. The ion-exchange sulfonic acid resin catalyst could be readily recycled by filtration and directly reused at least ten times without a significant loss of activity. The key intermediate of adapalene, 2-(1-adamantyl)-4-bromophenol, could be produced by means of this waste-free process.

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Effectiveness of Adjustable-Volume Packed-Bed Reactor with an Ion-Exchange Resin Catalyst for Continuous Production

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN ◽

10.1252/jcej.15we243 ◽

2016 ◽

Vol 49 (7) ◽

pp. 668-672 ◽

Cited By ~ 5

Author(s):

Kota Yamazaki ◽

Naomi Shibasaki-Kitakawa ◽

Kazunori Nakashima ◽

Toshikuni Yonemoto

Keyword(s):

Ion Exchange ◽

Exchange Resin ◽

Continuous Production ◽

Packed Bed ◽

Ion Exchange Resin ◽

Packed Bed Reactor ◽

Resin Catalyst

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A trifunctional ion-exchange resin catalyst for acetylene hydration

Journal of Molecular Catalysis ◽

10.1016/0304-5102(81)85044-4 ◽

1981 ◽

Vol 12 (3) ◽

pp. 389-391 ◽

Cited By ~ 7

Author(s):

T.T. Moxley ◽

B.C. Gates

Keyword(s):

Ion Exchange ◽

Exchange Resin ◽

Ion Exchange Resin ◽

Resin Catalyst

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Resin Material Used in Methyl Acrylate Hydrolysis Reaction

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.1035.307 ◽

2014 ◽

Vol 1035 ◽

pp. 307-312 ◽

Cited By ~ 1

Author(s):

Ya Ping Li ◽

Quan Huo ◽

Cun Cun Zuo ◽

Sha Sha Cao ◽

Er Qiang Wang

Keyword(s):

Experimental Data ◽

Methyl Acrylate ◽

Exchange Resin ◽

Cation Exchange Resin ◽

Reaction System ◽

Ion Exchange Resin ◽

High Energy ◽

Molar Ratio ◽

Resin Catalyst ◽

Hydrolysis Of

In this work, the ion exchange resin catalyst named D072 were used in the hydrolysis of a methyl acrylate to acrylic acid and methanol firstlyand chemical equilibrium would be achieved during the process of the reversible reaction system. The influences of parameters such as dosage of catalyst, initial reactants molar ratio and reaction temperature were investigated. Meanwhile, the reusability of cation-exchange resin was studied, and no phenomenon of deactivation was found with using of reused catalyst. Moreover, the experimental data were analyzed by the pseudo-homogeneous (PH) model and the hydrolysis dynamics equation of methyl acrylate was obtained and found that the activation energy of the reaction was 118.37 KJ/mol in the presence of D072. Based on the result, high energy would be needed to the hydrolysis of methyl acrylate in using D072 resin as catalyst.

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Synthesis of Epihalohydrins by Dehydrohalogenation of Glycerol Dihalohydrins - Utilization of a Basic Ion-Exchange Resin

Australian Journal of Chemistry ◽

10.1071/ch9921327 ◽

1992 ◽

Vol 45 (8) ◽

pp. 1327

Author(s):

M Dargelos ◽

ME Borredon ◽

A Gaset

Keyword(s):

Reaction Time ◽

Ion Exchange ◽

Room Temperature ◽

Exchange Resin ◽

Ion Exchange Resin ◽

Organic Medium ◽

Short Reaction Time ◽

Hydrolysis Of

Dehydrohalogenation of a mixture of glycerol 1,3- and 2,3-dihalohydrins by a strong basic ion-exchange resin (IRA 440 and A 26) at room temperature in an organic medium quantitatively leads to the corresponding epihalohydrin (1a; X = Cl), and (1b; X = Br) in a very short reaction time. Hydrolysis of the epihalohydrin does not occur under these conditions.

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