Construction of chitosan-based fluorescent probe for real-time monitoring of viscosity changes in living cells with low cytotoxicity and high photostability
Real-time monitoring of the cytochrome P450 1A1 (CYP1A1) activity in complex biological systems via a practical tool is highly sought after because of its significant role in the metabolism and bioactivation of various xenobiotics.
A new rhodol-hemicyanine based ratiometric and reversible fluorescent probe has been developed for real-time monitoring of glutathione dynamics in living cells.
Nitric oxide (NO) is an important cellular messenger molecule in the cardiovascular, nervous and immune systems. Real-time monitoring of NO activity in specific organelles of live cells is important to...
Through rational design, two new mitochondria-targeted fluorescent viscosity probes were developed, which exhibited favorable properties such as large turn on fluorescence signal, good selectivity, low cytotoxicity, and high colocation coefficient (>0.90).