A highly selective ratiometric fluorescent probe based on naphthalimide for detection and imaging of CYP1A1 in living cells and zebrafish

The Analyst ◽  
2019 ◽  
Vol 144 (24) ◽  
pp. 7390-7397 ◽  
Author(s):  
Hefang Ji ◽  
Xiuxuan Zhang ◽  
Yanpeng Dai ◽  
Tianzi Xue ◽  
Saima Misal ◽  
...  

Real-time monitoring of the cytochrome P450 1A1 (CYP1A1) activity in complex biological systems via a practical tool is highly sought after because of its significant role in the metabolism and bioactivation of various xenobiotics.

The Analyst ◽  
2019 ◽  
Vol 144 (24) ◽  
pp. 7457-7462 ◽  
Author(s):  
Minghao Ren ◽  
Linfang Wang ◽  
Xin Lv ◽  
Yuanqiang Sun ◽  
Hu Chen ◽  
...  

A new rhodol-hemicyanine based ratiometric and reversible fluorescent probe has been developed for real-time monitoring of glutathione dynamics in living cells.


Biomaterials ◽  
2015 ◽  
Vol 53 ◽  
pp. 669-678 ◽  
Author(s):  
Ming-Yu Wu ◽  
Kun Li ◽  
Yan-Hong Liu ◽  
Kang-Kang Yu ◽  
Yong-Mei Xie ◽  
...  

The Analyst ◽  
2019 ◽  
Vol 144 (16) ◽  
pp. 4972-4977 ◽  
Author(s):  
Wenjie Gao ◽  
Yanyan Ma ◽  
Weiying Lin

A mitochondria-targeted and red-emissive ratiometric fluorescent probe for fast imaging of SO2 in living cells and zebrafish has been developed, and the changes of SO2 in living mice have been visualized in real time with this probe.


RSC Advances ◽  
2019 ◽  
Vol 9 (39) ◽  
pp. 22348-22354 ◽  
Author(s):  
Junwei Shi ◽  
Wei Shu ◽  
Yong Tian ◽  
Yulong Wu ◽  
Jing Jing ◽  
...  

A real-time ratiometric fluorescent probe (IN-CZ) for highly selective detection of sulfite was designed and synthesized, which is based on modulating the intramolecular charge transfer of the hemicyanine dye platform.


The Analyst ◽  
2021 ◽  
Author(s):  
Liang Zhao ◽  
Zhenlong Huang ◽  
Daqing Ma ◽  
Yu Yan ◽  
Xinfu Zhang ◽  
...  

Nitric oxide (NO) is an important cellular messenger molecule in the cardiovascular, nervous and immune systems. Real-time monitoring of NO activity in specific organelles of live cells is important to...


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