ASR (Acceleration Slip Regulation) is the extension based on ABS. ABS and ASR are called by a joint name as slip regulation control system. Compared with two wheel drive car, four-wheel drive car has many defects, which is like snatch operation tedious and other defects. This paper has analyzed drive characteristic of four-wheel drive car and established drive simplify mathematical model. According to the mathematical model, we have established drive simulation model in MATLAB/SIMULINK environment, and made simulated analysis of different road surfaces for the model. The result indicated that slip regulation control system played preferable inhibiting effect for drive wheel spike of four-wheel drive car, and it can obtain a certain improvement of dynamic property. It verified feasibility of control algorithm and validity of control strategy at the same time.