Self-cleaning coatings are getting tremendous attention from both the academic interest and industrial communities. Among the two kinks of self-cleaning coatings, which are super-hydrophobic and super-hydrophilic coatings, the super-hydrophilic self-cleaning coating comprised of TiO2/doped-TiO2has four unique features when exposed to ultraviolet (UV) light or sunlight, which are self-cleaning property, anti-bacterial properties, environmental friendly, and visible-light photocatalysts and indoor usage. And PU-TiO2self-cleaning coating produced by “grafting” method, which can accomplish stable chemical attachment between the nTiO2and the PU substrates, may potentially show an increase of the thermal properties, an increase of the amount of active sites for photo-catalysis, and a decrease in the self-degradation of the resulting polymer nanocomposite than the traditional mechanical shear method. There is a tremendous scope for the application of polyurethane-nTiO2self-cleaning coatings in industrial, health care and consumer sectors.