Continuous CHO cell cultures with improved recombinant protein productivity by using mannose as carbon source: Metabolic analysis and scale-up simulation

2011 ◽  
Vol 66 (11) ◽  
pp. 2431-2439 ◽  
Author(s):  
Julio Berrios ◽  
Claudia Altamirano ◽  
Nelson Osses ◽  
Ramon Gonzalez
Keyword(s):  
Carbon Source ◽  
Recombinant Protein ◽  
Cell Cultures ◽  
Scale Up ◽  
Cho Cell ◽  
Metabolic Analysis ◽  
Recombinant Protein Productivity ◽  
Protein Productivity

Engineering CHO cell growth and recombinant protein productivity by overexpression of miR-7

2011 ◽  
Vol 151 (2) ◽  
pp. 204-211 ◽  
Author(s):  
N. Barron ◽  
N. Kumar ◽  
N. Sanchez ◽  
P. Doolan ◽  
C. Clarke ◽  
...  
Keyword(s):  
Cell Growth ◽  
Recombinant Protein ◽  
Cho Cell ◽  
Recombinant Protein Productivity ◽  
Protein Productivity

scholarly journals Enhanced Recombinant Protein Productivity by Genome Reduction in Bacillus subtilis

DNA Research ◽  
2008 ◽  
Vol 15 (2) ◽  
pp. 73-81 ◽  
Author(s):  
T. Morimoto ◽  
R. Kadoya ◽  
K. Endo ◽  
M. Tohata ◽  
K. Sawada ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Recombinant Protein ◽  
Genome Reduction ◽  
Recombinant Protein Productivity ◽  
Protein Productivity

Overexpression of the mitochondrial pyruvate carrier reduces lactate production and increases recombinant protein productivity in CHO cells

2020 ◽  
Vol 117 (9) ◽  
pp. 2633-2647
Author(s):  
Dubhe B. Bulté ◽  
Laura A. Palomares ◽  
Carolina Gómez Parra ◽  
Juan Andrés Martínez ◽  
Martha A. Contreras ◽  
...  
Keyword(s):  
Recombinant Protein ◽  
Cho Cells ◽  
Lactate Production ◽  
Recombinant Protein Productivity ◽  
Mitochondrial Pyruvate Carrier ◽  
Protein Productivity
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