Evaluation of the permeability and potential toxicity of polycyclic aromatic hydrocarbons to pulmonary surfactant membrane by the parallel artificial membrane permeability assay model

Chemosphere ◽  
2021 ◽  
pp. 132485
Author(s):  
Yan Cao ◽  
Linfeng Zhang ◽  
Yingxue Geng ◽  
Yingjie Li ◽  
Qun Zhao ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Membrane Permeability ◽  
Aromatic Hydrocarbons ◽  
Pulmonary Surfactant ◽  
Artificial Membrane ◽  
Potential Toxicity ◽  
Polycyclic Aromatic ◽  
Permeability Assay

Measurement, Source-Profiling and Potential Toxicity of Polycyclic Aromatic Hydrocarbons in an Agrarian Soil

2020 ◽  
Vol 7 (3) ◽  
pp. 827-844
Author(s):  
Adebanjo J. Anifowose ◽  
Ayomide O. Ogundola ◽  
Bolanle M. Babalola ◽  
Shola H. Awojide
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Potential Toxicity ◽  
Polycyclic Aromatic

Contribution of commonly analyzed polycyclic aromatic hydrocarbons (PAHs) to potential toxicity in early life stages of rainbow trout (Oncorhynchus mykiss)

2006 ◽  
Vol 63 (6) ◽  
pp. 1320-1333 ◽  
Author(s):  
Henrik Sundberg ◽  
Rasha Ishaq ◽  
Ulla Tjärnlund ◽  
Gun Åkerman ◽  
Kerstin Grunder ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Rainbow Trout ◽  
Oncorhynchus Mykiss ◽  
Aromatic Hydrocarbons ◽  
Environmental Protection Agency ◽  
Potential Toxicity ◽  
Total Extract ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Erod Induction ◽  
Polycyclic Aromatic

In a series of bio-effect-directed fractionation experiments, we investigated the potential toxicity of sediment extracts from a contaminated bay. A previous study investigated abnormalities and hepatic ethoxyresorufin O-deethylase (EROD) activities in rainbow trout (Oncorhynchus mykiss) larvae by exposing newly fertilized eggs to the total extract and to fractions separated by degree of aromaticity. A major part of the potential toxicity was isolated in a fraction containing polycyclic aromatic compounds (PACs). In this study, we prepared a synthetic PAC mixture with 17 commonly analyzed polycyclic aromatic hydrocarbons (PAHs) in amounts equimolar to those found in the sediment PAC fraction. The 17 PAHs, which included 11 of the 16 United States Environmental Protection Agency (US EPA) priority PAHs, were unable to account for the toxicopathic effects observed and could explain less than 4% of the total EROD induction. The lack of a clear relationship between toxicopathic effects and EROD induction underlines the need for a battery of biomarkers for estimating environmental risk. These results reveal the limits of our knowledge regarding compounds responsible for potential toxicity in field situations.

The temporal distribution, source and potential toxicity of polycyclic aromatic hydrocarbons in a sediment core from an urban lake in Wuhan, China

2015 ◽  
Vol 17 (4) ◽  
pp. 825-834 ◽  
Author(s):  
Qian Lu ◽  
Zeyu Yang ◽  
Laiyan Wu ◽  
Xinchao Ruan ◽  
Wenwen Yang
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Sediment Core ◽  
Aromatic Hydrocarbons ◽  
Temporal Distribution ◽  
Urban Lake ◽  
Potential Toxicity ◽  
Polycyclic Aromatic

The temporal distribution, source and toxicity of PAHs and APAHs in a sediment core from an urban lake in Wuhan, were studied.

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