Biomechanical behavior of brain injury caused by sticks using finite element model and Hybrid-III testing

Using a continuum approach for modeling the constitutive mechanical behavior of the intervertebral disk’s annulus fibrosus holds the potential for facilitating the correlation of morphology and biomechanics of this clinically important tissue. Implementation of a continuum representation of the disk’s tissues into computational models would yield a particularly valuable tool for investigating the effects of degenerative disease. However, to date, relevant efforts in the literature towards this goal have been limited due to the lack of a computationally tractable and implementable constitutive function. In order to address this, annular specimens harvested from a total of 15 healthy and degenerated intervertebral disks were tested under planar biaxial tension. Predictions of a strain energy function, which was previously shown to be unconditionally convex, were fit to the experimental data, and the optimized coefficients were used to modify a previously validated finite element model of the L4/L5 functional spinal unit. Optimization of material coefficients based on experimental results indicated increases in the micro-level orientation dispersion of the collagen fibers and the mechanical nonlinearity of these fibers due to degeneration. On the other hand, the finite element model predicted a progressive increase in the stress generation in annulus fibrosus due to stepwise degeneration of initially the nucleus and then the entire disk. Range of motion was predicted to initially increase with the degeneration of the nucleus and then decrease with the degeneration of the annulus in all rotational loading directions, except for axial rotation. Overall, degeneration was observed to specifically impact the functional effectiveness of the collagen fiber network of the annulus, leading to changes in the biomechanical behavior at both the tissue level and the motion-segment level.

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Experimentally validated three-dimensional finite element model of the rat for mild traumatic brain injury

Medical & Biological Engineering & Computing ◽

10.1007/s11517-012-1004-7 ◽

2012 ◽

Vol 51 (3) ◽

pp. 353-365 ◽

Cited By ~ 24

Author(s):

Michael Lamy ◽

Daniel Baumgartner ◽

Narayan Yoganandan ◽

Brian D. Stemper ◽

Rémy Willinger

Keyword(s):

Traumatic Brain Injury ◽

Finite Element ◽

Brain Injury ◽

Finite Element Model ◽

Mild Traumatic Brain Injury ◽

Three Dimensional ◽

Element Model ◽

Dimensional Finite Element ◽

Three Dimensional Finite Element

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Effect of Aging on Brain Injury Prediction in Rotational Head Trauma—A Parameter Study with a Rat Finite Element Model

Traffic Injury Prevention ◽

10.1080/15389588.2015.1021416 ◽

2015 ◽

Vol 16 (sup1) ◽

pp. S91-S99 ◽

Cited By ~ 8

Author(s):

Jacobo Antona-Makoshi ◽

Erik Eliasson ◽

Johan Davidsson ◽

Susumu Ejima ◽

Koshiro Ono

Keyword(s):

Finite Element ◽

Brain Injury ◽

Finite Element Model ◽

Head Trauma ◽

Element Model ◽

Parameter Study ◽

Injury Prediction

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A Computational Biomechanics Human Body Model Coupling Finite Element and Multibody Segments for Assessment of Head/Brain Injuries in Car-To-Pedestrian Collisions

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17020492 ◽

2020 ◽

Vol 17 (2) ◽

pp. 492 ◽

Cited By ~ 4

Author(s):

Chao Yu ◽

Fang Wang ◽

Bingyu Wang ◽

Guibing Li ◽

Fan Li

Keyword(s):

Finite Element ◽

Brain Injury ◽

The Netherlands ◽

Finite Element Model ◽

Element Model ◽

The Body ◽

Human Model ◽

Computational Biomechanics ◽

Head Kinematics ◽

The Impact

It has been challenging to efficiently and accurately reproduce pedestrian head/brain injury, which is one of the most important causes of pedestrian deaths in road traffic accidents, due to the limitations of existing pedestrian computational models, and the complexity of accidents. In this paper, a new coupled pedestrian computational biomechanics model (CPCBM) for head safety study is established via coupling two existing commercial pedestrian models. The head–neck complex of the CPCBM is from the Total Human Model for Safety (THUMS, Toyota Central R&D Laboratories, Nagakute, Japan) (Version 4.01) finite element model and the rest of the parts of the body are from the Netherlands Organisation for Applied Scientific Research (TNO, The Hague, The Netherlands) (Version 7.5) multibody model. The CPCBM was validated in terms of head kinematics and injury by reproducing three cadaveric tests published in the literature, and a correlation and analysis (CORA) objective rating tool was applied to evaluate the correlation of the related signals between the predictions using the CPCBM and the test results. The results show that the CPCBM head center of gravity (COG) trajectories in the impact direction (YOZ plane) strongly agree with the experimental results (CORA ratings: Y = 0.99 ± 0.01; Z = 0.98 ± 0.01); the head COG velocity with respect to the test vehicle correlates well with the test data (CORA ratings: 0.85 ± 0.05); however, the correlation of the acceleration is less strong (CORA ratings: 0.77 ± 0.06). No significant differences in the behavior in predicting the head kinematics and injuries of the tested subjects were observed between the TNO model and CPCBM. Furthermore, the application of the CPCBM leads to substantial reduction of the computation time cost in reproducing the pedestrian head tissue level injuries, compared to the full-scale finite element model, which suggests that the CPCBM could present an efficient tool for pedestrian brain-injury research.

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Development of a Finite Element Model for Blast Brain Injury and the Effects of CSF Cavitation

Annals of Biomedical Engineering ◽

10.1007/s10439-012-0519-2 ◽

2012 ◽

Vol 40 (7) ◽

pp. 1530-1544 ◽

Cited By ~ 103

Author(s):

Matthew B. Panzer ◽

Barry S. Myers ◽

Bruce P. Capehart ◽

Cameron R. Bass

Keyword(s):

Finite Element ◽

Brain Injury ◽

Finite Element Model ◽

Element Model

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Finite Element Model Study of Head Impact Based on Hybrid III Head Acceleration: The Effects of Rotational and Translational Acceleration

Journal of Biomechanical Engineering ◽

10.1115/1.2794187 ◽

1995 ◽

Vol 117 (3) ◽

pp. 319-328 ◽

Cited By ~ 31

Author(s):

Kazunari Ueno ◽

John W. Melvin

Keyword(s):

Finite Element ◽

Finite Element Model ◽

Maximum Shear Stress ◽

Element Model ◽

Head Acceleration ◽

Model Study ◽

Rotational Components ◽

Hybrid Iii ◽

Dimensional Finite Element ◽

Translational Acceleration

The translational and rotational components of acceleration measured at the center of gravity of a Hybrid III dummy head were used to investigate their individual and combined effects on a two-dimensional finite element model of the human brain. Each component of acceleration generated distinct patterns of deformation. Although translational acceleration is related to pressure and rotational acceleration has a dominant effect on shear deformations, complete acceleration (combination of translation and rotation) yielded the highest values in all stresses and produced a maximum shear stress at the top of the brain.

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