The stress relationship between the artifical knee-joints of the same pairing and crossed pairing was studied by the contrastive contact analysis of finite element simulation in different angles and conditions. The service lives of the artifical knee-joints of different pairing were studied based on the above result and Archard wear design calculation theory to expand the application of existing artificial knee-joints. The result shows that, the maximal contact stresses of the artifical knee-joints of crossed pairing are more than those of the artifical knee-joints of the same pairing, and the more different pairing types are, the more obvious stress growths are. The service life of the artifical knee-joint of 3/3 pairing is 28.42 years, and the service lives of 3/2.5 pairing and 3/4 pairing are 27.08 years and 25.76 years respectively.