Reproducibility in nerve conduction studies and F-wave analysis

2008 ◽  
Vol 119 (9) ◽  
pp. 2070-2073 ◽  
Author(s):  
Denise Spinola Pinheiro ◽  
Gilberto Mastrocola Manzano ◽  
João Antonio Maciel Nóbrega
2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Safa Yousif ◽  
Ammar Ahmed ◽  
Ahmed Abdelhai ◽  
Afraa Musa

Background. Nerve conduction studies (NCS) are electrodiagnostic tests used to evaluate peripheral nerves functions and aid in the assessment of patients with neuromuscular complaints. There is contrasting evidence concerning the use of NCS in the assessment of patients with lumbosacral radiculopathy. Objectives. This study was conducted to evaluate nerve conduction studies abnormalities in patients with lumbosacral radiculopathy and to find out their relation to abnormal physical examination findings. Materials and Methods. Twenty-seven patients with lumbosacral radiculopathy caused by L4/5 or L5/S1 intervertebral disc prolapse confirmed by magnetic resonance imaging (MRI) were recruited in the study. Twenty-five healthy subjects matched in age and sex served as control. Motor nerve conduction study bilaterally for both common peroneal and tibial nerves, F-wave for both nerves, and H-reflex had been conducted. Results. No significant difference was found in the motor nerve conduction study parameters (latency, amplitude, and conduction velocity) between the patients group and the control group. There was significant prolongation in H-reflex latency of both symptomatic and asymptomatic side in the patients group compared to the control group ( P < 0.05 ). Also, F-wave latencies (F minimum, F maximum, and F mean) of the tibial nerve were significantly prolonged ( P < 0.05 ) compared to control. Conclusion. Prolonged H-reflex latency was the commonest encountered abnormality in our study followed by F-wave latencies of the tibial nerve.


1995 ◽  
Vol 95 (3) ◽  
pp. P48
Author(s):  
A. Polo ◽  
A. Zambito ◽  
P. Manganotti ◽  
R. Aldegheri ◽  
G. Trivella ◽  
...  

2000 ◽  
Vol 5 (3) ◽  
pp. 5-6
Author(s):  
Charles N. Brooks

Abstract Previous issues of The Guides Newsletter have presented overviews of electrodiagnostic evaluation, including electromyography, nerve conduction studies, and somatosensory-evoked responses. This article contains suggestions for nonelectromyographers who read reports and identify questionable uses of electrodiagnosis, specifically for the evaluation of radiculopathy and focal neuropathy (eg, nerve entrapments), the two most common presentations. Some subtle abnormalities (eg, changes in motor unit recruitment pattern, changes in firing rate, or reduction in motor units recruited) often are overinterpreted by poorly trained or inexperienced electromyographers. Nerve conduction studies often are overused and may accompany the electromyogram without apparent indication, but they are nearly useless in diagnosing radiculopathy and should be included only for nerve entrapment or differential diagnosis of plexus injury. Nerve conduction studies often are accompanied by F waves and H reflexes. The F wave helps assess proximal portions of nerves and is used primarily in the diagnosis of Landry-Guillain-Barré syndrome but has poor sensitivity and specificity in evaluation of radiculopathy or entrapment neuropathy. The H reflex is used primarily in S1 radiculopathy evaluation. The article includes six questions a clinician should bear in mind while interpreting the electrodiagnostic report. Improperly trained physicians may report false positive or negative results, so examiners should be aware of the qualifications of physicians to whom they refer their patients.


2018 ◽  
Vol 89 (11) ◽  
pp. 1145-1151 ◽  
Author(s):  
Kathrin Doppler ◽  
Helena Stengel ◽  
Luise Appeltshauser ◽  
Julian Grosskreutz ◽  
Judy King Man Ng ◽  
...  

ObjectivesRecently, IgG autoantibodies against different paranodal proteins have been detected and this has led to important advances in the management of inflammatory neuropathies. In contrast, not much is known on IgM autoantibodies against paranodal proteins.MethodsIn the present study, we screened a large cohort of patients (n=140) with inflammatory neuropathies for IgM autoantibodies against neurofascin-155, neurofascin-186 or contactin-1.ResultsIgM autoantibodies against neurofascin-155 were detected by ELISA in five patients, four with inflammatory demyelinating polyradiculoneuropathy (CIDP) and one with Guillain-Barré syndrome (GBS), and were confirmed by ELISA-based preabsorption experiments and Western blot. Titres ranged from 1:100 to 1:400. We did not detect IgM anti-neurofascin-186 or anti-contactin-1 antibodies in this cohort. All patients presented with distally accentuated tetraparesis and hypesthesia. Remarkably, tremor was present in three of the patients with CIDP and occurred in the patients with GBS after the acute phase of disease. Nerve conduction studies revealed prolonged distal motor latencies and F wave latencies. Nerve biopsies showed signs of secondary axonal damage in three of the patients, demyelinating features in one patient. Teased fibre preparations did not demonstrate paranodal damage.ConclusionIn summary, IgM neurofascin-155 autoantibodies may be worth testing in patients with inflammatory neuropathies. Their pathogenic role needs to be determined in future experiments.


Author(s):  
Zahra Gorji ◽  
Hamid Azadeh

Background: Diagnosis of polyneuropathy is typically made using sensory and motor nerve conduction studies (NCS). These tests include measurement of amplitude, velocity, and delay of sensory and motor waves. These waves cannot assess the entire length of the nerve, proximal parts in special. F-wave is the only test capable of measuring the entire length of the nerve. The purpose of this study was to evaluate the value of F-wave in patients with diabetic polyneuropathy. Methods: This is a retrospective study assessing the value of nerve conduction studies and F-wave in the diagnosis of 148 patients with diabetic polyneuropathy referred to hospitals under the supervision of the University of Iowa from October 1, 2016, to September 5, 2018. Motor neurons of median, ulnar, peroneal, and tibial nerves and sensory neurons of median, ulnar, and sural nerves were assessed using two techniques of NCS and F-wave. Then the data were compared. Results: The results of this study showed that F-wave in all of the evaluated nerves (median, ulnar, tibial and peroneal) detected abnormalities to more extents than routine NCS (P <0.001). When total neuronal abnormalities were accumulated, this value was 82٪ for NCS, while 99٪ for the F wave (P < 0.001). Conclusion: Findings of the current study showed that the assessment of delayed nerve conducting through F-waves can diagnose diabetic polyneuropathy to better extents as compared to NCS. Further evaluations are recommended.


2019 ◽  
Vol 10 (02) ◽  
pp. 178-184
Author(s):  
Zaitoon Shivji ◽  
Anita Jabeen ◽  
Safia Awan ◽  
Sara Khan

ABSTRACT Introduction: Most neurophysiology departments around the world establish their own normative data. However, ethnic differences are not taken into account. Our aim was to establish normal nerve conduction studies (NCS) data for routinely tested nerves in individuals of Pakistani (South Asian) origin and to compare with Western published data. Materials and Methods: One hundred healthy adults’ nerves were assessed, using standardized techniques. Individuals were grouped into age groups. Gender differences were assessed. Results: Of the 100 volunteers, 49 were female and 51 were male. Their mean age was 39.8 years. Findings showed statistically significant prolongation of median distal motor latency (DML) and F-wave latency with age and reduction of median, ulnar, and sural sensory amplitudes as age increased. Gender differences showed consistent difference in the normal values for median, ulnar, and peroneal DMLs and respective F-wave latencies, which were significantly shorter in females. Sensory amplitudes of tested upper extremity nerves were significantly lower in males. Comparing with available data, our findings are similar to the Saudi population but significantly different from the American and multiethnic Malaysian populations. Pakistani individuals generally have significantly higher amplitudes and faster conduction velocities with similarities to South Asian studies. Conclusions: We recommend normative NCS parameters for commonly tested nerves for the Pakistani population, using standardized techniques to ensure highest quality testing and outcomes.


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