Detection of proximal conduction blocks using a triple stimulation technique improves the early diagnosis of Guillain–Barré syndrome

2018 ◽  
Vol 129 (1) ◽  
pp. 127-132 ◽  
Author(s):  
Amandine Sevy ◽  
Aude-Marie Grapperon ◽  
Emmanuelle Salort Campana ◽  
Emilien Delmont ◽  
Shahram Attarian
Keyword(s):  
Early Diagnosis ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Stimulation Technique ◽  
Triple Stimulation Technique

scholarly journals Rare variant of Guillain-Barré syndrome after chikungunya viral fever

2019 ◽  
Vol 12 (4) ◽  
pp. e228845 ◽  
Author(s):  
Sajid Hameed ◽  
Sara Khan
Keyword(s):  
Emergency Department ◽  
Early Diagnosis ◽  
Symptom Onset ◽  
Complete Resolution ◽  
Neurological Complications ◽  
Acute Onset ◽  
Guillain Barre Syndrome ◽  
Ventilator Support ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Chikungunya (CHIK) viral fever is a self-limiting illness that presents with severe debilitating arthralgia, myalgia, fever and rash. Neurological complications are rare. We present a case of a 36-year-old woman who presented with acute onset progressive difficulty swallowing and left arm weakness. She was diagnosed with CHIK viral fever 4 weeks prior to admission. After investigations, she was diagnosed with a pharyngeal–cervical–brachial variant of Guillain-Barré syndrome. In hospital, she required ventilator support. Her condition improved after five sessions of intravenous immunoglobulin with almost complete resolution within 6 months of symptom onset. With frequent CHIK outbreaks, the neurological complications are increasingly seen in the emergency department. The knowledge of these associations will result in early diagnosis and treatment.

scholarly journals Guillain-Barre syndrome and the clinical importance of a early diagnosis for a better prognosis

2015 ◽  
Vol 357 ◽  
pp. e452-e453
Author(s):  
R.V.B. Caldeira ◽  
Y.C. Machado ◽  
M.C. Mota ◽  
T.B. Machado ◽  
N.C.M. Queiroz ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Clinical Importance ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals An Atypical Case of Mild COVID-19 Infection with Severe Guillain-Barré Syndrome as Neurological Manifestation

2021 ◽  
Author(s):  
Debasis Behera ◽  
Ruchi Rekha Behera ◽  
Suman Kumar Jagaty ◽  
Rekha Das ◽  
Rajesh Venkataram ◽  
...  
Keyword(s):  
Critical Illness ◽  
Early Diagnosis ◽  
Nerve Fibers ◽  
Guillain Barre Syndrome ◽  
Atypical Case ◽  
Direct Damage ◽  
Guillain Barré Syndrome ◽  
Neurotoxic Effects ◽  
Specific Receptors ◽  
Guillain Barré

Abstract Introduction More than 80 million people have been infected with coronavirus disease 2019 (COVID-19) infection worldwide till date with more than 17,00000 fatalities. Although COVID-19 commonly affects respiratory system in the form of cough and dyspnea, a neurotropic presentation has been described in one-third of patients. Objective We report an atypical case of COVID-19 with mild symptoms who presented to our hospital with features suggestive of severe Guillain-Barré syndrome (GBS). Discussion The mechanisms by which severe acute respiratory syndrome coronavirus 2 causes neurologic damage are multifactorial, including direct damage to specific receptors, cytokine-mediated injury, secondary hypoxia, and retrograde travel along nerve fibers. The pathogenesis of GBS secondary to COVID-19 is not yet well understood. It is hypothesized that viral illnesses-related GBS could be mediated due to autoantibodies or direct neurotoxic effects of viruses. Conclusion In this ongoing era of pandemic, it is very important for the clinicians to be aware of association of GBS with COVID-19, as early diagnosis and treatment of this complication could have gratifying results. It is also very important to differentiate GBS from critical illness neuropathy and respiratory distress secondary to COVID-19 itself, as treatment to the above conditions is quite different and inability to correctly diagnose could lead to significant increase in morbidity and mortality.

COVID-19 and Neurology – An Emerging Association

2021 ◽  
Vol 21 ◽  
Author(s):  
Amit Gupta ◽  
Prakrati Yadav ◽  
Deepak Kumar
Keyword(s):  
Early Diagnosis ◽  
Literature Search ◽  
Demyelinating Disease ◽  
Transverse Myelitis ◽  
Guillain Barre Syndrome ◽  
Neurological Manifestations ◽  
Guillain Barré Syndrome ◽  
Neurological Features ◽  
Guillain Barré ◽  
Google Search

Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus, which is a cause of the ongoing pandemic, has the potential to infect the nervous system and causing neurological manifestations. However, patients with primarily neurological symptoms are often overlooked and tested later. Objective : We aim to summarise all the neurological manifestations which are reported so far to aid in early diagnosis and preventingze all the neurological manifestations that are reported so far to aid in early diagnosis and prevent further complication of the disease. Methods and Material: We did a literature search on the topic using Google search engine through Google Scholar, PubMed, and WHO resources by keywords including Coronavirus, SARS-CoV-2, COVID-19, Clinical features, Stroke, Transverse myelitis, Encephalitis, Encephalopathy, Guillain-Barre syndrome, Hypogeusia, Hyposmia, Anosmia, and Neurological manifestations. Discussion: SARS-CoV-2 can affect the neuronal cells by both direct and indirect mechanisms. This can lead to various neurological manifestations ranging from subtle symptoms of myalgia, headache, dizziness, hypogeusia, hyposmia to dreaded complications like stroke, encephalitis, demyelinating disease like Guillain-Barre syndrome. Conclusions: Presentation of COVID-19 with neurological features is not uncommon, and these patients should be tested earlier to help in the prevention of transmission, early diagnosis, and management.

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