scholarly journals Neuroinfectious Diseases: Guillain Barre Syndrome Clinical Features Suggestive of Early Diagnosis

2017 ◽  
Vol 1 (1) ◽  
pp. 01-03
Author(s):  
Carlos Rath
Keyword(s):  
Early Diagnosis ◽  
Clinical Features ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Guillain-Barré syndrome triggered by surgery in a Chinese population: a multicenter retrospective study

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qiaoyu Gong ◽  
Shuping Liu ◽  
Yin Liu ◽  
Jiajia Yao ◽  
Xiujuan Fu ◽  
...  
Keyword(s):  
Clinical Features ◽  
Orthopedic Surgery ◽  
Southern China ◽  
Axonal Neuropathy ◽  
Trigger Factor ◽  
Guillain Barre Syndrome ◽  
Initial Symptoms ◽  
Guillain Barré Syndrome ◽  
Potential Trigger ◽  
Guillain Barré

Abstract Background Surgery is a potential trigger of Guillain-Barré syndrome (GBS), a disorder which leads to an autoimmune-mediated attack of peripheral nerves. The present study was designed to explore clinical features of post-surgical GBS compared with those of general GBS in order to provide better clinical advice to patients undergoing surgery. Methods The medical records of GBS patients who were seen at 31 tertiary hospitals in southern China between January 1, 2013 and September 30, 2016 were retrospectively analyzed. Post-surgical GBS was defined as symptoms of GBS within 6 weeks after surgery. Clinical features of post-surgical GBS are described and are compared with general GBS. Results Among the 1001 GBS patient cases examined in this study, 45 (4.5%) patient cases exhibited symptoms of GBS within 6 weeks of undergoing surgery. Within this group, 36 (80.0%) patients developed initial symptoms of limb weakness. The average interval between surgery and symptom onset was 13.31 days. The most common type of surgery which triggered GBS was orthopedic surgery, followed by neurological surgery. Compared to general GBS, post-surgical GBS was characterized by a higher proportion of severe patients (Hughes functional grading scale (HFGS) score ≥ 3) upon admission and at nadir, higher HFGS scores at discharge, and longer hospital stays. Post-surgical GBS patients also had a significantly higher frequency of the acute motor axonal neuropathy subtype (37.9 vs. 14.2, respectively; P = 0.001). Conclusion Surgery is probably a potential trigger factor for GBS, especially orthopedic surgery. Infections secondary to surgery may play a role. The possibility of preceding (post-operative) infections was not excluded in this study. Clinical presentation of post-surgical GBS is characterized by a more severe course and poorer prognosis, and should be closely monitored. Trial registration chicTR-RRc-17,014,152.

scholarly journals Clinical features and prognosis with Guillain-Barré syndrome

2011 ◽  
Vol 14 (2) ◽  
pp. 98 ◽  
Author(s):  
Sinan Akbayram ◽  
Cihangir Akgün ◽  
Refah Sayin ◽  
Mehmet-Selçuk Bektas ◽  
Murat Dogan ◽  
...  
Keyword(s):  
Clinical Features ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Rare variant of Guillain-Barré syndrome after chikungunya viral fever

2019 ◽  
Vol 12 (4) ◽  
pp. e228845 ◽  
Author(s):  
Sajid Hameed ◽  
Sara Khan
Keyword(s):  
Emergency Department ◽  
Early Diagnosis ◽  
Symptom Onset ◽  
Complete Resolution ◽  
Neurological Complications ◽  
Acute Onset ◽  
Guillain Barre Syndrome ◽  
Ventilator Support ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Chikungunya (CHIK) viral fever is a self-limiting illness that presents with severe debilitating arthralgia, myalgia, fever and rash. Neurological complications are rare. We present a case of a 36-year-old woman who presented with acute onset progressive difficulty swallowing and left arm weakness. She was diagnosed with CHIK viral fever 4 weeks prior to admission. After investigations, she was diagnosed with a pharyngeal–cervical–brachial variant of Guillain-Barré syndrome. In hospital, she required ventilator support. Her condition improved after five sessions of intravenous immunoglobulin with almost complete resolution within 6 months of symptom onset. With frequent CHIK outbreaks, the neurological complications are increasingly seen in the emergency department. The knowledge of these associations will result in early diagnosis and treatment.

scholarly journals Guillain-Barre syndrome- Rationale for physiotherapy management of the acute severe patient

1996 ◽  
Vol 52 (4) ◽  
pp. 85-87 ◽  
Author(s):  
Lynn Fearnhead ◽  
Vivian U. Fritz
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Supportive Care ◽  
Clinical Features ◽  
Guillain Barre Syndrome ◽  
Critical Importance ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Severe Patient

The critical importance of supportive care including physiotherapy to the acute severe Guillain-Barre patient is emphasised in numerous reports in the literature. However, there are no systematic studies of physiotherapy in Guillain-Barre syndrome (GBS). This article examines the aetiology, pathology, clinical features, prognosis and treatment of GBS with reference to the physiotherapists’ management of the acute severe patient treated in an intensive care unit.

HyperCKemia in Guillain-Barré Syndrome

2020 ◽  
Vol 83 (4) ◽  
pp. 415-420
Author(s):  
Seok-Jin Choi ◽  
Yoon-Ho Hong ◽  
Jun-Soon Kim ◽  
Je-Young Shin ◽  
Jung-Joon Sung
Keyword(s):  
Creatine Kinase ◽  
South Korea ◽  
Clinical Features ◽  
Serum Creatine Kinase ◽  
Guillain Barre Syndrome ◽  
Teaching Hospitals ◽  
Fisher Syndrome ◽  
Guillain Barré Syndrome ◽  
Male Sex ◽  
Guillain Barré

The aim of the present study was to investigate the frequency and clinical features of Guillain-Barré syndrome (GBS) with hyperCKemia. We retrospectively identified 139 patients with GBS at 2 teaching hospitals in South Korea. We excluded patients with Miller-Fisher syndrome (n = 19), acute bulbar palsy (n = 3), and those whose serum creatine kinase (CK) levels were not measured (n = 45). Twelve of 72 patients (16.7%) had transient hyperCKemia, defined as serum CK ≥300 IU/L. The frequency of male sex and non-demyelinating electrodiagnostic features were higher in patients with hyperCKemia than those without. Transient hyperCKemia, occasionally seen in patients with GBS may be associated with the non-demyelinating subtype.

Sign in / Sign up

Export Citation Format

Share Document