Effect of nutritional support on clinical outcome in patients at nutritional risk

2004 ◽  
Vol 23 (4) ◽  
pp. 539-550 ◽  
Author(s):  
Niels Johansen ◽  
Jens Kondrup ◽  
Lise Munk Plum ◽  
Line Bak ◽  
Pernille Nørregaard ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Rui Wang ◽  
Hongfei Cai ◽  
Yang Li ◽  
Caiwen Chen ◽  
Youbin Cui

Objective. Preoperative nutritional status of patients is closely associated with their recovery after the surgery. This study aims to ascertain the impact exerted by the nutritional risk screening on clinical outcome of patients with esophageal cancer. Methods. 160 patients with esophageal cancer aged over 60, having got therapy at the First Hospital of Jilin University from Jun 2016 to Feb 2017 were evaluated by adopting the NRS2002. 80 cases of patients got active therapy of nutritional support, and the other patients not supported nutritionally were selected as the control group. The comparison was drawn between two groups in serum albumin, serum immunoglobulin, postoperative complications, hospitalization, and hospitalization expenses. Results. For all the patients, in 3 and 7 days after the surgery, the serum albumin in the nutritionally supported group outstripped that in group without nutritional support (P<0.05) regardless of the nutritional risk. For the patients in the risk of nutrition, the IgA in the nutritionally supported group outstripped that of group without nutritional support (P<0.05) in 3 and 7 days before the surgery, and the serum IgG outstripped that of the group without nutritional support in 1 and 3 days before the surgery (P<0.05). In terms of the patients in the risk of nutrition, the average hospitalization of nutritionally supported group was shorter (P<0.05), and the average hospitalization expenses were lower compared with those of the group without nutritional support. And for the patients in no risk, the hospitalization expenses of supported group surmounted those of group without nutritional support (P<0.05), whereas the average hospitalization took on no statistic difference (P>0.05). Conclusion. For the patients in the risk of nutrition, preoperative nutritional support can facilitate the nutritional status and immunization-relative result after surgery, which shall also decrease the average hospitalization and hospitalization cost.


Nutrition ◽  
2012 ◽  
Vol 28 (10) ◽  
pp. 1022-1027 ◽  
Author(s):  
Bin Jie ◽  
Zhu-Ming Jiang ◽  
Marie T. Nolan ◽  
Shai-Nan Zhu ◽  
Kang Yu ◽  
...  

2003 ◽  
Vol 22 ◽  
pp. S85-S86 ◽  
Author(s):  
N. Johansen ◽  
J. Kondrup ◽  
L.M. Plum ◽  
L. Bak ◽  
P. Nørregaard ◽  
...  

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 42-43
Author(s):  
Rui Wang ◽  
Hongfei Cai ◽  
Youbin Cui

Abstract Background Preoperative nutritional status of patients is closely associated with their recovery after the surgery. This study aims to ascertain the impact exerted by the nutritional risk screening on clinical outcome of patients with esophageal cancer, to provide scientific determination of nutritional support for patients suffering from esophageal cancer. Methods 160 patients with esophageal cancer aged over 60, having got therapy at the First Hospital affiliated by Jilin University from Jun. 2016to Feb. 2017 were evaluated adopting the NRS2002. 80 cases of patients got active therapy of nutritional support, and the other patients not supported nutritionally were selected as the control group. The comparison was drawn between two groups in serum albumin, serum immunoglobulin, postoperative complications, hospitalization and hospitalization expenses. Experimental data were acquired through adopting t-test and χ2 test for statistical analysis. Results For all the patients, in 3 and7 days after the surgery, the serum albumin in the nutritionally supported group outstripped that in group without nutritional support (P < 0.05) regardless of the nutritional risk. For the patients in the risk of nutrition, the IgA in the nutritionally supported group outstripped that of group without nutritional support (P < 0.05) in 3 and 7 days before the surgery, and the serum IgG outstripped that of the group without nutritional support in 1 and 3 days before the surgery(P < 0.05). Two groups were not statistically different in the rate of postoperative complication (P > 0.05). In terms of the patients in the risk of nutrition, the average hospitalization of nutritionally supported group was shorter(P < 0.05), and the average hospitalization expenses were lower compared with those of the group without nutritional support. And for the patients in no risk, the hospitalization expenses of supported group surmounted those of group without nutritional support (P < 0.05), whereas the average hospitalization took on no statistic difference(P > 0.05). Conclusion For the patients in the risk of nutrition, preoperative nutritional support can facilitate the nutritional status and immunization-relative result after surgery, which shall also decrease the average hospitalization and hospitalization cost. Disclosure All authors have declared no conflicts of interest.


Nutrients ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 57
Author(s):  
Adam Brewczyński ◽  
Beata Jabłońska ◽  
Sławomir Mrowiec ◽  
Krzysztof Składowski ◽  
Tomasz Rutkowski

Malnutrition is a common problem in patients with head and neck cancer (HNC), including oropharyngeal cancer (OPC). It is caused by insufficient food intake due to dysphagia, odynophagia, and a lack of appetite caused by the tumor. It is also secondary to the oncological treatment of the basic disease, such as radiotherapy (RT) and chemoradiotherapy (CRT), as a consequence of mucositis with the dry mouth, loss of taste, and dysphagia. The severe dysphagia leads to a definitive total impossibility of eating through the mouth in 20–30% of patients. These patients usually require enteral nutritional support. Feeding tubes are a commonly used nutritional intervention during radiotherapy, most frequently percutaneous gastrostomy tube. Recently, a novel HPV-related type of OPC has been described. Patients with HPV-associated OPC are different from the HPV− ones. Typical HPV− OPC is associated with smoking and alcohol abuse. Patients with HPV+ OPC are younger and healthy (without comorbidities) at diagnosis compared to HPV− ones. Patients with OPC are at high nutritional risk, and therefore, they require nutritional support in order to improve the treatment results and quality of life. Some authors noted the high incidence of critical weight loss (CWL) in patients with HPV-related OPC. Other authors have observed the increased acute toxicities during oncological treatment in HPV+ OPC patients compared to HPV− ones. The aim of this paper is to review and discuss the indications for nutritional support and the kinds of nutrition, including immunonutrition (IN), in HNC, particularly OPC patients, undergoing RT/CRT, considering HPV status.


2019 ◽  
Vol 8 (7) ◽  
pp. 1065 ◽  
Author(s):  
Emilie Reber ◽  
Filomena Gomes ◽  
Maria F. Vasiloglou ◽  
Philipp Schuetz ◽  
Zeno Stanga

Malnutrition is an independent risk factor that negatively influences patients’ clinical outcomes, quality of life, body function, and autonomy. Early identification of patients at risk of malnutrition or who are malnourished is crucial in order to start a timely and adequate nutritional support. Nutritional risk screening, a simple and rapid first-line tool to detect patients at risk of malnutrition, should be performed systematically in patients at hospital admission. Patients with nutritional risk should subsequently undergo a more detailed nutritional assessment to identify and quantify specific nutritional problems. Such an assessment includes subjective and objective parameters such as medical history, current and past dietary intake (including energy and protein balance), physical examination and anthropometric measurements, functional and mental assessment, quality of life, medications, and laboratory values. Nutritional care plans should be developed in a multidisciplinary approach, and implemented to maintain and improve patients’ nutritional condition. Standardized nutritional management including systematic risk screening and assessment may also contribute to reduced healthcare costs. Adequate and timely implementation of nutritional support has been linked with favorable outcomes such as a decrease in length of hospital stay, reduced mortality, and reductions in the rate of severe complications, as well as improvements in quality of life and functional status. The aim of this review article is to provide a comprehensive overview of nutritional screening and assessment methods that can contribute to an effective and well-structured nutritional management (process cascade) of hospitalized patients.


2008 ◽  
Vol 27 (3) ◽  
pp. 340-349 ◽  
Author(s):  
Janice Sorensen ◽  
Jens Kondrup ◽  
Jacek Prokopowicz ◽  
Marc Schiesser ◽  
Lukas Krähenbühl ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document