Variation in Radiotherapy Target Volume Definition, Dose to Organs at Risk and Clinical Target Volumes using Anatomic (Computed Tomography) versus Combined Anatomic and Molecular Imaging (Positron Emission Tomography/Computed Tomography): Intensity-modulated Radiotherapy Delivered using a Tomotherapy Hi Art Machine: Final Results of the VortigERN Study

2012 ◽  
Vol 24 (10) ◽  
pp. e173-e179 ◽  
Author(s):  
S. Chatterjee ◽  
J. Frew ◽  
J. Mott ◽  
H. McCallum ◽  
P. Stevenson ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Organs At Risk ◽  
Intensity Modulated Radiotherapy ◽  
Target Volume ◽  
Emission Tomography ◽  
Intensity Modulated ◽  
Positron Emission ◽  
Target Volumes ◽  
Clinical Target Volumes

Volumetric and dosimetric comparison of computerised radiotherapy treatment plan between using positron emission tomography/computed tomography (PET/CT) and CT images for target delineation in non-small cell lung cancer patients

2016 ◽  
Vol 15 (2) ◽  
pp. 161-169
Author(s):  
Sanphat Sangudsup ◽  
Tawika Kaewchur ◽  
Waralee Teeyasoontranon ◽  
Pitchayaponne Klunklin ◽  
Nisa Chawapun ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Positron Emission Tomography ◽  
Organs At Risk ◽  
Small Cell ◽  
Emission Tomography ◽  
Target Coverage ◽  
Small Cell Lung ◽  
Positron Emission ◽  
Pet Ct

AbstractPurposeTo compare intensity-modulated radiation therapy (IMRT) treatment planning between using positron emission tomography/computed tomography (PET/CT) and CT for target volume delineation in patients with non-small cell lung cancer (NSCLC).MethodsNine NSCLC patients with PET/CT images were enrolled into this study. Gross tumour volumes (GTVs) were delineated by the PET visual assessment (PETvis), the automated PET (PETauto), standardised uptake value (SUV)>2·5 (PET2·5) and threshold 40% SUVmax (PET40), and CT-based method. For each patient, two IMRT treatment plans based on CT and PET/CT delineation were performed. The target coverage and the dose–volume parameters for organs at risk were analysed.ResultsThe PETauto referred to PET40 when SUVmax<7 and PET2·5 when SUVmax≥7. The mean GTVs were 15·04, 15·7 and 15·14 cc for PETauto, PETvis and CT based, respectively. The GTV of PETauto was not different from PETvis (p=0·441) and CT based (p=0·594). Based on CT delineation in IMRT planning, only 34% of the cases had sufficient PET/CT planning target volumes coverage, whereas the organs at risk dose parameters were not statistically significant (p>0·05).ConclusionsPET/CT enables more accurate assessment of tumour delineation for NSCLC, therefore improve target coverage in IMRT plan.

Sign in / Sign up

Export Citation Format

Share Document