A novel single-step explicit time-marching procedure with improved dissipative, dispersive and stability properties

2021 ◽  
Vol 386 ◽  
pp. 114077
Author(s):  
Delfim Soares
2018 ◽  
Vol 211 ◽  
pp. 17004
Author(s):  
Delfim Soares ◽  
Tales Vieira Sofiste ◽  
Webe João Mansur

In this work, a new time marching procedure is proposed for structural dynamics analyses. In this novel technique, time integration parameters are locally defined and different values may be attributed to each structural element of the model. In addition, the time integrators are evaluated according to the properties of the elements, and the user may select in which structural elements numerical dissipation will be introduced. Since the integration parameters are locally defined as function of the structural element itself, the time marching technique adapts according to the model, providing enhanced accuracy. The method is very simple to implement and it stands as an efficient, direct, single-step procedure. It is second order accurate, unconditionally stable, truly self-starting and it allows highly controllable algorithm dissipation in the higher modes. Numerical results are presented along the paper, illustrating the good performance of the new technique.


2005 ◽  
Vol 173 (4S) ◽  
pp. 240-240
Author(s):  
Premal J. Desai ◽  
David A. Hadley ◽  
Lincoln J. Maynes ◽  
D. Duane Baldwin

1996 ◽  
Vol 75 (03) ◽  
pp. 497-502 ◽  
Author(s):  
Hadewijch L M Pekelharing ◽  
Henne A Kleinveld ◽  
Pieter F C.C.M Duif ◽  
Bonno N Bouma ◽  
Herman J M van Rijn

SummaryLp(a) is an LDL-like lipoprotein plus an additional apolipoprotein apo(a). Based on the structural homology of apo(a) with plasminogen, it is hypothesized that Lp(a) interferes with fibrinolysis. Extracellular matrix (ECM) produced by human umbilical vein endothelial cells was used to study the effect of Lp(a) and LDL on plasminogen binding and activation. Both lipoproteins were isolated from the same plasma in a single step. Plasminogen bound to ECM via its lysine binding sites. Lp(a) as well as LDL were capable of competing with plasminogen binding. The degree of inhibition was dependent on the lipoprotein donor as well as the ECM donor. When Lp(a) and LDL obtained from one donor were compared, Lp(a) was always a much more potent competitor. The effect of both lipoproteins on plasminogen binding was reflected in their effect on plasminogen activation. It is speculated that Lp(a) interacts with ECM via its LDL-like lipoprotein moiety as well as via its apo(a) moiety.


1983 ◽  
Vol 49 (01) ◽  
pp. 024-027 ◽  
Author(s):  
David Vetterlein ◽  
Gary J Calton

SummaryThe preparation of a monoclonal antibody (MAB) against high molecular weight (HMW) urokinase light chain (20,000 Mr) is described. This MAB was immobilized and the resulting immunosorbent was used to isolate urokinase starting with an impure commercial preparation, fresh urine, spent tissue culture media, or E. coli broth without preliminary dialysis or concentration steps. Monospecific antibodies appear to provide a rapid single step method of purifying urokinase, in high yield, from a variety of biological fluids.


1962 ◽  
Vol 07 (02) ◽  
pp. 239-248 ◽  
Author(s):  
Walter H Seegers ◽  
Edmond R Cole ◽  
Ewa Marciniak

SummaryActivation of purified prothrombin with autoprothrombin C in the absence of calcium ions produces autoprothrombin I activity. The solubility, and stability properties of this autoprothrombin I are different from those of autoprothrombin I when obtained by activating prothrombin with calcium ions, platelet factor 3, and Ac-globulin.


ENTOMON ◽  
2018 ◽  
Vol 43 (4) ◽  
pp. 223-230
Author(s):  
S. Sunil Kumar ◽  
D.A. Evans ◽  
K. Muthulakshmi ◽  
T. DilipKumar ◽  
R. Heera Pillai ◽  
...  

Mosquito index study of three ecologically different ecozones of the Thiruvananthapuram district, Kerala showed sharp difference on the proportionate distribution of Aedes aegypti and Aedes albopictus. Human dengue viremia (HDV) was very high in those ecozones where A.aegypti density was high and HDV was low where A.albopictus was high. In a coastal zone of Thiruvananthapuram city, A. aegypti was the most abundant vector and in a hilly, arid suburban zone, A.albopictus was the abundant vector. In the urban zone both species of mosquitoes showed equal distribution. Study on the circulating serotypes in the serum of HDV by Single step single tube Multiplex PCR showed all the four serotypes viz DENV1, DENV2, DENV3 and DENV4 in patients of Thiruvananthapuram city, which indicated the possibility of Dengue Shock Syndrome, unless there is efficient vector management. Among the four dengue serotypes, Type 1 was the most abundant virus. Abundance of microhabitats in Thiruvananthapuram city, which support A. aegypti may be the reason for high prevalence of dengue fever in the urban zone.


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