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GLP-1/GIP/glucagon receptor triagonism gets its try in humans
Cell Metabolism
◽
10.1016/j.cmet.2021.12.010
◽
2022
◽
Vol 34
(1)
◽
pp. 3-4
Author(s):
Brian Finan
◽
Jonathan D. Douros
Keyword(s):
Glucagon Receptor
Download Full-text
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MIRIAM E. TUCKER
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Receptor Antagonists
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Novel glucagon receptor antagonist peptides improve glycaemic control and partially protect against streptozotocin induced diabetes in mice
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Antagonist Peptides
◽
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An Allosteric Glucagon Receptor Antagonist, LGD-6972, Displays Biased Receptor Signaling
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10.2337/db18-1117-p
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2018
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◽
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Author(s):
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◽
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Keyword(s):
Receptor Antagonist
◽
Receptor Signaling
◽
Glucagon Receptor
◽
Glucagon Receptor Antagonist
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Cholesterol 7 Alpha–Hydroxylase (CYP7A1) Activity and 7–Alpha–Hydroxy–4–Cholesten–3–One (C4) Are Not Translatable Biomarkers of Glucagon Receptor (GCGR) Activation
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10.2337/db18-1113-p
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◽
pp. 1113-P
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RAUL CAMACHO
◽
WENYU LI
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THOMAS KIRCHNER
◽
RUI ZHANG
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FANY BONILLA
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...
Keyword(s):
Glucagon Receptor
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MEDI0382, a GLP-1/Glucagon Receptor Dual Agonist, Shows Differential Brain Activation vs. Liraglutide in Mice
Diabetes
◽
10.2337/db18-1789-p
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2018
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LUKE K. BURKE
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ARTHUR R. LEWIS
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Evaluating the Sub-chronic Effects of MEDI0382, a GLP-1/Glucagon Receptor Dual Agonist, on Weight Loss in Male ob/ob Mice
Diabetes
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10.2337/db18-1890-p
◽
2018
◽
Vol 67
(Supplement 1)
◽
pp. 1890-P
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◽
CHRISTOPHER D. CHURCH
◽
SARAH WILL
◽
ANISH KONKAR
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JAMES TREVASKIS
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...
Keyword(s):
Weight Loss
◽
Glucagon Receptor
◽
Chronic Effects
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Diabetes
◽
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◽
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◽
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◽
pp. 1010-P
Author(s):
VICTORIA E. PARKER
◽
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◽
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◽
DAVID C. HORNIGOLD
◽
MAXIMILIAN G. POSCH
◽
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Amino Acids
◽
Fatty Acids
◽
Free Fatty Acids
◽
Receptor Activity
◽
Glucagon Receptor
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1870-P: Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression
Diabetes
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10.2337/db19-1870-p
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◽
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◽
pp. 1870-P
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SHELLY NASON
◽
TEAYOUN KIM
◽
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◽
BRIAN FINAN
◽
RICHARD DIMARCHI
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Hepatic Steatosis
◽
Leptin Receptor
◽
Receptor Expression
◽
Receptor Signaling
◽
Glucagon Receptor
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1813-P: Coadministration of a GLP-1/Glucagon Receptor Agonist with an FXR Agonist and ACC Inhibitor Reverses Nonalcoholic Steatohepatitis (NASH) in Diet-Induced and Biopsy-Confirmed Mice
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Receptor Agonist
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Glucagon Receptor
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1965-P: Glucagon Receptor Agonism Stimulates Body Weight Loss in Antibiotic Treatment in Obese Mice
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10.2337/db19-1965-p
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2019
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pp. 1965-P
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TEAYOUN KIM
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Obese Mice
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Glucagon Receptor
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